{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T04:38:49Z","timestamp":1787027929119,"version":"build-2736575974"},"reference-count":97,"publisher":"MDPI AG","issue":"9","license":[{"start":{"date-parts":[[2023,4,22]],"date-time":"2023-04-22T00:00:00Z","timestamp":1682121600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Ministry of Education of Spain","award":["FPU21\/04865"],"award-info":[{"award-number":["FPU21\/04865"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostics"],"abstract":"<jats:p>Background: Obesity and being overweight have become one of the world\u2019s most severe health issues, not only because of the pathology but also because of the development of related comorbidities. Even when children reach adulthood, the mother\u2019s environment during pregnancy has been found to have a significant impact on obesity prevention in children. Thus, both maternal dietary habits and other factors such as gestational diabetes mellitus, excessive weight gain during pregnancy, smoking, or endocrine factors, among others, could influence newborn growth, adiposity, and body composition at birth, in childhood and adolescence, hence programming health in adulthood. Methods: The aim of this review is to analyze the most recent human studies on the programming of fetal adipose tissue to determine which modifiable factors may influence adiposity and thus prevent specific disorders later in life by means of a bibliographic review of articles related to the subject over the last ten years. Conclusions: The importance of a healthy diet and lifestyle not only during pregnancy and the first months of life but also throughout childhood, especially during the first two years of life as this is a period of great plasticity, where the foundations for optimal health in later life will be laid, preventing the emergence of noncommunicable diseases including obesity, diabetes mellitus type 2, hypertension, being overweight, and any other pathology linked to metabolic syndrome, which is so prevalent today, through health programs beginning at a young age.<\/jats:p>","DOI":"10.3390\/diagnostics13091510","type":"journal-article","created":{"date-parts":[[2023,4,24]],"date-time":"2023-04-24T01:35:44Z","timestamp":1682300144000},"page":"1510","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Influence of Adipose Tissue on Early Metabolic Programming: Conditioning Factors and Early Screening"],"prefix":"10.3390","volume":"13","author":[{"given":"Maria","family":"Puche-Juarez","sequence":"first","affiliation":[{"name":"Department of Physiology, Faculty of Pharmacy, Campus Universitario de Cartuja, University of Granada, E-18071 Granada, Spain"},{"name":"Institute of Nutrition and Food Technology \u201cJos\u00e9 Mataix Verd\u00fa\u201d, University of Granada, E-18071 Granada, Spain"},{"name":"Nutrition and Food Sciences Ph.D. Program, University of Granada, E-18071 Granada, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan M.","family":"Toledano","sequence":"additional","affiliation":[{"name":"Department of Physiology, Faculty of Pharmacy, Campus Universitario de Cartuja, University of Granada, E-18071 Granada, Spain"},{"name":"Institute of Nutrition and Food Technology \u201cJos\u00e9 Mataix Verd\u00fa\u201d, University of Granada, E-18071 Granada, Spain"},{"name":"Nutrition and Food Sciences Ph.D. Program, University of Granada, E-18071 Granada, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8976-6296","authenticated-orcid":false,"given":"Julio J.","family":"Ochoa","sequence":"additional","affiliation":[{"name":"Department of Physiology, Faculty of Pharmacy, Campus Universitario de Cartuja, University of Granada, E-18071 Granada, Spain"},{"name":"Institute of Nutrition and Food Technology \u201cJos\u00e9 Mataix Verd\u00fa\u201d, University of Granada, E-18071 Granada, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3659-1757","authenticated-orcid":false,"given":"Javier","family":"Diaz-Castro","sequence":"additional","affiliation":[{"name":"Department of Physiology, Faculty of Pharmacy, Campus Universitario de Cartuja, University of Granada, E-18071 Granada, Spain"},{"name":"Institute of Nutrition and Food Technology \u201cJos\u00e9 Mataix Verd\u00fa\u201d, University of Granada, E-18071 Granada, Spain"},{"name":"Instituto de Investigaci\u00f3n Biosanitaria (IBS), E-18016 Granada, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9690-7851","authenticated-orcid":false,"given":"Jorge","family":"Moreno-Fernandez","sequence":"additional","affiliation":[{"name":"Department of Physiology, Faculty of Pharmacy, Campus Universitario de Cartuja, University of Granada, E-18071 Granada, Spain"},{"name":"Institute of Nutrition and Food Technology \u201cJos\u00e9 Mataix Verd\u00fa\u201d, University of Granada, E-18071 Granada, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,4,22]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"101082","DOI":"10.1016\/j.plipres.2020.101082","article-title":"Adipose tissue development and lipid metabolism in the human fetus: The 2020 perspective focusing on maternal diabetes and obesity","volume":"81","author":"Desoye","year":"2021","journal-title":"Prog. 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