{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,13]],"date-time":"2026-01-13T02:34:39Z","timestamp":1768271679856,"version":"3.49.0"},"reference-count":11,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2024,1,4]],"date-time":"2024-01-04T00:00:00Z","timestamp":1704326400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Chosun University"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostics"],"abstract":"<jats:p>The frequency of concurrent thyroid cancer in patients with primary hyperparathyroidism (pHPT) varies. While the pathological association between thyroid and parathyroid disorders is frequently noted, the co-occurrence of parathyroid adenoma and papillary thyroid cancer is exceptionally rare. Furthermore, an ectopic parathyroid adenoma in the retropharyngeal space is exceedingly rare. Therefore, anatomical variations through the utilization of relevant diagnostic tools play a crucial role in guiding decisions pertaining to clinical manifestations, diagnostic methods, surgical interventions, and operative strategies for parathyroid tumors. We present a case of a 51-year-old female patient with papillary thyroid carcinoma in the right thyroid lobe and an ectopic parathyroid adenoma in the retropharyngeal space confirmed through surgical intervention. The elevated preoperative levels of serum calcium and parathyroid hormone, along with low serum phosphate, returned to normal ranges after surgery. This case sheds light on the unusual occurrence of an ectopic parathyroid adenoma in the retropharyngeal region within a thyroid cancer patient, providing valuable insights into the realm of thyroid malignancies.<\/jats:p>","DOI":"10.3390\/diagnostics14010110","type":"journal-article","created":{"date-parts":[[2024,1,4]],"date-time":"2024-01-04T04:05:38Z","timestamp":1704341138000},"page":"110","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["An Ectopic Parathyroid Adenoma of the Retropharynx in a Patient with Primary Hyperparathyroidism and Papillary Thyroid Cancer\u2014A Rare Case"],"prefix":"10.3390","volume":"14","author":[{"given":"Youngjae","family":"Lee","sequence":"first","affiliation":[{"name":"Department of Otorhinolaryngology-Head and Neck Surgery, Chosun University Hospital, Gwangju 61453, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wonyong","family":"Baek","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology-Head and Neck Surgery, Chosun University Hospital, Gwangju 61453, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiwoong","family":"Cho","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology-Head and Neck Surgery, Chosun University Hospital, Gwangju 61453, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3774-1406","authenticated-orcid":false,"given":"Jeonghyun","family":"Oh","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology-Head and Neck Surgery, Chosun University Hospital, Gwangju 61453, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2024,1,4]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"642","DOI":"10.1097\/01.sla.0000186337.83407.ec","article-title":"Primary hyperparathyroidism, cognition, and health-related quality of life","volume":"242","author":"Coker","year":"2005","journal-title":"Ann. Surg."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"e234421","DOI":"10.1136\/bcr-2020-234421","article-title":"Case report: Multiple concurrent atypical parathyroid adenomas: A rare occurrence","volume":"13","author":"Faulkner","year":"2020","journal-title":"BMJ Case Rep."},{"key":"ref_3","first-page":"i2","article-title":"The Pathophysiology of Secondary Hyperparathyroidism and the Consequences of Uncontrolled Mineral Metabolism in Chronic Kidney Disease: The Role of COSMOS","volume":"1","author":"Carrera","year":"2008","journal-title":"NDT Plus"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1308\/rcsann.2017.0112","article-title":"Current predictive models do not accurately differentiate between single and multi gland disease in primary hyperparathyroidism: A retrospective cohort study of two endocrine surgery units","volume":"100","author":"Edafe","year":"2018","journal-title":"Ann. R. Coll. Surg. 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Endocrinol."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"1611","DOI":"10.1002\/(SICI)1097-0142(19970415)79:8<1611::AID-CNCR26>3.0.CO;2-#","article-title":"Thyroid carcinoma found at parathyroidectomy: Association with primary, secondary, and tertiary hyperparathyroidism","volume":"79","author":"Burmeister","year":"1997","journal-title":"Cancer"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1016\/j.surg.2011.07.046","article-title":"Primary hyperparathyroidism with a history of head and neck irradiation: The consequences of associated thyroid tumors","volume":"150","author":"Wilson","year":"2011","journal-title":"Surgery"}],"container-title":["Diagnostics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2075-4418\/14\/1\/110\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T13:39:38Z","timestamp":1760103578000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2075-4418\/14\/1\/110"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,1,4]]},"references-count":11,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2024,1]]}},"alternative-id":["diagnostics14010110"],"URL":"https:\/\/doi.org\/10.3390\/diagnostics14010110","relation":{},"ISSN":["2075-4418"],"issn-type":[{"value":"2075-4418","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,1,4]]}}}