{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T14:40:25Z","timestamp":1787496025114,"version":"build-2736575974"},"reference-count":30,"publisher":"MDPI AG","issue":"24","license":[{"start":{"date-parts":[[2023,12,14]],"date-time":"2023-12-14T00:00:00Z","timestamp":1702512000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostics"],"abstract":"<jats:p>Congenital high airway obstructive syndrome (CHAOS) is a rare congenital anomaly, frequently caused by laryngeal or tracheal atresia, tracheal stenosis, and obstructing laryngeal cysts. This is a congenital malformation, often fatal, with an unknown prevalence. Laryngeal atresia is the most frequent cause. We report a case of an intrauterine diagnosis of CHAOS and ascites in a 17-week fetus delivered at 38 weeks of gestation without other associated malformations. A fetoscopic procedure was performed at 22 weeks of gestation. An attempt was made to perforate the affected area to ensure pulmonary fluid circulation and the ascites\u2019 resolution. After birth, a tracheostomy was performed. The patient was mechanically ventilated until 11 months of age, when she was discharged with no cerebral or other complications of immediate postnatal anoxia or episodes of respiratory arrest. A laryngotracheoplasty was performed at 2 years old, but decannulation was not possible due to certain complications. At 5 years old, a new surgical intervention was performed, which allowed decannulation 6 months later.<\/jats:p>","DOI":"10.3390\/diagnostics13243658","type":"journal-article","created":{"date-parts":[[2023,12,14]],"date-time":"2023-12-14T03:58:02Z","timestamp":1702526282000},"page":"3658","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Congenital High Airway Obstructive Syndrome (CHAOS) Survival of a Newborn with Laryngeal Atresia"],"prefix":"10.3390","volume":"13","author":[{"given":"Carmen","family":"Heriseanu","sequence":"first","affiliation":[{"name":"Neonatal Intensive Care Unit, \u201cM.S. Curie\u201d Children\u2019s Hospital, Constantin Br\u00e2ncoveanu Boulevard, No. 20, 4th District, 041451 Bucharest, Romania"},{"name":"Faculty of Medicine, \u201cCarol Davila\u201d University of Medicine and Pharmacy, 020021 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mihaela","family":"Bizubac","sequence":"additional","affiliation":[{"name":"Neonatal Intensive Care Unit, \u201cM.S. Curie\u201d Children\u2019s Hospital, Constantin Br\u00e2ncoveanu Boulevard, No. 20, 4th District, 041451 Bucharest, Romania"},{"name":"Department of Neonatal Intensive Care, \u201cCarol Davila\u201d University of Medicine and Pharmacy, 020021 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Loredana","family":"Draghia","sequence":"additional","affiliation":[{"name":"Neonatal Intensive Care Unit, \u201cM.S. Curie\u201d Children\u2019s Hospital, Constantin Br\u00e2ncoveanu Boulevard, No. 20, 4th District, 041451 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Veronica","family":"Marcu","sequence":"additional","affiliation":[{"name":"Department of Radiology, \u201cM.S. Curie\u201d Children\u2019s Hospital, Constantin Br\u00e2ncoveanu Boulevard, No. 20, 4th District, 041451 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dan","family":"Gheorghe","sequence":"additional","affiliation":[{"name":"Department of ENT, \u201cCarol Davila\u201d University of Medicine and Pharmacy, 020021 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7778-0477","authenticated-orcid":false,"given":"Catalin","family":"Cirstoveanu","sequence":"additional","affiliation":[{"name":"Neonatal Intensive Care Unit, \u201cM.S. Curie\u201d Children\u2019s Hospital, Constantin Br\u00e2ncoveanu Boulevard, No. 20, 4th District, 041451 Bucharest, Romania"},{"name":"Department of Neonatal Intensive Care, \u201cCarol Davila\u201d University of Medicine and Pharmacy, 020021 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,12,14]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"115","DOI":"10.11152\/mu.2013.2066.171.haek","article-title":"Prenatal diagnosis of congenital high airway obstruction syndrome (CHAOS). Five case report","volume":"17","author":"Aslan","year":"2015","journal-title":"Med. Ultrason."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"1633","DOI":"10.1016\/j.jpedsurg.2010.01.022","article-title":"Predicting the severity of congenital high airway obstruction syndrome","volume":"45","author":"Roybal","year":"2010","journal-title":"J. Pediatr. 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