{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T04:44:28Z","timestamp":1787805868299,"version":"build-2784847793"},"reference-count":115,"publisher":"MDPI AG","issue":"11","license":[{"start":{"date-parts":[[2023,5,23]],"date-time":"2023-05-23T00:00:00Z","timestamp":1684800000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostics"],"abstract":"<jats:p>Objective: the purpose of this review was to evaluate the prevalence of appendiceal endometriosis and the safety of concomitant appendectomy in women with endometriosis or pelvic pain. Materials and Methods: We searched the electronic databases Medline (PubMed), Scopus, Embase, and Web of Science (WOS). The search was not subject to any limitation in terms of time or method. The primary research question was: what is the prevalence of appendiceal endometriosis? The secondary research question was: is it safe to perform appendectomy during surgery for endometriosis? Publications that reported data about appendiceal endometriosis or appendectomy in women with endometriosis were reviewed regarding the inclusion criteria. Results: We found 1418 records. After review and screening, we included 75 studies published between 1975 and 2021. With regard to the first question of the review, we found 65 eligible studies and divided these into the following two categories: (a) endometriosis of the appendix presenting as acute appendicitis, and (b) endometriosis of the appendix as an incidental finding in gynecological surgery. Forty-four case reports described appendiceal endometriosis in women who were admitted for the treatment of pain in the right-sided lower abdomen. Endometriosis of the appendix was observed in 2.67% (range, 0.36\u201323%) of women who were admitted due to acute appendicitis. In addition, appendiceal endometriosis was an incidental finding during gynecological surgery in 7.23% of cases (range, 1\u201344.3%). With regard to the second question of the review, which was the safety of appendectomy in women with endometriosis or pelvic pain, we found 11 eligible studies. Reviewed cases had no significant intraoperative or follow-up complications during the 12 weeks. Conclusion: Based on the reviewed studies, coincidental appendectomy appears reasonably safe and was associated with no complications in the cases reviewed for the present report.<\/jats:p>","DOI":"10.3390\/diagnostics13111827","type":"journal-article","created":{"date-parts":[[2023,5,23]],"date-time":"2023-05-23T07:00:02Z","timestamp":1684825202000},"page":"1827","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":37,"title":["Appendiceal Endometriosis: A Comprehensive Review of the Literature"],"prefix":"10.3390","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9851-6771","authenticated-orcid":false,"given":"Leila","family":"Allahqoli","sequence":"first","affiliation":[{"name":"Ministry of Health and Medical Education, Tehran 1467664961, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Afrooz","family":"Mazidimoradi","sequence":"additional","affiliation":[{"name":"Student Research Committee, Shiraz University of Medical Sciences, Shiraz 7134814336, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zohre","family":"Momenimovahed","sequence":"additional","affiliation":[{"name":"Department of Midwifery and Reproductive Health, Qom University of Medical Sciences, Qom 3716993456, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Veronika","family":"G\u00fcnther","sequence":"additional","affiliation":[{"name":"University Hospitals Schleswig-Holstein, Kiel School of Gynaecological Endoscopy, Campus Kiel, Arnold-Heller-Str. 3, Haus 24, 24105 Kiel, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johannes","family":"Ackermann","sequence":"additional","affiliation":[{"name":"University Hospitals Schleswig-Holstein, Kiel School of Gynaecological Endoscopy, Campus Kiel, Arnold-Heller-Str. 3, Haus 24, 24105 Kiel, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hamid","family":"Salehiniya","sequence":"additional","affiliation":[{"name":"Social Determinants of Health Research Center, Birjand University of Medical Sciences, Birjand 9717853577, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7194-6034","authenticated-orcid":false,"given":"Ibrahim","family":"Alkatout","sequence":"additional","affiliation":[{"name":"University Hospitals Schleswig-Holstein, Kiel School of Gynaecological Endoscopy, Campus Kiel, Arnold-Heller-Str. 3, Haus 24, 24105 Kiel, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,5,23]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1849","DOI":"10.1016\/j.jmig.2021.08.032","article-title":"An International Terminology for Endometriosis, 2021","volume":"28","author":"Tomassetti","year":"2021","journal-title":"J. Minim. Invasive Gynecol."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1007\/s13669-017-0187-1","article-title":"Endometriosis: Epidemiology, Diagnosis and Clinical Management","volume":"6","author":"Parasar","year":"2017","journal-title":"Curr. Obstet. Gynecol. Rep."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1007\/s00464-004-8710-7","article-title":"Laparoscopic colorectal resection for endometriosis","volume":"19","author":"Campagnacci","year":"2005","journal-title":"Surg. Endosc."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1016\/S0015-0282(99)00211-3","article-title":"Ovarian endometriosis: A marker for more extensive pelvic and intestinal disease","volume":"72","author":"Redwine","year":"1999","journal-title":"Fertil. Steril."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1067\/j.cpradiol.2011.01.003","article-title":"Beyond the boundaries-endometriosis: Typical and atypical locations","volume":"40","author":"Sonavane","year":"2011","journal-title":"Curr. Probl. Diagn. Radiol."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"758","DOI":"10.1111\/j.1445-2197.2007.04232.x","article-title":"Intussusception of the veriform appendix due to endometriosis presenting as acute appendicitis","volume":"77","author":"Moradi","year":"2007","journal-title":"ANZ J. Surg."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"536","DOI":"10.1016\/S1074-3804(05)60617-2","article-title":"Appendiceal disease in women with endometriosis and right lower quadrant pain","volume":"8","author":"Harris","year":"2001","journal-title":"J. Am. Assoc. Gynecol. Laparosc."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1007\/s12262-016-1557-z","article-title":"Incidental findings in routine histopathological examination of appendectomy specimens; retrospective analysis of 1970 patients","volume":"80","author":"Dincel","year":"2018","journal-title":"Indian J. Surg."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"979","DOI":"10.1016\/j.jogc.2016.06.006","article-title":"Isolated appendiceal endometriosis","volume":"38","author":"Shen","year":"2016","journal-title":"J. Obstet. Gynaecol. Can."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1177\/1066896918784650","article-title":"Unusual histopathological findings in appendectomy specimens: A retrospective analysis of 2047 cases","volume":"27","author":"Unver","year":"2019","journal-title":"Int. J. Surg. Pathol."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/j.ijsu.2019.10.025","article-title":"Communication and management of incidental pathology in 1214 consecutive appendicectomies; a cohort study","volume":"72","author":"Kinnear","year":"2019","journal-title":"Int. J. Surg."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1016\/j.jmig.2019.02.015","article-title":"Endometriosis of the appendix: When to predict and how to manage\u2014A multivariate analysis of 1935 endometriosis cases","volume":"27","author":"Mabrouk","year":"2020","journal-title":"J. Minim. Invasive Gynecol."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1002\/ijgo.12286","article-title":"Risk of appendiceal endometriosis among women with deep-infiltrating endometriosis","volume":"139","author":"Moulder","year":"2017","journal-title":"Int. J. Gynecol. Obstet."},{"key":"ref_14","first-page":"20","article-title":"Endometriosis of the appendix and cecum associated with acute appendicitis","volume":"69","author":"Thiel","year":"1986","journal-title":"Minn. Med."},{"key":"ref_15","first-page":"435","article-title":"Endometriosis of the appendix presenting as acute appendicitis","volume":"45","author":"Khoo","year":"2004","journal-title":"Singap. Med. J."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1001\/archsurg.1951.01250040631007","article-title":"Endometriosis of the vermiform appendix: Review of literature, with addition of nine new instances, one of which caused severe melena","volume":"63","author":"COLLINS","year":"1951","journal-title":"AMA Arch. Surg."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1016\/j.fertnstert.2005.12.076","article-title":"Endometriosis and the appendix: A case series and comprehensive review of the literature","volume":"86","author":"Gustofson","year":"2006","journal-title":"Fertil. Steril."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1007\/s00404-008-0570-2","article-title":"Appendiceal endometriosis: Two case reports","volume":"278","author":"Uncu","year":"2008","journal-title":"Arch. Gynecol. Obstet."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"1147","DOI":"10.1007\/s00384-019-03242-0","article-title":"Appendiceal endometriosis invading the sigmoid colon: A rare entity","volume":"34","author":"Lainas","year":"2019","journal-title":"Int. J. Color. Dis."},{"key":"ref_20","doi-asserted-by":"crossref","unstructured":"Teiga, E., Radosevic, A., S\u00e1nchez, J., Busto, M., Aguilar, G., Maiques, J., Flores, D., Zugazaga, A., Beltran, J.G., and Baz\u00e1n, F. (2019). A rare case of right lower quadrant pain. BJR Case Rep., 5.","DOI":"10.1259\/bjrcr.20170024"},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1111\/j.1471-0528.1981.tb01014.x","article-title":"Perforation of the appendix during pregnancy; a rare complication of endometriosis: Case report","volume":"88","author":"Gini","year":"1981","journal-title":"BJOG Int. J. Obstet. Gynaecol."},{"key":"ref_22","first-page":"e5816","article-title":"Endometriosis of the Vermiform Appendix Presenting as Acute Appendicitis","volume":"11","author":"Adeboye","year":"2019","journal-title":"Cureus"},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1097\/GRF.0000000000000291","article-title":"Surgery and Endometriosis","volume":"60","author":"Zanelotti","year":"2017","journal-title":"Clin. Obstet. Gynecol."},{"key":"ref_24","first-page":"Cd011031","article-title":"Laparoscopic surgery for endometriosis","volume":"10","author":"Bafort","year":"2020","journal-title":"Cochrane Database Syst. Rev."},{"key":"ref_25","doi-asserted-by":"crossref","unstructured":"Duffy, J.M.N., Arambage, K., Correa, F.J.S., Olive, D., Farquhar, C., Garry, R., Barlow, D.H., and Jacobson, T.Z. (2014). Laparoscopic surgery for endometriosis. Cochrane Database Syst. Rev.","DOI":"10.1002\/14651858.CD011031.pub2"},{"key":"ref_26","doi-asserted-by":"crossref","unstructured":"Drumond, J.P.N., de Melo, A.L.A., Germini, D.E., and Morrell, A.C. (2020). Acute Appendicitis Secondary to Appendiceal Endometriosis. Case Rep. Surg., 2020.","DOI":"10.1155\/2020\/8813184"},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1097\/AOG.0000000000005033","article-title":"Postoperative Complications of Appendectomy in Gynecologic Laparoscopic Surgery for Benign Indications","volume":"141","author":"Gupta","year":"2023","journal-title":"Obstet. Gynecol."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1097\/GCO.0000000000000466","article-title":"The role of appendectomy at the time of laparoscopic surgery for benign gynecologic conditions","volume":"30","author":"Peters","year":"2018","journal-title":"Curr. Opin. Obstet. Gynecol."},{"key":"ref_29","first-page":"647","article-title":"Incidental Appendectomy: Benefits at the Time of Total Abdominal Hysterectomy","volume":"19","author":"Ahmad","year":"2012","journal-title":"Prof. Med. J."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/2046-4053-4-1","article-title":"Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015 statement","volume":"4","author":"Moher","year":"2015","journal-title":"Syst. Rev."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"105605","DOI":"10.1016\/j.ijscr.2021.01.099","article-title":"Ectopic endometriosis, menstruation, and acute appendicitis: A thought-provoking case","volume":"80","author":"Hori","year":"2021","journal-title":"Int. J. Surg. Case Rep."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1080\/20009666.2020.1821469","article-title":"Abdominal pain\u2014A common presentation with unusual diagnosis: A case report","volume":"10","author":"Reddy","year":"2020","journal-title":"J. Community Hosp. Intern. Med. Perspect."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"1528","DOI":"10.1177\/0003134820933606","article-title":"Appendiceal Endometriosis Presenting as Possible Cecal Mass","volume":"86","author":"Feldhaus","year":"2020","journal-title":"Am. Surg."},{"key":"ref_34","first-page":"179","article-title":"Endometriosis apendicular. Reporte de caso","volume":"35","author":"Perrone","year":"2019","journal-title":"Rev. M\u00e9dica Del Urug."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"492","DOI":"10.12809\/hkmj187654","article-title":"Appendiceal endometriosis: A greater mimicker of appendicitis","volume":"25","author":"Jeong","year":"2019","journal-title":"Hong Kong Med. J."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1016\/j.ijscr.2019.07.046","article-title":"Appendicular endometriosis: A case report and review of literature","volume":"64","author":"Gupta","year":"2019","journal-title":"Int. J. Surg. Case Rep."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1093\/omcr\/omy099","article-title":"Isolated appendiceal endometriosis resulting in intussusception","volume":"2018","author":"Manoharan","year":"2018","journal-title":"Oxf. Med. Case Rep."},{"key":"ref_38","first-page":"309","article-title":"The case of the missing appendix: A case report of appendiceal intussusception at the site of colonic mullerianosis","volume":"5","author":"Quirante","year":"2017","journal-title":"Gastroenterol. Rep."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"33","DOI":"10.7196\/sajog.995","article-title":"Endometriosis of the meso-appendix mimicking appendicitis: A case report","volume":"22","author":"Ramkelawon","year":"2016","journal-title":"S. Afr. J. Obstet. Gynaecol."},{"key":"ref_40","first-page":"141","article-title":"Endometriosis masquerading as appendicitis","volume":"26","author":"Wang","year":"2006","journal-title":"J. Med. Sci."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1007\/s00384-014-1987-7","article-title":"Chronic appendicitis secondary to endometriosis: A case report","volume":"30","author":"Huang","year":"2015","journal-title":"Int. J. Color. Dis."},{"key":"ref_42","first-page":"bcr2014207584","article-title":"Intussusception of the vermiform appendix","volume":"2015","author":"Ibrahim","year":"2015","journal-title":"BMJ Case Rep."},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"34","DOI":"10.5301\/JE.2013.11017","article-title":"Endometriosis of the appendix: The experience of general surgeons in a large teaching hospital","volume":"5","author":"Ward","year":"2013","journal-title":"J. Endometr. Pelvic Pain Disord."},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/j.ijscr.2012.07.018","article-title":"An unusual cause of acute appendicitis: Appendiceal endometriosis","volume":"4","author":"Emre","year":"2013","journal-title":"Int. J. Surg. Case Rep."},{"key":"ref_45","first-page":"369","article-title":"Laparoscopic appendectomy for appendiceal endometriosis presenting as acute appendicitis","volume":"91","author":"Zaafouri","year":"2013","journal-title":"La Tunis. Med."},{"key":"ref_46","first-page":"69","article-title":"Endometriosis of the appendix presenting as acute appendicitis: A case report and literature review","volume":"23","author":"Uwaezuoke","year":"2013","journal-title":"Ethiop. J. Health Sci."},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1089\/gyn.2011.0021","article-title":"Endometriosis of the appendix: Incidental diagnosis","volume":"28","author":"Malhotra","year":"2012","journal-title":"J. Gynecol. Surg."},{"key":"ref_48","first-page":"304","article-title":"Endometriosis: A rare cause of appendicitis","volume":"21","author":"Salati","year":"2011","journal-title":"J. Coll. Physicians Surg. Pak."},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1186\/1752-1947-5-144","article-title":"Acute appendicitis caused by endometriosis: A case report","volume":"5","author":"Laskou","year":"2011","journal-title":"J. Med. Case Rep."},{"key":"ref_50","first-page":"39","article-title":"A case of endometriosis of the appendix","volume":"59","author":"Tazaki","year":"2010","journal-title":"Hiroshima J. Med. Sci."},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"1170","DOI":"10.5833\/jjgs.43.1170","article-title":"A case of appendiceal endometriosis occurring 13 years after hysterectomy with bilateral adnexectomy","volume":"43","author":"Sato","year":"2010","journal-title":"Jpn. J. Gastroenterol. Surg."},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"642","DOI":"10.1016\/j.gcb.2010.07.014","article-title":"Endometriosis of the appendix presenting as acute appendicitis: Report of a case","volume":"34","author":"Maghrebi","year":"2010","journal-title":"Gastroenterol. Clin. Biol."},{"key":"ref_53","first-page":"1610","article-title":"Appendiceal endometriosis differentially diagnosed from acute appendicitis","volume":"123","author":"Astroza","year":"2010","journal-title":"Chin. Med. J."},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"e66","DOI":"10.1016\/j.amjsurg.2008.04.024","article-title":"Endometriosis-induced appendiceal intussusception","volume":"197","author":"Liang","year":"2009","journal-title":"Am. J. Surg."},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1007\/s00404-008-0660-1","article-title":"A rare case of coexistence of carcinoid tumor of appendix vermicularis and ileal endometriosis","volume":"279","author":"Azordegan","year":"2009","journal-title":"Arch. Gynecol. Obstet."},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1007\/s00404-008-0922-y","article-title":"Appendiceal endometriosis presenting as perforated appendicitis: Report of a case and review of the literature","volume":"280","author":"Akbulut","year":"2009","journal-title":"Arch. Gynecol. Obstet."},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1007\/s00595-006-3440-1","article-title":"Laparoscopic appendectomy for appendiceal endometriosis presenting as acute appendicitis: Report of a case","volume":"37","author":"Idetsu","year":"2007","journal-title":"Surg. Today"},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1159\/000104223","article-title":"Endometriosis of the appendix resulting in perforated appendicitis","volume":"1","author":"Hasegawa","year":"2007","journal-title":"Case Rep. Gastroenterol."},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1055\/s-2006-955969","article-title":"Deciduosis and endometriosis of the appendix causing acute nonbacterial appendicitis","volume":"67","author":"Bohlmann","year":"2007","journal-title":"Geburtshilfe Und Frauenheilkd."},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"712","DOI":"10.1080\/00015458.2006.11679989","article-title":"Appendiceal endometriosis mimicking acute appendicitis","volume":"106","author":"Tumay","year":"2006","journal-title":"Acta Chir. Belg."},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"277","DOI":"10.5833\/jjgs.34.277","article-title":"A case of intestinal obstruction caused by endometoriosis of the ileum","volume":"34","author":"Shinohara","year":"2001","journal-title":"Jpn. J. Gastroenterol. Surg."},{"key":"ref_62","doi-asserted-by":"crossref","first-page":"860","DOI":"10.1309\/EUTL-BC88-TLAX-1UJ4","article-title":"Mucocele of the appendix secondary to endometriosis. Report of two cases, one with localized pseudomyxoma peritonei","volume":"113","author":"Driman","year":"2000","journal-title":"Am. J. Clin. Pathol."},{"key":"ref_63","first-page":"427","article-title":"Endometriosis of the vermiform appendix (EVA) is an uncommon lesion with a frequency < 1% of all cases of pelvic endometriosis. Recent case","volume":"23","year":"1999","journal-title":"World J. Surg."},{"key":"ref_64","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1007\/BF02482989","article-title":"Intussusception of a mucocele of the appendix secondary to an obstruction by endometriosis: Report of a case","volume":"29","author":"Kimura","year":"1999","journal-title":"Surg. Today"},{"key":"ref_65","first-page":"1881","article-title":"Appendiceal endometriosis presenting as massive lower intestinal hemorrhage","volume":"90","author":"Shome","year":"1995","journal-title":"Am. J. Gastroenterol."},{"key":"ref_66","doi-asserted-by":"crossref","first-page":"833","DOI":"10.1097\/00007611-199408000-00017","article-title":"Retention mucocele of appendix due to endometriosis","volume":"87","author":"Nopajaroonsri","year":"1994","journal-title":"South. Med. J."},{"key":"ref_67","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1097\/00004836-199306000-00021","article-title":"Endometriosis of the appendix resulting in perforation: A case report","volume":"16","author":"Yelon","year":"1993","journal-title":"J. Clin. Gastroenterol."},{"key":"ref_68","doi-asserted-by":"crossref","first-page":"1928","DOI":"10.5833\/jjgs.23.1928","article-title":"A Case of Endometriosis of the Appendix Presenting as Acute Appendicitis","volume":"23","author":"Fujisawa","year":"1988","journal-title":"Jpn. J. Gastroenterol. Surg."},{"key":"ref_69","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1016\/0002-9378(75)90026-5","article-title":"Endometriosis of the appendix. Report of twelve cases and review of the literature","volume":"121","author":"Uohara","year":"1975","journal-title":"Am. J. Obstet. Gynecol."},{"key":"ref_70","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1016\/j.rbmo.2020.06.008","article-title":"Emergency surgery for appendectomy and incidental diagnosis of superficial peritoneal endometriosis in fertile age women","volume":"41","author":"Coratti","year":"2020","journal-title":"Reprod. Biomed. Online"},{"key":"ref_71","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.humpath.2019.08.004","article-title":"Clinicopathologic findings in gynecologic proliferations of the appendix","volume":"92","author":"Noor","year":"2019","journal-title":"Hum. Pathol."},{"key":"ref_72","doi-asserted-by":"crossref","first-page":"117","DOI":"10.22159\/ajpcr.2018.v11i7.25432","article-title":"Surveillance of appendicectomy specimen with histomorphological evaluation","volume":"11","author":"Baisakh","year":"2018","journal-title":"Asian J. Pharm. Clin. Res."},{"key":"ref_73","first-page":"519","article-title":"Unexpected findings in the routine histopathological examinations of appendectomy specimens A retrospective analysis of 1970 patients","volume":"88","author":"Dincel","year":"2017","journal-title":"Ann. Ital. Di Chir."},{"key":"ref_74","doi-asserted-by":"crossref","first-page":"1285","DOI":"10.1007\/s12262-015-1278-8","article-title":"Unexpected Histopathological Findings in Appendectomy Specimens: A Retrospective Study of 1627 Cases","volume":"77","author":"Limaiem","year":"2015","journal-title":"Indian J. Surg."},{"key":"ref_75","doi-asserted-by":"crossref","first-page":"354","DOI":"10.9738\/INTSURG-D-13-00098.1","article-title":"Routine histopathologic examination of appendectomy specimens: Retrospective analysis of 1255 patients","volume":"98","author":"Emre","year":"2013","journal-title":"Int. Surg."},{"key":"ref_76","first-page":"728","article-title":"Acute appendicitis and endometriosis: Retrospective analysis in emergency setting","volume":"35","author":"Agrusa","year":"2013","journal-title":"G. Ital. Di Ostet. E Ginecol."},{"key":"ref_77","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1159\/000317270","article-title":"Appendectomy in the gynecological setting: Intraoperative findings and corresponding histopathology","volume":"71","author":"Shavell","year":"2011","journal-title":"Gynecol. Obstet. Investig."},{"key":"ref_78","doi-asserted-by":"crossref","first-page":"808","DOI":"10.1177\/000313481007600822","article-title":"The incidence of benign and malignant neoplasia presenting as acute appendicitis","volume":"76","author":"Sieren","year":"2010","journal-title":"Am. Surg."},{"key":"ref_79","first-page":"253","article-title":"Endometriosis of the vermiform appendix","volume":"91","author":"Nielsen","year":"1983","journal-title":"Acta Pathol. Microbiol. Immunol. Scandinavica. Sect. A Pathol."},{"key":"ref_80","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1016\/j.jmig.2005.03.003","article-title":"Laparoscopic appendectomy in patients with endometriosis","volume":"12","author":"Berker","year":"2005","journal-title":"J. Minim. Invasive Gynecol."},{"key":"ref_81","doi-asserted-by":"crossref","first-page":"526","DOI":"10.1002\/ijgo.13614","article-title":"Appendectomy in the surgical management of women with endometriosis and pelvic pain","volume":"154","author":"Ross","year":"2021","journal-title":"Int. J. Gynaecol. Obstet. Off. Organ Int. Fed. Gynaecol. Obstet."},{"key":"ref_82","doi-asserted-by":"crossref","first-page":"1531","DOI":"10.1016\/j.jmig.2020.01.009","article-title":"Appendiceal Endometriosis: Is Diagnosis Dependent on Pathology Evaluation? A Prospective Cohort Study","volume":"27","author":"Ross","year":"2020","journal-title":"J. Minim. Invasive Gynecol."},{"key":"ref_83","first-page":"421","article-title":"Appendectomy in the surgical treatment of endometriosis","volume":"61","author":"Pittaway","year":"1983","journal-title":"Obstet. Gynecol."},{"key":"ref_84","doi-asserted-by":"crossref","first-page":"e2020.00095","DOI":"10.4293\/JSLS.2020.00095","article-title":"Appendectomy Should Be Performed During Minimally Invasive Surgery for Endometriosis","volume":"25","author":"Nikou","year":"2021","journal-title":"JSLS J. Soc. Laparoendosc. Surg."},{"key":"ref_85","first-page":"386","article-title":"Incidental appendectomy at the time of gynecologic surgery","volume":"39","author":"Benoit","year":"2018","journal-title":"Eur. J. Gynaecol. Oncol."},{"key":"ref_86","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1089\/gyn.2016.0123","article-title":"Appendectomy at Gynecologic Surgery: Feasibility and Outcomes in a High Risk Gynecologic Population-Revealing a High Rate of Incidental Appendiceal Cancer","volume":"33","author":"Benoit","year":"2017","journal-title":"J. Gynecol. Surg."},{"key":"ref_87","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1016\/S1701-2163(15)31047-1","article-title":"The role of appendectomy in gynaecologic surgery: A canadian retrospective case series","volume":"35","author":"Jocko","year":"2013","journal-title":"J. Obstet. Gynaecol. Can."},{"key":"ref_88","doi-asserted-by":"crossref","first-page":"1099","DOI":"10.1016\/j.fertnstert.2009.10.031","article-title":"Endometriosis at several sites, cyclic bowel symptoms, and the likelihood of the appendix being affected","volume":"94","author":"Rodini","year":"2010","journal-title":"Fertil. Steril."},{"key":"ref_89","first-page":"376","article-title":"Incidental appendectomy during endoscopic surgery","volume":"13","author":"Song","year":"2009","journal-title":"JSLS J. Soc. Laparoendosc. Surg."},{"key":"ref_90","doi-asserted-by":"crossref","first-page":"1563","DOI":"10.1016\/S0002-9378(03)00936-0","article-title":"The safety of incidental appendectomy at the time of abdominal hysterectomy","volume":"189","author":"Salom","year":"2003","journal-title":"Am. J. Obstet. Gynecol."},{"key":"ref_91","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1016\/S1074-3804(05)60292-7","article-title":"Laparoscopic appendectomy","volume":"10","author":"Agarwala","year":"2003","journal-title":"J. Am. Assoc. Gynecol. Laparosc."},{"key":"ref_92","doi-asserted-by":"crossref","first-page":"542","DOI":"10.1016\/S1074-3804(05)60618-4","article-title":"Appendectomy in patients undergoing laparoscopic surgery for pelvic pain","volume":"8","author":"Lyons","year":"2001","journal-title":"J. Am. Assoc. Gynecol. Laparosc."},{"key":"ref_93","doi-asserted-by":"crossref","first-page":"S21","DOI":"10.1016\/S1074-3804(05)80938-7","article-title":"Laparoscopic Incidental Appendectomy: Prevention or Therapy?","volume":"1","author":"McTavish","year":"1994","journal-title":"J. Am. Assoc. Gynecol. Laparosc."},{"key":"ref_94","doi-asserted-by":"crossref","first-page":"82S","DOI":"10.1097\/01.AOG.0000483739.57586.30","article-title":"Appendectomy Performed Routinely in the Laparoscopic Treatment of Endometriosis: A Retrospective Analysis [5J]","volume":"127","author":"Mohling","year":"2016","journal-title":"Obstet. Gynecol."},{"key":"ref_95","doi-asserted-by":"crossref","first-page":"28.e21","DOI":"10.1016\/j.ajog.2010.08.042","article-title":"Laparoscopic incidental appendectomy during laparoscopic surgery for ovarian endometrioma","volume":"204","author":"Lee","year":"2011","journal-title":"Am. J. Obstet. Gynecol."},{"key":"ref_96","first-page":"1254","article-title":"The technique and the safety of laparoscopic incidental appendectomy using single loop duringgynecologic laparoscopic surgery","volume":"50","author":"Kim","year":"2007","journal-title":"Obstet. Gynecol. Sci."},{"key":"ref_97","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1001\/archsurg.1921.01110080003001","article-title":"Perforating hemorrhagic (chocolate) cysts of the ovary: Their importance and especially their relation to pelvic adenomas of endometrial type (adenomyoma of the uterus, rectovaginal septum, sigmoid, etc.)","volume":"3","author":"Sampson","year":"1921","journal-title":"Arch. Surg."},{"key":"ref_98","doi-asserted-by":"crossref","first-page":"855","DOI":"10.1001\/archsurg.1988.01400310069011","article-title":"Gastrointestinal endometriosis. Incidence and indications for resection","volume":"123","author":"Prystowsky","year":"1988","journal-title":"Arch. Surg."},{"key":"ref_99","first-page":"365","article-title":"Seventy-one thousand human appendix specimens: A final report summarizing 40-year study","volume":"14","author":"Collins","year":"1963","journal-title":"Am. J. Proctol."},{"key":"ref_100","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1002\/bjs.1800680218","article-title":"Endometriosis of the appendix","volume":"68","author":"Langman","year":"1981","journal-title":"J. Br. Surg."},{"key":"ref_101","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1007\/BF02589883","article-title":"Endometriosis of the intestines and vermiform appendix","volume":"15","author":"Panganiban","year":"1972","journal-title":"Dis. Colon Rectum"},{"key":"ref_102","doi-asserted-by":"crossref","first-page":"83","DOI":"10.4030\/jjcs1979.30.1_83","article-title":"A case of appendiceal endometriosis with intussusception","volume":"30","author":"Nishina","year":"2005","journal-title":"Nihon Gekakei Rengo Gakkaishi"},{"key":"ref_103","first-page":"60","article-title":"Combined treatment of endometriosis: Radical yet gentle","volume":"49","author":"Alkatout","year":"2018","journal-title":"Aktuelle Urol."},{"key":"ref_104","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1007\/s13224-014-0652-y","article-title":"Treatment of endometriosis in women desiring fertility","volume":"65","author":"Mavrelos","year":"2015","journal-title":"J. Obstet. Gynaecol. India"},{"key":"ref_105","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1097\/GCO.0000000000000483","article-title":"Advances in the management of endometriosis in the adolescent","volume":"30","author":"Mama","year":"2018","journal-title":"Curr. Opin. Obstet. Gynecol."},{"key":"ref_106","doi-asserted-by":"crossref","first-page":"5849","DOI":"10.3748\/wjg.v23.i32.5849","article-title":"Laparoscopic appendectomy for acute appendicitis: How to discourage surgeons using inadequate therapy","volume":"23","author":"Hori","year":"2017","journal-title":"World J. Gastroenterol."},{"key":"ref_107","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1097\/SLA.0000000000000560","article-title":"The NOTA Study (Non Operative Treatment for Acute Appendicitis): Prospective study on the efficacy and safety of antibiotics (amoxicillin and clavulanic acid) for treating patients with right lower quadrant abdominal pain and long-term follow-up of conservatively treated suspected appendicitis","volume":"260","author":"Sibilio","year":"2014","journal-title":"Ann. Surg."},{"key":"ref_108","doi-asserted-by":"crossref","first-page":"1785","DOI":"10.1002\/bjs.10660","article-title":"Randomized clinical trial of antibiotic therapy for uncomplicated appendicitis","volume":"104","author":"Park","year":"2017","journal-title":"J. Br. Surg."},{"key":"ref_109","doi-asserted-by":"crossref","first-page":"1022","DOI":"10.1007\/s00268-022-06446-8","article-title":"Efficacy and Safety of Non-Operative Management of Uncomplicated Acute Appendicitis Compared to Appendectomy: An Umbrella Review of Systematic Reviews and Meta-Analyses","volume":"46","author":"Emile","year":"2022","journal-title":"World J. Surg."},{"key":"ref_110","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1016\/j.ejrad.2017.11.020","article-title":"Clinical-radiological scoring system for enhanced diagnosis of acute appendicitis","volume":"98","author":"Mannil","year":"2018","journal-title":"Eur. J. Radiol."},{"key":"ref_111","doi-asserted-by":"crossref","first-page":"S769","DOI":"10.1016\/j.ajog.2019.12.037","article-title":"Coincidental appendectomy in the surgical management of women with endometriosis and pelvic pain","volume":"222","author":"Ross","year":"2020","journal-title":"Am. J. Obstet. Gynecol."},{"key":"ref_112","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1016\/0002-9378(95)90097-7","article-title":"The appendix as the cause of chronic lower abdominal pain","volume":"172","author":"Fayez","year":"1995","journal-title":"Am. J. Obstet. Gynecol."},{"key":"ref_113","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/S1074-3804(05)80007-6","article-title":"Prospective evaluation of laparoscopic appendectomy in women with chronic right lower quadrant pain","volume":"2","author":"AlSalilli","year":"1995","journal-title":"J. Am. Assoc. Gynecol. Laparosc."},{"key":"ref_114","doi-asserted-by":"crossref","first-page":"1285","DOI":"10.1097\/AOG.0b013e3181758ec6","article-title":"Surgical treatment of endometriosis: A 7-year follow-up on the requirement for further surgery","volume":"111","author":"Shakiba","year":"2008","journal-title":"Obstet. Gynecol."},{"key":"ref_115","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1016\/S0020-7292(97)00215-4","article-title":"Incidental appendectomy during gynecological surgery","volume":"59","author":"Lynch","year":"1997","journal-title":"Int. J. Gynaecol. Obstet. Off. Organ Int. Fed. Gynaecol. Obstet."}],"container-title":["Diagnostics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2075-4418\/13\/11\/1827\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T19:40:16Z","timestamp":1760125216000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2075-4418\/13\/11\/1827"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,5,23]]},"references-count":115,"journal-issue":{"issue":"11","published-online":{"date-parts":[[2023,6]]}},"alternative-id":["diagnostics13111827"],"URL":"https:\/\/doi.org\/10.3390\/diagnostics13111827","relation":{},"ISSN":["2075-4418"],"issn-type":[{"value":"2075-4418","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,5,23]]}}}