{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,31]],"date-time":"2026-10-31T00:34:29Z","timestamp":1793406869261,"version":"4.5.0"},"reference-count":184,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2024,1,5]],"date-time":"2024-01-05T00:00:00Z","timestamp":1704412800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Medical Research Council\/Fight for Sight Clinical Research Fellowship","award":["MR\/T001674\/1"],"award-info":[{"award-number":["MR\/T001674\/1"]}]},{"name":"Medical Research Council\/Fight for Sight Clinical Research Fellowship","award":["24CO4"],"award-info":[{"award-number":["24CO4"]}]},{"name":"Medical Research Council\/Fight for Sight Clinical Research Fellowship","award":["IILA-1117-20001"],"award-info":[{"award-number":["IILA-1117-20001"]}]},{"name":"Fight for Sight\/John Lee, Royal College of Ophthalmologists Primer Fellowship","award":["MR\/T001674\/1"],"award-info":[{"award-number":["MR\/T001674\/1"]}]},{"name":"Fight for Sight\/John Lee, Royal College of Ophthalmologists Primer Fellowship","award":["24CO4"],"award-info":[{"award-number":["24CO4"]}]},{"name":"Fight for Sight\/John Lee, Royal College of Ophthalmologists Primer Fellowship","award":["IILA-1117-20001"],"award-info":[{"award-number":["IILA-1117-20001"]}]},{"name":"National Institute for Health and Care Research (NIHR)","award":["MR\/T001674\/1"],"award-info":[{"award-number":["MR\/T001674\/1"]}]},{"name":"National Institute for Health and Care Research (NIHR)","award":["24CO4"],"award-info":[{"award-number":["24CO4"]}]},{"name":"National Institute for Health and Care Research (NIHR)","award":["IILA-1117-20001"],"award-info":[{"award-number":["IILA-1117-20001"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostics"],"abstract":"<jats:p>Since its introduction, optical coherence tomography (OCT) has revolutionized the field of ophthalmology and has now become an indispensable, noninvasive tool in daily practice. Most ophthalmologists are familiar with its use in the assessment and monitoring of retinal and optic nerve diseases. However, it also has important applications in the assessment of anterior segment structures, including the cornea, conjunctiva, sclera, anterior chamber, and iris, and has the potential to transform the clinical examination of these structures. In this review, we aim to provide a comprehensive overview of the potential clinical utility of anterior segment OCT (AS-OCT) for a wide range of anterior segment pathologies, such as conjunctival neoplasia, pterygium, scleritis, keratoconus, corneal dystrophies, and infectious\/noninfectious keratitis. In addition, the clinical applications of AS-OCT (including epithelial mapping) in preoperative planning and postoperative monitoring for corneal and refractive surgeries are discussed.<\/jats:p>","DOI":"10.3390\/diagnostics14020122","type":"journal-article","created":{"date-parts":[[2024,1,5]],"date-time":"2024-01-05T03:43:00Z","timestamp":1704426180000},"page":"122","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":39,"title":["Clinical Applications of Anterior Segment Optical Coherence Tomography: An Updated Review"],"prefix":"10.3390","volume":"14","author":[{"given":"Yu Jeat","family":"Chong","sequence":"first","affiliation":[{"name":"Birmingham and Midland Eye Centre, Birmingham B18 7QH, UK"},{"name":"Modality Ophthalmology, Modality Partnership, Birmingham B19 1BP, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8571-2503","authenticated-orcid":false,"given":"Matthew","family":"Azzopardi","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Royal Free Hospital, London NW3 2QG, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gulmeena","family":"Hussain","sequence":"additional","affiliation":[{"name":"University Hospitals Birmingham NHS Foundation Trust, Birmingham B15 2GW, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9708-2588","authenticated-orcid":false,"given":"Alberto","family":"Recchioni","sequence":"additional","affiliation":[{"name":"Birmingham and Midland Eye Centre, Birmingham B18 7QH, UK"},{"name":"Academic Unit of Ophthalmology, Institute of Inflammation and Ageing, University of Birmingham, Birmingham B15 2TT, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jaishree","family":"Gandhewar","sequence":"additional","affiliation":[{"name":"New Cross Hospital, Royal Wolverhampton NHS Trust, Wolverhampton WV10 0QP, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Constantinos","family":"Loizou","sequence":"additional","affiliation":[{"name":"Modality Ophthalmology, Modality Partnership, Birmingham B19 1BP, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ioannis","family":"Giachos","sequence":"additional","affiliation":[{"name":"Birmingham and Midland Eye Centre, Birmingham B18 7QH, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ankur","family":"Barua","sequence":"additional","affiliation":[{"name":"Birmingham and Midland Eye Centre, Birmingham B18 7QH, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1081-1141","authenticated-orcid":false,"given":"Darren S. J.","family":"Ting","sequence":"additional","affiliation":[{"name":"Birmingham and Midland Eye Centre, Birmingham B18 7QH, UK"},{"name":"Academic Unit of Ophthalmology, Institute of Inflammation and Ageing, University of Birmingham, Birmingham B15 2TT, UK"},{"name":"Academic Ophthalmology, School of Medicine, University of Nottingham, Nottingham NG7 2RD, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,1,5]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"2425","DOI":"10.1167\/iovs.10-6312","article-title":"Optical Coherence Tomography: History, Current Status, and Laboratory Work","volume":"52","author":"Gabriele","year":"2011","journal-title":"Investig. Ophthalmol. Vis. 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