{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,4]],"date-time":"2026-07-04T16:44:01Z","timestamp":1783183441945,"version":"3.54.6"},"reference-count":8,"publisher":"MDPI AG","issue":"20","license":[{"start":{"date-parts":[[2023,10,12]],"date-time":"2023-10-12T00:00:00Z","timestamp":1697068800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"VHS Medical Center Research","award":["VHSMC 23061"],"award-info":[{"award-number":["VHSMC 23061"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostics"],"abstract":"<jats:p>Histiocytic sarcoma (HS) is an extremely rare and aggressive malignant neoplasm of hematopoietic origin that shows morphologic and immunophenotypic evidence of histiocytic differentiation. In approximately 25% of the cases, presumed transdifferentiation of a preexisting hematolymphoid disorder can be demonstrated. Various extranodal sites, particularly the gastrointestinal tract, soft tissue, skin, and spleen, can be involved. Enhanced CT and FDG PET\/CT findings of extranodal histiocytic sarcoma have been barely reported. We present a case with extranodal HS originating in the small intestine after gastric large B-cell lymphoma, mistaken for prostate cancer metastasis in a 76-year-old man.<\/jats:p>","DOI":"10.3390\/diagnostics13203189","type":"journal-article","created":{"date-parts":[[2023,10,12]],"date-time":"2023-10-12T07:28:44Z","timestamp":1697095724000},"page":"3189","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Enhanced Computed Tomography and 18F-fluorodeoxyglucose Positron Emission Tomography\/Computed Tomography in the Uncommon Histiocytic Sarcoma of Small Intestine Arising after Gastric Large B-Cell Lymphoma"],"prefix":"10.3390","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7469-7769","authenticated-orcid":false,"given":"Miju","family":"Cheon","sequence":"first","affiliation":[{"name":"Department of Nuclear Medicine, Veterans Health Service Medical Center, Seoul 05368, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4664-4904","authenticated-orcid":false,"given":"Jang","family":"Yoo","sequence":"additional","affiliation":[{"name":"Department of Nuclear Medicine, Veterans Health Service Medical Center, Seoul 05368, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hae Su","family":"Kim","sequence":"additional","affiliation":[{"name":"Division of Hematology-Oncology, Department of Internal Medicine, Veterans Health Service Medical Center, Seoul 05368, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miji","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Pathology, Veterans Health Service Medical Center, Seoul 05368, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,10,12]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3960\/jslrt.53.1","article-title":"Histiocytic sarcoma: An updated literature review based on the 2008 WHO classification","volume":"53","author":"Takahashi","year":"2013","journal-title":"J. Clin. Exp. Hematop."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"225","DOI":"10.2350\/09-03-0622-OA.1","article-title":"Clinicopathologic features of histiocytic lesions following ALL, with a review of the literature","volume":"13","author":"Castro","year":"2010","journal-title":"Pediatr. Dev. Pathol."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"1133","DOI":"10.1097\/01.pas.0000131541.95394.23","article-title":"Extranodal histiocytic sarcoma: Clinicopathologic analysis of 14 cases of a rare epithelioid malignancy","volume":"28","author":"Hornick","year":"2004","journal-title":"Am. J. Surg. Pathol."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"844","DOI":"10.1093\/jjco\/hyaa267","article-title":"Histiocytic sarcoma with brainstem and spinal canal involvement detected by [18F]-FDG PET\/CT","volume":"51","year":"2021","journal-title":"Jpn. J. Clin. Oncol."},{"key":"ref_5","first-page":"263","article-title":"18F-FDG PET-CT in a multifocal peritoneal histiocytic sarcoma. A very rare case with complete response to second-line chemotherapy","volume":"40","year":"2021","journal-title":"Rev. Esp. Med. Nucl. Imagen. Mol."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1097\/RLU.0000000000001908","article-title":"Simultaneous Brain and Lung Histiocytic Sarcoma Revealed on 18F-FDG PET\/CT","volume":"43","author":"Pan","year":"2018","journal-title":"Clin. Nucl. Med."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1097\/RLU.0000000000001041","article-title":"Enhanced CT and FDG PET\/CT in Histiocytic Sarcoma of the Pericardium","volume":"41","author":"Dong","year":"2016","journal-title":"Clin. Nucl. Med."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"313","DOI":"10.3346\/jkms.2010.25.2.313","article-title":"A case of histiocytic sarcoma presenting with primary bone marrow involvement","volume":"25","author":"Sohn","year":"2010","journal-title":"J. Korean Med. Sci."}],"container-title":["Diagnostics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2075-4418\/13\/20\/3189\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T21:05:27Z","timestamp":1760130327000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2075-4418\/13\/20\/3189"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,10,12]]},"references-count":8,"journal-issue":{"issue":"20","published-online":{"date-parts":[[2023,10]]}},"alternative-id":["diagnostics13203189"],"URL":"https:\/\/doi.org\/10.3390\/diagnostics13203189","relation":{},"ISSN":["2075-4418"],"issn-type":[{"value":"2075-4418","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,10,12]]}}}