{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,6]],"date-time":"2026-06-06T22:29:29Z","timestamp":1780784969731,"version":"3.54.1"},"reference-count":31,"publisher":"MDPI AG","issue":"16","license":[{"start":{"date-parts":[[2023,8,10]],"date-time":"2023-08-10T00:00:00Z","timestamp":1691625600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Authorities for Social Welfare and for Science and Research, Hamburg, Germany","award":["LOM 2020"],"award-info":[{"award-number":["LOM 2020"]}]},{"name":"Authorities for Social Welfare and for Science and Research, Hamburg, Germany","award":["01KX2021"],"award-info":[{"award-number":["01KX2021"]}]},{"name":"Authorities for Social Welfare and for Science and Research, Hamburg, Germany","award":["01KX2121"],"award-info":[{"award-number":["01KX2121"]}]},{"name":"Institute of Legal Medicine Hamburg, Germany","award":["LOM 2020"],"award-info":[{"award-number":["LOM 2020"]}]},{"name":"Institute of Legal Medicine Hamburg, Germany","award":["01KX2021"],"award-info":[{"award-number":["01KX2021"]}]},{"name":"Institute of Legal Medicine Hamburg, Germany","award":["01KX2121"],"award-info":[{"award-number":["01KX2121"]}]},{"name":"German Federal Ministry of Education and Research","award":["LOM 2020"],"award-info":[{"award-number":["LOM 2020"]}]},{"name":"German Federal Ministry of Education and Research","award":["01KX2021"],"award-info":[{"award-number":["01KX2021"]}]},{"name":"German Federal Ministry of Education and Research","award":["01KX2121"],"award-info":[{"award-number":["01KX2121"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostics"],"abstract":"<jats:p>In the past years the number of hospital autopsies have declined steadily, becoming almost excluded from medical training. Medicolegal (forensic) autopsies account for almost all autopsies, whereas hospital autopsies are becoming increasingly rare. Minimally invasive tissue sampling (MITS) using post mortem ultrasound offers the opportunity to increase the number of post mortem examinations in a clinical and even forensic context. MITS is a needle-based post mortem procedure that uses (radiological) imaging techniques to examine major organs of the body, acquire tissue samples and aspirate fluid from the body cavities or hollow organs. In this study, MITS was used to determine the presence of other co-existing diseases in a deceased infected 97-year-old woman with severe acute respiratory syndrome coronavirus 2. The examination of her body was carried out using ultrasound as an imaging tool and to gather ultrasound-guided biopsies as conventional autopsy was rejected by the next of kin. Ultrasound and histology identified an intravesical mass leading to an obstruction of the urinary outlet resulting in bilateral hydronephrosis and purulent pyelonephritis, which was unknown during her lifetime. Histopathological examination revealed the tumor mass to be a squamous cell carcinoma. This study has shown that MITS can be used to determine the cause of death and the presence of concomitant diseases in the infectious deceased.<\/jats:p>","DOI":"10.3390\/diagnostics13162643","type":"journal-article","created":{"date-parts":[[2023,8,10]],"date-time":"2023-08-10T10:24:47Z","timestamp":1691663087000},"page":"2643","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Minimally Invasive Tissue Sampling via Post Mortem Ultrasound: A Feasible Tool (Not Only) in Infectious Diseases\u2014A Case Report"],"prefix":"10.3390","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5751-8076","authenticated-orcid":false,"given":"Akhator","family":"Terence Azeke","sequence":"first","affiliation":[{"name":"Department of Anatomic Pathology, Irrua Specialist Teaching Hospital, KM 87 Benin Auchi Rd, Irrua 310115, Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8197-7678","authenticated-orcid":false,"given":"Julia","family":"Sch\u00e4dler","sequence":"additional","affiliation":[{"name":"Institute of Legal Medicine, University Medical Center Hamburg-Eppendorf, Butenfeld 34, D-22529 Hamburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benjamin","family":"Ondruschka","sequence":"additional","affiliation":[{"name":"Institute of Legal Medicine, University Medical Center Hamburg-Eppendorf, Butenfeld 34, D-22529 Hamburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefan","family":"Steurer","sequence":"additional","affiliation":[{"name":"Institute of Pathology, University Medical Center Hamburg-Eppendorf, Martinistra\u00dfe 52, D-20246 Hamburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dustin","family":"M\u00f6bius","sequence":"additional","affiliation":[{"name":"Institute of Legal Medicine, University Medical Center Hamburg-Eppendorf, Butenfeld 34, D-22529 Hamburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonia","family":"Fitzek","sequence":"additional","affiliation":[{"name":"Institute of Legal Medicine, University Medical Center Hamburg-Eppendorf, Butenfeld 34, D-22529 Hamburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,8,10]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1148\/radiol.2018180924","article-title":"Conventional Autopsy versus Minimally Invasive Autopsy with Postmortem MRI, CT, and CT-guided Biopsy: Comparison of Diagnostic Performance","volume":"289","author":"Blokker","year":"2018","journal-title":"Radiology"},{"key":"ref_2","doi-asserted-by":"crossref","unstructured":"Rakislova, N., Marimon, L., Ismail, M.R., Carrilho, C., Fernandes, F., Ferrando, M., Castillo, P., Rodrigo-Calvo, M.T., Guerrero, J., and Ortiz, E. 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