{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T19:56:59Z","timestamp":1787169419957,"version":"build-2736575974"},"reference-count":29,"publisher":"MDPI AG","issue":"22","license":[{"start":{"date-parts":[[2023,11,10]],"date-time":"2023-11-10T00:00:00Z","timestamp":1699574400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostics"],"abstract":"<jats:p>Purpose: to assess the tomographic retinal layers\u2019 thickness in eyes affected by branch retinal artery occlusion (BRAO) and to compare it to those of patients affected by primary open angle glaucoma (POAG). Methods: retrospective review of 27 patients; 16 with BRAO (16 eyes) and 11 with POAG (20 eyes) were identified among those who received SD-OCT scans, including analysis of macular retinal nerve fiber layer (mRNFL), ganglion cell layer (GCL), inner plexiform layer (IPL), inner nuclear layer (INL), neuroretinal rim (NRR), circumpapillary RNFL at 3.5 mm and hemisphere asymmetry (HA). Results: the total IPL and INL thinning difference between the two groups was statistically significant (p = 0.0067 and p &lt; 0.0001, respectively). The HA difference for the total macular thinning, mRNFL, GCL, IPL and INL (p &lt; 0.0001) was also statistically significant. The analysis of the average total retinal thinning, total mRNFL and GCL thinning showed no statistically significant difference between the two groups. Conclusions: unilateral inner retinal thinning may represent a sign of temporal BRAO, particularly for INL thinning and HA difference over 17\u00b5m in total retinal layer thinning. This information is particularly useful in the diagnosis of previous, undiagnosed BRAO and may help prevent further retinal arterial occlusion and possible cerebrovascular incidents.<\/jats:p>","DOI":"10.3390\/diagnostics13223428","type":"journal-article","created":{"date-parts":[[2023,11,13]],"date-time":"2023-11-13T02:30:29Z","timestamp":1699842629000},"page":"3428","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Inner Retinal Thinning Comparison between Branch Retinal Artery Occlusion and Primary Open-Angle Glaucoma"],"prefix":"10.3390","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1185-6942","authenticated-orcid":false,"given":"Gabriella","family":"De Salvo","sequence":"first","affiliation":[{"name":"Ophthalmology Department, University Hospital Southampton NHS Foundation Trust, Southampton SO16 6YD, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6290-0368","authenticated-orcid":false,"given":"Mohamed","family":"Oshallah","sequence":"additional","affiliation":[{"name":"Ophthalmology Department, University Hospital Southampton NHS Foundation Trust, Southampton SO16 6YD, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9034-635X","authenticated-orcid":false,"given":"Anastasios E.","family":"Sepetis","sequence":"additional","affiliation":[{"name":"Ophthalmology Department, University Hospital Southampton NHS Foundation Trust, Southampton SO16 6YD, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ramez","family":"Borbara","sequence":"additional","affiliation":[{"name":"Ophthalmology Department, University Hospital Southampton NHS Foundation Trust, Southampton SO16 6YD, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giovanni William","family":"Oliverio","sequence":"additional","affiliation":[{"name":"Biomedical, Dental and Morphological and Functional Images Sciences Department, University of Messina, 98122 Messina, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandro","family":"Meduri","sequence":"additional","affiliation":[{"name":"Biomedical, Dental and Morphological and Functional Images Sciences Department, University of Messina, 98122 Messina, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0247-2680","authenticated-orcid":false,"given":"Rino","family":"Frisina","sequence":"additional","affiliation":[{"name":"Ophthalmology Department, University of Padova, 35128 Padova, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7655-0469","authenticated-orcid":false,"given":"Aby","family":"Jacob","sequence":"additional","affiliation":[{"name":"Ophthalmology Department, University Hospital Southampton NHS Foundation Trust, Southampton SO16 6YD, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,11,10]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"2060","DOI":"10.1097\/IAE.0000000000000585","article-title":"Fundus changes in branch retinal arteriolar occlusion","volume":"35","author":"Hayreh","year":"2015","journal-title":"Retina"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1007\/s00347-016-0432-4","article-title":"Retinaler arterienverschluss","volume":"114","author":"Feltgen","year":"2017","journal-title":"Der Ophthalmol."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1097\/OPX.0000000000001170","article-title":"Differentiating occult branch retinal artery occlusion from primary open-angle glaucoma","volume":"95","author":"Amin","year":"2018","journal-title":"Optom. 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