{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T11:41:03Z","timestamp":1784288463728,"version":"3.55.0"},"reference-count":117,"publisher":"MDPI AG","issue":"8","license":[{"start":{"date-parts":[[2024,4,12]],"date-time":"2024-04-12T00:00:00Z","timestamp":1712880000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostics"],"abstract":"<jats:p>Inflammatory bowel diseases (IBDs) affect over 4.9 million individuals worldwide. Colonoscopy (CS) is the gold-standard technique for diagnosis. The remissive\u2013recurrent pattern of evolution raises the need for non-invasive techniques to monitor disease activity. This review aims to present the advantages of intestinal ultrasound (IUS) in managing IBDs. Our search was conducted on the PubMed, Embase, and Cochrane (CENTRAL) databases, selecting original studies comparing IUS with other imaging and invasive monitoring methods. Our search yielded 8654 results, of which 107 met the inclusion criteria. Increased bowel wall thickness (BWT) and colour Doppler signal (CDS) are discriminative for disease activity. IUS can predict disease outcomes and detect response to treatment or postoperative recurrence. Contrast-enhanced ultrasound (CEUS) and elastography help differentiate fibrotic from inflammatory stenoses. The difficult rectal assessment limits the use of IUS in ulcerative colitis (UC). Transmural healing may develop as a therapeutic target as it is associated with better outcomes. Patients are compliant with this technique, and its results correlate well with CS and other imaging methods. In conclusion, IUS proves to be essential in assessing IBD activity and treatment response, predicting outcomes and detecting complications. CEUS and elastography are researched to improve the diagnostic values of IUS.<\/jats:p>","DOI":"10.3390\/diagnostics14080812","type":"journal-article","created":{"date-parts":[[2024,4,12]],"date-time":"2024-04-12T11:09:20Z","timestamp":1712920160000},"page":"812","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Novelties and Perspectives of Intestinal Ultrasound in the Personalised Management of Patients with Inflammatory Bowel Diseases\u2014A Systematic Review"],"prefix":"10.3390","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-6226-2196","authenticated-orcid":false,"given":"Vasile-Claudiu","family":"Mihai","sequence":"first","affiliation":[{"name":"Department of Radiology, University of Medicine and Pharmacy \u201cGrigore T. Popa\u201d, 700115 Iasi, Romania"},{"name":"Radiology Clinic, \u201cSt. Spiridon\u201d County Clinical Emergency Hospital, Bulevardul Independentei 1, 700111 Iasi, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liliana","family":"Gheorghe","sequence":"additional","affiliation":[{"name":"Department of Radiology, University of Medicine and Pharmacy \u201cGrigore T. Popa\u201d, 700115 Iasi, Romania"},{"name":"Radiology Clinic, \u201cSt. Spiridon\u201d County Clinical Emergency Hospital, Bulevardul Independentei 1, 700111 Iasi, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-9016-5690","authenticated-orcid":false,"given":"Ioana-Irina","family":"Rezu\u0219","sequence":"additional","affiliation":[{"name":"Department of Radiology, University of Medicine and Pharmacy \u201cGrigore T. Popa\u201d, 700115 Iasi, Romania"},{"name":"Radiology Clinic, \u201cSt. Spiridon\u201d County Clinical Emergency Hospital, Bulevardul Independentei 1, 700111 Iasi, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1694-3970","authenticated-orcid":false,"given":"Alina Ecaterina","family":"Jucan","sequence":"additional","affiliation":[{"name":"Discipline of Gastroenterology, Medical Department I, University of Medicine and Pharmacy \u201cGrigore T. Popa\u201d, 700115 Iasi, Romania"},{"name":"Institute of Gastroenterology and Hepatology, \u201cSt. Spiridon\u201d County Clinical Emergency Hospital, Bulevardul Independentei 1, 700111 Iasi, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mihaela-Cristiana","family":"Andronic","sequence":"additional","affiliation":[{"name":"Discipline of Gastroenterology, Medical Department I, University of Medicine and Pharmacy \u201cGrigore T. Popa\u201d, 700115 Iasi, Romania"},{"name":"Institute of Gastroenterology and Hepatology, \u201cSt. Spiridon\u201d County Clinical Emergency Hospital, Bulevardul Independentei 1, 700111 Iasi, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Otilia","family":"Gavrilescu","sequence":"additional","affiliation":[{"name":"Discipline of Gastroenterology, Medical Department I, University of Medicine and Pharmacy \u201cGrigore T. Popa\u201d, 700115 Iasi, Romania"},{"name":"Institute of Gastroenterology and Hepatology, \u201cSt. Spiridon\u201d County Clinical Emergency Hospital, Bulevardul Independentei 1, 700111 Iasi, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mihaela","family":"Dranga","sequence":"additional","affiliation":[{"name":"Discipline of Gastroenterology, Medical Department I, University of Medicine and Pharmacy \u201cGrigore T. Popa\u201d, 700115 Iasi, Romania"},{"name":"Institute of Gastroenterology and Hepatology, \u201cSt. Spiridon\u201d County Clinical Emergency Hospital, Bulevardul Independentei 1, 700111 Iasi, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrei-Mihai","family":"Andronic","sequence":"additional","affiliation":[{"name":"Discipline of Medical Semiology, Medical Department I, University of Medicine and Pharmacy \u201cGrigore T. Popa\u201d, 700115 Iasi, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cristina Cijevschi","family":"Prelipcean","sequence":"additional","affiliation":[{"name":"Institute of Gastroenterology and Hepatology, \u201cSt. Spiridon\u201d County Clinical Emergency Hospital, Bulevardul Independentei 1, 700111 Iasi, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ciprian","family":"Rezu\u0219","sequence":"additional","affiliation":[{"name":"Discipline of Internal Medicine, Medical Department I, University of Medicine and Pharmacy \u201cGrigore T. Popa\u201d, 700115 Iasi, Romania"},{"name":"3rd Internal Medicine Clinic, \u201cSf. Spiridon\u201d Emergency County Hospital, Bulevardul Independentei 1, 700111 Iasi, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C\u0103t\u0103lina","family":"Mihai","sequence":"additional","affiliation":[{"name":"Discipline of Gastroenterology, Medical Department I, University of Medicine and Pharmacy \u201cGrigore T. Popa\u201d, 700115 Iasi, Romania"},{"name":"Institute of Gastroenterology and Hepatology, \u201cSt. Spiridon\u201d County Clinical Emergency Hospital, Bulevardul Independentei 1, 700111 Iasi, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,4,12]]},"reference":[{"key":"ref_1","unstructured":"(2024, February 20). Ampersand. 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