{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T01:59:39Z","timestamp":1760147979825,"version":"build-2065373602"},"reference-count":12,"publisher":"MDPI AG","issue":"6","license":[{"start":{"date-parts":[[2023,3,16]],"date-time":"2023-03-16T00:00:00Z","timestamp":1678924800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostics"],"abstract":"<jats:p>Necrotizing fasciitis is a relatively rare and serious fatal soft-tissue infection that is characterized by a rapidly spreading bacterial infection located in the subcutaneous tissues. We report a 59-year-old man who was diagnosed with acute necrotizing fasciitis, following a primary total knee replacement. He received primary total knee replacement that was uneventful and smooth intraoperatively. An immediate high fever was reported in the next few days, with several complications, confirming a diagnosis of necrotizing fasciitis. The most effective treatment for this disease is a rapid primary diagnosis and surgical debridement. Gold standard treatment includes intravenous therapy, such as antibiotics, surgical debridement, and intensive care. As a result of possible GI complications that triggered necrotizing fasciitis, the patient underwent flap reconstruction. This report\u2019s aim is to review the comprehensive treatment, management, and experience of necrotizing fasciitis, highlighting the roles with a multidisciplinary care team for improving the condition of this patient.<\/jats:p>","DOI":"10.3390\/diagnostics13061125","type":"journal-article","created":{"date-parts":[[2023,3,16]],"date-time":"2023-03-16T02:40:11Z","timestamp":1678934411000},"page":"1125","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["A Patient with Acute Necrotizing Fasciitis after a Total Knee Replacement: A Case Report"],"prefix":"10.3390","volume":"13","author":[{"given":"Shu-Hao","family":"Chang","sequence":"first","affiliation":[{"name":"Department of Orthopedics, Fu Jen Catholic University Hospital, Fu Jen Catholic University, No. 69, Guizi Rd., Taishan Dist., New Taipei City 24352, Taiwan"},{"name":"School of Medicine, College of Medicine, Fu Jen Catholic University, No. 510, Zhongzheng Rd., Xinzhuang Dist., New Taipei City 24205, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ching-Chuan","family":"Jiang","sequence":"additional","affiliation":[{"name":"Department of Orthopedics, Fu Jen Catholic University Hospital, Fu Jen Catholic University, No. 69, Guizi Rd., Taishan Dist., New Taipei City 24352, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tom J.","family":"Liu","sequence":"additional","affiliation":[{"name":"Division of Plastic Surgery, Department of Surgery, Fu Jen Catholic University Hospital, Fu Jen Catholic University, No. 69, Guizi Rd., Taishan Dist., New Taipei City 24352, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yu-Feng","family":"Kuo","sequence":"additional","affiliation":[{"name":"Department of Orthopedics, Fu Jen Catholic University Hospital, Fu Jen Catholic University, No. 69, Guizi Rd., Taishan Dist., New Taipei City 24352, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ping-Chun","family":"Yeh","sequence":"additional","affiliation":[{"name":"Department of Orthopedics, Fu Jen Catholic University Hospital, Fu Jen Catholic University, No. 69, Guizi Rd., Taishan Dist., New Taipei City 24352, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2023,3,16]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"2076","DOI":"10.1007\/s00167-011-1561-6","article-title":"Necrotizing fasciitis of the knee following primary total knee arthroplasty","volume":"19","author":"Steckel","year":"2011","journal-title":"Knee Surg. Sport. Traumatol. Arthrosc."},{"key":"ref_2","first-page":"380","article-title":"Total knee replacement subsequent to severe necrotising fasciitis of the lower limb","volume":"61","author":"Ling","year":"2006","journal-title":"Med. J. Malays."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1757-7241-17-28","article-title":"Necrotizing fasciitis of the lower extremity: A case report and current concept of diagnosis and management","volume":"17","author":"Naqvi","year":"2009","journal-title":"Scand. J. Trauma Resusc. Emerg. Med."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1136\/bmj.e4274","article-title":"Necrotising fasciitis","volume":"345","author":"Sultan","year":"2012","journal-title":"BMJ"},{"key":"ref_5","first-page":"238","article-title":"Necrotizing fasciitis. A rare complication of total hip replacement","volume":"15","author":"Tiwari","year":"2000","journal-title":"J. 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J."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1089\/wound.2021.0031","article-title":"Early Diagnosis and Surgical Management of Necrotizing Fasciitis of the Lower Extremities: Risk Factors for Mortality and Amputation","volume":"11","author":"Dekker","year":"2022","journal-title":"Adv. Wound Care"}],"container-title":["Diagnostics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2075-4418\/13\/6\/1125\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T18:56:21Z","timestamp":1760122581000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2075-4418\/13\/6\/1125"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,3,16]]},"references-count":12,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2023,3]]}},"alternative-id":["diagnostics13061125"],"URL":"https:\/\/doi.org\/10.3390\/diagnostics13061125","relation":{},"ISSN":["2075-4418"],"issn-type":[{"type":"electronic","value":"2075-4418"}],"subject":[],"published":{"date-parts":[[2023,3,16]]}}}