{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T07:16:35Z","timestamp":1761808595357,"version":"build-2065373602"},"reference-count":33,"publisher":"MDPI AG","issue":"9","license":[{"start":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T00:00:00Z","timestamp":1682899200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"State Key Laboratory of Ultrasound in Medicine and Engineering","award":["2020KFKT009"],"award-info":[{"award-number":["2020KFKT009"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostics"],"abstract":"<jats:p>Cystic adenomyosis is a rare type of uterine adenomyosis, mainly seen in young women, which is often characterized by severe dysmenorrhea. The quality of life and reproductive function of young women could be affected by misdiagnosis and delayed treatment. At present, there are no universal guidelines and consensus. We report two cases of patients with cystic adenomyosis in juveniles treated with high-intensity focused ultrasound (HIFU) ablation. In the first case, magnetic resonance imaging (MRI) indicated a cystic mass of 2.0 cm \u00d7 3.1 cm \u00d7 2.4 cm in the uterus. After she underwent HIFU treatment, her pelvic MRI showed a mass of 1.1 \u00d7 2.4 cm in size, and her dysmenorrhea symptoms gradually disappeared. In the second case, a pelvic MRI indicated a 5.1 cm \u00d7 3.3 cm \u00d7 4.7 cm cystic mass in the uterus. After she underwent HIFU and combined four consecutive cycles of GnRH-a treatment, the lesion shrunk 1.2 cm \u00d71.4 cm \u00d7 1.6 cm, without dysmenorrhea. Simultaneously, the report reviewed 14 cases of juvenile cystic adenomyosis over the last ten years. HIFU or HIFU-combined drugs were safe and effective in treating juvenile cystic adenomyosis, but multicenter and prospective studies may be necessary to validate this in the future.<\/jats:p>","DOI":"10.3390\/diagnostics13091608","type":"journal-article","created":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T12:08:31Z","timestamp":1682942911000},"page":"1608","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["High Intensity Focused Ultrasound Ablation for Juvenile Cystic Adenomyosis: Two Case Reports and Literature Review"],"prefix":"10.3390","volume":"13","author":[{"given":"Xin","family":"Liu","sequence":"first","affiliation":[{"name":"School of Medical and Life Science, Chengdu University of Traditional Chinese Medicine, Chengdu 610000, China"},{"name":"Department of Gynecology, Suining Central Hospital, Suining 629000, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jingxi","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Gynecology, Suining Central Hospital, Suining 629000, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yanglu","family":"Liu","sequence":"additional","affiliation":[{"name":"School of Medical and Life Science, Chengdu University of Traditional Chinese Medicine, Chengdu 610000, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shuang","family":"Luo","sequence":"additional","affiliation":[{"name":"Department of Gynecology, Suining Central Hospital, Suining 629000, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0622-1678","authenticated-orcid":false,"given":"Gaowu","family":"Yan","sequence":"additional","affiliation":[{"name":"Department of Radiology and Imaging, Suining Central Hospital, Suining 629000, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huaqi","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Gynecology, Suining Central Hospital, Suining 629000, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lili","family":"Wan","sequence":"additional","affiliation":[{"name":"Department of Gynecology, Suining Central Hospital, Suining 629000, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guohua","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Gynecology, Suining Central Hospital, Suining 629000, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2023,5,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1002\/uog.24786","article-title":"Consensus on revised definitions of Morphological Uterus Sonographic Assessment (MUSA) features of adenomyosis: Results of modified Delphi procedure","volume":"60","author":"Harmsen","year":"2022","journal-title":"Ultrasound Obstet. 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