{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,7]],"date-time":"2026-09-07T22:43:30Z","timestamp":1788821010794,"version":"build-2803163510"},"reference-count":6,"publisher":"MDPI AG","issue":"5","license":[{"start":{"date-parts":[[2024,2,29]],"date-time":"2024-02-29T00:00:00Z","timestamp":1709164800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostics"],"abstract":"<jats:p>Abdominal wall defects encompass three primary classifications: gastroschisis, omphalocele and anomalies resembling body stalk. Potential causative factors include early amnion rupture, amniotic bands, vascular disruptions or abnormal folding of the embryo. The prevalence of these defects stands at 1 in 14,000 live births. Body stalk anomaly is characterized by a substantial abdominal defect coupled with spine and limb anomalies, along with a very short or absent umbilical cord. We present a case of a rare abdominal defect known as body stalk anomaly, the most severe form of this spectrum of diseases. The diagnosis of this anomaly was established during the first trimester of pregnancy. Subsequently, the patient opted for pregnancy termination and chose not to undergo genetic testing. The anatomo-pathological results confirmed the findings. Body stalk anomaly is not compatible with life; therefore, early identification and understanding the clinical implications of this rare anomaly for informed decision-making in prenatal care are very important.<\/jats:p>","DOI":"10.3390\/diagnostics14050518","type":"journal-article","created":{"date-parts":[[2024,2,29]],"date-time":"2024-02-29T05:59:19Z","timestamp":1709186359000},"page":"518","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Body Stalk Anomaly"],"prefix":"10.3390","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8425-6307","authenticated-orcid":false,"given":"Nicolae","family":"Gic\u0103","sequence":"first","affiliation":[{"name":"Gynecology Department, Faculty of Medicine, Carol Davila University of Medicine and Pharmacy, 020021 Bucharest, Romania"},{"name":"Clinical Hospital of Obstetrics and Gynecology Filantropia, 011171 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Livia Mihaela","family":"Apostol","sequence":"additional","affiliation":[{"name":"Clinical Hospital of Obstetrics and Gynecology Filantropia, 011171 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Iulia","family":"Hulu\u021b\u0103","sequence":"additional","affiliation":[{"name":"Gynecology Department, Faculty of Medicine, Carol Davila University of Medicine and Pharmacy, 020021 Bucharest, Romania"},{"name":"Clinical Hospital of Obstetrics and Gynecology Filantropia, 011171 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9213-6735","authenticated-orcid":false,"given":"Anca Maria","family":"Panaitescu","sequence":"additional","affiliation":[{"name":"Gynecology Department, Faculty of Medicine, Carol Davila University of Medicine and Pharmacy, 020021 Bucharest, Romania"},{"name":"Clinical Hospital of Obstetrics and Gynecology Filantropia, 011171 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana Maria","family":"Vayna","sequence":"additional","affiliation":[{"name":"Gynecology Department, Faculty of Medicine, Carol Davila University of Medicine and Pharmacy, 020021 Bucharest, Romania"},{"name":"Clinical Hospital of Obstetrics and Gynecology Filantropia, 011171 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gheorghe","family":"Peltecu","sequence":"additional","affiliation":[{"name":"Gynecology Department, Faculty of Medicine, Carol Davila University of Medicine and Pharmacy, 020021 Bucharest, Romania"},{"name":"Clinical Hospital of Obstetrics and Gynecology Filantropia, 011171 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-8474-7598","authenticated-orcid":false,"given":"Nicoleta","family":"Gana","sequence":"additional","affiliation":[{"name":"Gynecology Department, Faculty of Medicine, Carol Davila University of Medicine and Pharmacy, 020021 Bucharest, Romania"},{"name":"Clinical Hospital of Obstetrics and Gynecology Filantropia, 011171 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,2,29]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"133","DOI":"10.15557\/JoU.2017.0020","article-title":"Body stalk anomaly: Antenatal sonographic diagnosis of this rare entity with review of literature","volume":"17","author":"Singh","year":"2017","journal-title":"J. Ultrason."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1046\/j.1469-0705.1997.10060416.x","article-title":"Body stalk anomaly at 10\u201314 weeks of gestation","volume":"10","author":"Daskalakis","year":"1997","journal-title":"Ultrasound Obstet. Gynecol."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"300060520980210","DOI":"10.1177\/0300060520980210","article-title":"First trimester diagnosis of body stalk anomaly complicated by ectopia cordis","volume":"48","author":"Yang","year":"2020","journal-title":"J. Int. Med. Res."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"3974139","DOI":"10.1155\/2016\/3974139","article-title":"Role of Ultrasound in Body Stalk Anomaly and Amniotic Band Syndrome","volume":"2016","author":"Routhu","year":"2016","journal-title":"Int. J. Reprod. Med."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"544","DOI":"10.1016\/S0022-3476(79)80759-3","article-title":"The amniotic disruption complex: Timing of amniotic rupture and variable spectra of consequent defects","volume":"95","author":"Higginbottom","year":"1979","journal-title":"J. Pediatr."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1159\/000444299","article-title":"Ultrasound Features and Management of Body Stalk Anomaly","volume":"40","author":"Panaitescu","year":"2016","journal-title":"Fetal Diagn. Ther."}],"container-title":["Diagnostics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2075-4418\/14\/5\/518\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T14:07:08Z","timestamp":1760105228000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2075-4418\/14\/5\/518"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,2,29]]},"references-count":6,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2024,3]]}},"alternative-id":["diagnostics14050518"],"URL":"https:\/\/doi.org\/10.3390\/diagnostics14050518","relation":{},"ISSN":["2075-4418"],"issn-type":[{"value":"2075-4418","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,2,29]]}}}