{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T02:25:26Z","timestamp":1760149526037,"version":"build-2065373602"},"reference-count":10,"publisher":"MDPI AG","issue":"16","license":[{"start":{"date-parts":[[2023,8,13]],"date-time":"2023-08-13T00:00:00Z","timestamp":1691884800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Korea Health Technology R&amp;D Project","award":["HI22C0610"],"award-info":[{"award-number":["HI22C0610"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostics"],"abstract":"<jats:p>Cardiac angiosarcoma is a rare, malignant neoplasm affecting the heart. We present the clinical history of a 40-year-old patient diagnosed with metastatic angiosarcoma of the heart. The patient complained of shortness of breath, and a cardiac computed tomography scan revealed a mass in the right atrium and pericardial effusion. Transthoracic and transesophageal echocardiography provided detailed anatomical and functional information, and cardiac magnetic resonance imaging and fluorodeoxyglucose-positron emission tomography\/computed tomography were used to assess distant metastasis and characterize the mass in detail. Early differential diagnosis and comprehensive evaluation of a cardiac mass are vital for determining appropriate treatment strategies to improve patient outcomes. The pathological results from the endocardial biopsy confirmed the diagnosis of primary angiosarcoma. The patient underwent surgical resection of the right atrial mass but died within one month because of the locally advanced nature of the angiosarcoma and its rapid progression. The patient\u2019s medical journey sheds light on the challenges associated with diagnosing and treating this rare condition, particularly the rapid progression of its cardiac manifestations.<\/jats:p>","DOI":"10.3390\/diagnostics13162666","type":"journal-article","created":{"date-parts":[[2023,8,14]],"date-time":"2023-08-14T10:28:13Z","timestamp":1692008893000},"page":"2666","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Rapidly Progressive Metastatic Angiosarcoma of the Heart: A Case Report"],"prefix":"10.3390","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4313-1700","authenticated-orcid":false,"given":"Soo Yeon","family":"An","sequence":"first","affiliation":[{"name":"Department of Medical Sciences, College of Medicine, Chungnam National University, 266 Moonhwa-lo, Daejeon 35015, Republic of Korea"},{"name":"Division of Cardiology, Department of Internal Medicine, Chungnam National University Hospital, 282 Moonhwa-lo, Daejeon 35015, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Man-Shik","family":"Shim","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, Chungnam National University Hospital, 282 Moonhwa-lo, Daejeon 35015, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2023,8,13]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/S1470-2045(05)70093-0","article-title":"Cardiac tumours: Diagnosis and management","volume":"6","author":"Butany","year":"2005","journal-title":"Lancet Oncol."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"103","DOI":"10.12659\/MSM.889875","article-title":"Primary cardiac angiosarcoma\u2014A review","volume":"20","author":"Patel","year":"2014","journal-title":"Med. 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Surg."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"628","DOI":"10.4330\/wjc.v13.i11.628","article-title":"Cardiovascular magnetic resonance of cardiac tumors and masses","volume":"13","author":"Gatti","year":"2021","journal-title":"World J. Cardiol."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/j.jaccao.2020.05.009","article-title":"Cardiac tumors: JACC CardioOncology state-of-the-art review","volume":"2","author":"Tyebally","year":"2020","journal-title":"JACC CardioOncology"}],"container-title":["Diagnostics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2075-4418\/13\/16\/2666\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T20:32:39Z","timestamp":1760128359000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2075-4418\/13\/16\/2666"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,8,13]]},"references-count":10,"journal-issue":{"issue":"16","published-online":{"date-parts":[[2023,8]]}},"alternative-id":["diagnostics13162666"],"URL":"https:\/\/doi.org\/10.3390\/diagnostics13162666","relation":{},"ISSN":["2075-4418"],"issn-type":[{"type":"electronic","value":"2075-4418"}],"subject":[],"published":{"date-parts":[[2023,8,13]]}}}