{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,14]],"date-time":"2026-01-14T16:49:38Z","timestamp":1768409378508,"version":"3.49.0"},"reference-count":39,"publisher":"MDPI AG","issue":"20","license":[{"start":{"date-parts":[[2023,10,13]],"date-time":"2023-10-13T00:00:00Z","timestamp":1697155200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostics"],"abstract":"<jats:p>Intravoxel incoherent motion (IVIM) and splenic volumetry (SV) for hepatic fibrosis (HF) prediction have been reported to be effective. Our purpose is to compare the HF prediction of IVIM and SV in 67 patients with pathologically staged HF. SV was divided by body surface area (BSA). IVIM indices, such as slow diffusion-coefficient related to molecular diffusion (D), fast diffusion-coefficient related to perfusion in microvessels (D*), apparent diffusion-coefficient (ADC), and perfusion related diffusion-fraction (f), were calculated by two observers (R1\/R2). D (p = 0.718 for R1, p = 0.087 for R2) and D* (p = 0.513, p = 0.708, respectively) showed a poor correlation with HF. ADC (p = 0.034, p = 0.528, respectively) and f (p &lt; 0.001, p = 0.007, respectively) decreased as HF progressed, whereas SV\/BSA increased (p = 0.015 for R1). The AUCs of SV\/BSA (0.649\u20130.698 for R1) were higher than those of f (0.575\u20130.683 for R1 + R2) for severe HF (\u2265F3\u20134 and \u2265F4), although AUCs of f (0.705\u20130.790 for R1 + R2) were higher than those of SV\/BSA (0.628 for R1) for mild or no HF (\u2264F0\u20131). No significant differences to identify HF were observed between IVIM and SV\/BSA. SV\/BSA allows a higher estimation for evaluating severe HF than IVIM. IVIM is more suitable than SV\/BSA for the assessment of mild or no HF.<\/jats:p>","DOI":"10.3390\/diagnostics13203200","type":"journal-article","created":{"date-parts":[[2023,10,13]],"date-time":"2023-10-13T06:07:26Z","timestamp":1697177246000},"page":"3200","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Comparison between Intravoxel Incoherent Motion and Splenic Volumetry to Predict Hepatic Fibrosis Staging in Preoperative Patients"],"prefix":"10.3390","volume":"13","author":[{"given":"Takayuki","family":"Arakane","sequence":"first","affiliation":[{"name":"Department of Radiology, Nihon University School of Medicine, Tokyo 173-8610, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6896-8419","authenticated-orcid":false,"given":"Masahiro","family":"Okada","sequence":"additional","affiliation":[{"name":"Department of Radiology, Nihon University School of Medicine, Tokyo 173-8610, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yujiro","family":"Nakazawa","sequence":"additional","affiliation":[{"name":"Department of Radiology, Nihon University School of Medicine, Tokyo 173-8610, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenichiro","family":"Tago","sequence":"additional","affiliation":[{"name":"Department of Radiology, Nihon University School of Medicine, Tokyo 173-8610, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroki","family":"Yoshikawa","sequence":"additional","affiliation":[{"name":"Department of Radiology, Nihon University School of Medicine, Tokyo 173-8610, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mariko","family":"Mizuno","sequence":"additional","affiliation":[{"name":"Department of Radiology, Nihon University School of Medicine, Tokyo 173-8610, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7104-0507","authenticated-orcid":false,"given":"Hayato","family":"Abe","sequence":"additional","affiliation":[{"name":"Department of Digestive Surgery, Nihon University School of Medicine, Tokyo 173-8610, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tokio","family":"Higaki","sequence":"additional","affiliation":[{"name":"Department of Digestive Surgery, Nihon University School of Medicine, Tokyo 173-8610, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3384-2709","authenticated-orcid":false,"given":"Yukiyasu","family":"Okamura","sequence":"additional","affiliation":[{"name":"Department of Digestive Surgery, Nihon University School of Medicine, Tokyo 173-8610, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tadatoshi","family":"Takayama","sequence":"additional","affiliation":[{"name":"Department of Digestive Surgery, Nihon University School of Medicine, Tokyo 173-8610, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2023,10,13]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/j.surg.2021.02.027","article-title":"Magnetic resonance elastography-based prediction of hepatocellular carcinoma recurrence after curative resection","volume":"170","author":"Abe","year":"2021","journal-title":"Surgery"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"3193","DOI":"10.1007\/s00261-021-02991-3","article-title":"Predictive value of combined computed tomography volumetry and magnetic resonance elastography for major complications after liver resection","volume":"46","author":"Shibutani","year":"2021","journal-title":"Abdom. 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