{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T18:08:12Z","timestamp":1792001292831,"version":"4.4.0"},"reference-count":36,"publisher":"MDPI AG","issue":"11","license":[{"start":{"date-parts":[[2024,6,5]],"date-time":"2024-06-05T00:00:00Z","timestamp":1717545600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostics"],"abstract":"<jats:p>Introduction: The Enterococcus genus is a common cause of nosocomial infections, with vancomycin-resistant enterococci (VRE) posing a significant treatment challenge. Method: This retrospective study, spanning ten years (2012 to 2021), analyzes antimicrobial susceptibility patterns of Enterococcus species from clinical samples in a Saudi Arabian tertiary care hospital. Result: A total of 1034 Enterococcus isolates were collected, 729 from general wards and 305 from intensive care unit (ICU) patients. VRE accounted for 15.9% of isolates. E. faecalis was the most common species (54.3% of isolates and 2.7% of VRE), followed by E. faecium (33.6% of isolates and 41.2% of VRE). E. faecium exhibited the highest resistance to ciprofloxacin (84.1%), ampicillin (81.6%), and rifampicin (80%), with daptomycin (0.6%) and linezolid (3.1%) showing the lowest resistance. In E. faecalis, ciprofloxacin resistance was highest (59.7%), followed by rifampicin (20.1%) and ampicillin (11.8%). Daptomycin (0%), linezolid (1.5%), and vancomycin (2.7%) had the lowest resistance. VRE cases had higher mortality rates compared to vancomycin-sensitive enterococci (VSE). Conclusion: Eight different strains of Enterocci were identified. E. faecalis was the most commonly identified strain, while E. faecium had the highest percentage of VRE. VRE cases had a significantly higher mortality rate than VSE cases.<\/jats:p>","DOI":"10.3390\/diagnostics14111190","type":"journal-article","created":{"date-parts":[[2024,6,5]],"date-time":"2024-06-05T10:05:50Z","timestamp":1717581950000},"page":"1190","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Characterization and Antimicrobial Susceptibility Patterns of Enterococcus Species Isolated from Nosocomial Infections in a Saudi Tertiary Care Hospital over a Ten-Year Period (2012\u20132021)"],"prefix":"10.3390","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0974-7226","authenticated-orcid":false,"given":"Ali","family":"Al Bshabshe","sequence":"first","affiliation":[{"name":"Department of Medicine, College of Medicine, King Khalid University, Abha 61421, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1477-4379","authenticated-orcid":false,"given":"Abdullah","family":"Algarni","sequence":"additional","affiliation":[{"name":"Department of Family Medicine, Aseer Central Hospital, Abha 62523, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2489-4531","authenticated-orcid":false,"given":"Yahya","family":"Shabi","sequence":"additional","affiliation":[{"name":"Department of Microbiology and Clinical Parasitology, College of Medicine, King Khalid University, Abha 61421, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-9076-5684","authenticated-orcid":false,"given":"Abdulrahman","family":"Alwahhabi","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Aseer Central Hospital, Abha 62523, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammed","family":"Asiri","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Aseer Central Hospital, Abha 62523, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmed","family":"Alasmari","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Aseer Central Hospital, Abha 62523, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adil","family":"Alshehry","sequence":"additional","affiliation":[{"name":"Department of Medicine, College of Medicine, King Khalid University, Abha 61421, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5472-2311","authenticated-orcid":false,"given":"Wesam F.","family":"Mousa","sequence":"additional","affiliation":[{"name":"Department of Anesthesia and ICU, College of Medicine, Tanta University, Tanta 31512, Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nashwa","family":"Noreldin","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, College of Medicine, Tanta University, Tanta 31512, Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,6,5]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Ferede, Z.T., Tullu, K.D., Derese, S.G., and Yeshanew, A.G. 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