{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T21:11:44Z","timestamp":1784754704701,"version":"3.55.0"},"reference-count":35,"publisher":"MDPI AG","issue":"11","license":[{"start":{"date-parts":[[2023,5,27]],"date-time":"2023-05-27T00:00:00Z","timestamp":1685145600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Shin Kong Wu Ho-Su Memorial Hospital"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostics"],"abstract":"<jats:p>Although widely used, CT-guided lung nodule localization is associated with a significant risk of complications, including pneumothorax and pulmonary hemorrhage. This study identified potential risk factors affecting the complications associated with CT-guided lung nodule localization. Data from patients with lung nodules who underwent preoperative CT-guided localization with patent blue vital (PBV) dye at Shin Kong Wu Ho-Su Memorial Hospital, Taiwan, were retrospectively collected. Logistic regression analysis, the chi-square test, and the Mann\u2013Whitney test were used to analyze the potential risk factors for procedure-related complications. We included 101 patients with a single nodule (49 with pneumothorax and 28 with pulmonary hemorrhage). The results revealed that men were more susceptible to pneumothorax during CT-guided localization (odds ratio: 2.48, p = 0.04). Both deeper needle insertion depth (odds ratio: 1.84, p = 0.02) and nodules localized in the left lung lobe (odds ratio: 4.19, p = 0.03) were associated with an increased risk of pulmonary hemorrhage during CT-guided localization. In conclusion, for patients with a single nodule, considering the needle insertion depth and patient characteristics during CT-guided localization procedures is probably important for reducing the risk of complications.<\/jats:p>","DOI":"10.3390\/diagnostics13111881","type":"journal-article","created":{"date-parts":[[2023,5,27]],"date-time":"2023-05-27T16:16:04Z","timestamp":1685204164000},"page":"1881","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Complications during CT-Guided Lung Nodule Localization: Impact of Needle Insertion Depth and Patient Characteristics"],"prefix":"10.3390","volume":"13","author":[{"given":"Hua","family":"Chiang","sequence":"first","affiliation":[{"name":"Department of Diagnostic Radiology, Shin Kong Wu Ho-Su Memorial Hospital, Taipei 11101, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liang-Kuang","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Radiology, Shin Kong Wu Ho-Su Memorial Hospital, Taipei 11101, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wen-Pei","family":"Hsieh","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Radiology, Shin Kong Wu Ho-Su Memorial Hospital, Taipei 11101, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yun-Xuan","family":"Tang","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Radiology, Shin Kong Wu Ho-Su Memorial Hospital, Taipei 11101, Taiwan"},{"name":"Department of Medical Imaging and Radiological Technology, Yuanpei University of Medical Technology, Hsinchu 30015, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chun-Yu","family":"Lo","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Radiology, Shin Kong Wu Ho-Su Memorial Hospital, Taipei 11101, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,5,27]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"W678","DOI":"10.2214\/AJR.10.4659","article-title":"Complications of CT-guided percutaneous needle biopsy of the chest: Prevention and management","volume":"196","author":"Wu","year":"2011","journal-title":"AJR Am. 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