{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T00:08:25Z","timestamp":1785802105636,"version":"3.56.0"},"reference-count":27,"publisher":"MDPI AG","issue":"9","license":[{"start":{"date-parts":[[2023,4,30]],"date-time":"2023-04-30T00:00:00Z","timestamp":1682812800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"FSBI \u201cEndocrinology Research Center\u201d of the Ministry of Health of Russia","award":["AAAA-B19-419121690050-8 123021000038-6"],"award-info":[{"award-number":["AAAA-B19-419121690050-8 123021000038-6"]}]},{"name":"FSBI \u201cEndocrinology Research Center\u201d of the Ministry of Health of Russia","award":["FWNR-2023-0006"],"award-info":[{"award-number":["FWNR-2023-0006"]}]},{"name":"RICEL\u2014Branch of IC&amp;G SB RAS","award":["AAAA-B19-419121690050-8 123021000038-6"],"award-info":[{"award-number":["AAAA-B19-419121690050-8 123021000038-6"]}]},{"name":"RICEL\u2014Branch of IC&amp;G SB RAS","award":["FWNR-2023-0006"],"award-info":[{"award-number":["FWNR-2023-0006"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostics"],"abstract":"<jats:p>Simultaneous pancreas\u2013kidney transplantation (SPKT) can improve long-term patient survival and restore endogenous insulin secretion in recipients with type 1 diabetes (T1D). There are currently few data on glucose fluctuations assessed by continuous glucose monitoring (CGM) after SPKT. Aim: to evaluate CGM-derived time in range (TIR) and glucose variability (GV) in patients with T1D and functioning pancreatic grafts after SPKT. Fifty-four CGM recordings from 43 patients, 15 men and 28 women, aged 34 (31; 39) years were analyzed. Time since SKPT was up to 1 year (group 1, n = 13), from 1 to 5 years (group 2, n = 15), and from 5 to 12 years (group 3, n = 26). TIR (3.9\u201310 mmol\/L), Time Above Range (TAR), Time Below Range (TBR), and GV parameters were estimated. There were no differences in mean glucose (5.5 [5.1; 6.2], 5.9 [5.4; 6.2], and 5.9 [5.6; 6.7] mmol\/L), TIR (97.6 [92.8\u201399.1], 97.2 [93.2; 99.1], and 97.5 [93.4; 99]%); TAR (0, 1.8 [1.3; 3.7], and 2.5 [2; 5]%), TBR (5 [3.3; 12.7], 4.1 [2.2; 10.1], and 3.5 [1.3; 6.5]%) and GV parameters between three groups (all p &gt; 0.05). Thus, recipients with functioning pancreatic grafts demonstrate remarkably high TIR and low GV after SPKT.<\/jats:p>","DOI":"10.3390\/diagnostics13091606","type":"journal-article","created":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T12:08:31Z","timestamp":1682942911000},"page":"1606","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Continuous Glucose Monitoring in Patients Following Simultaneous Pancreas\u2013Kidney Transplantation: Time in Range and Glucose Variability"],"prefix":"10.3390","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5731-3310","authenticated-orcid":false,"given":"Ilya V.","family":"Dmitriev","sequence":"first","affiliation":[{"name":"Sklifosovsky Research Institute for Emergency Medicine, 129090 Moscow, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anastasia S.","family":"Severina","sequence":"additional","affiliation":[{"name":"Endocrinology Research Center, 117292 Moscow, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0156-2107","authenticated-orcid":false,"given":"Nikita S.","family":"Zhuravel","sequence":"additional","affiliation":[{"name":"Sklifosovsky Research Institute for Emergency Medicine, 129090 Moscow, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Madina I.","family":"Yevloyeva","sequence":"additional","affiliation":[{"name":"Endocrinology Research Center, 117292 Moscow, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8694-9679","authenticated-orcid":false,"given":"Rustam K.","family":"Salimkhanov","sequence":"additional","affiliation":[{"name":"Endocrinology Research Center, 117292 Moscow, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3292-8949","authenticated-orcid":false,"given":"Svetlana P.","family":"Shchelykalina","sequence":"additional","affiliation":[{"name":"Department of Medical Cybernetics and Computer Science MBF Pirogov Russian National Research Medical University (RNRMU), 117997 Moscow, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Evgeniy A.","family":"Bezunov","sequence":"additional","affiliation":[{"name":"FSBI \u201cCentral Clinical Hospital with Polyclinic\u201d of the Presidential Department of the Russian Federation, 121359 Moscow, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Minara S.","family":"Shamkhalova","sequence":"additional","affiliation":[{"name":"Endocrinology Research Center, 117292 Moscow, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julia F.","family":"Semenova","sequence":"additional","affiliation":[{"name":"Research Institute of Clinical and Experimental Lymphology\u2014Branch of the Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences (RICEL\u2014Branch of IC&G SB RAS), 630060 Novosibirsk, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vadim V.","family":"Klimontov","sequence":"additional","affiliation":[{"name":"Research Institute of Clinical and Experimental Lymphology\u2014Branch of the Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences (RICEL\u2014Branch of IC&G SB RAS), 630060 Novosibirsk, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marina V.","family":"Shestakova","sequence":"additional","affiliation":[{"name":"Endocrinology Research Center, 117292 Moscow, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,4,30]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"614","DOI":"10.1210\/clinem\/dgac644","article-title":"Pancreas Transplantation: Current Challenges, Considerations, and Controversies","volume":"108","author":"Fridell","year":"2023","journal-title":"J. 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