{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,12]],"date-time":"2026-08-12T11:09:03Z","timestamp":1786532943610,"version":"build-2736575974"},"reference-count":29,"publisher":"MDPI AG","issue":"12","license":[{"start":{"date-parts":[[2024,6,17]],"date-time":"2024-06-17T00:00:00Z","timestamp":1718582400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostics"],"abstract":"<jats:p>Objective: To report the symptom burden of anxiety and mood-related indicators following mTBI in collegiate student-athletes. Study Design: Retrospective cohort study of varsity collegiate athletes. Setting: University sports medicine at a tertiary care center. Patients: Division I college varsity athletes diagnosed with mTBI at a single institution between 2016 and 2019. Independent Variables: Pre- and post-injury. Main Outcome Measures: Comparisons between baseline testing and post-mTBI symptom scale assessments were made to determine changes in scores at the individual and group levels. The primary outcome was the prevalence of post-mTBI symptoms from within 72 h of injury through return to play. Associations with sport, sex, age, and return-to-play time were included. Results: Compared to baseline, mood and anxiety symptom scores were significantly higher acutely following mTBI (2.1 \u00b1 3.3 vs. 14.3 \u00b1 12.2; p &lt; 0.001). A family history of migraine was significantly associated with higher mood and anxiety symptom scores (20.0 \u00b1 14.9 with history vs. 13.3 \u00b1 11.3 without history; p = 0.042). Mood and anxiety symptom scores were highly correlated with non-mood and anxiety symptom scores for all athletes, including the subgroup with prolonged symptoms (r = 0.769; p &lt; 0.001). Conclusions: Symptoms of anxiety or mood disruption are common during the acute period post-injury in varsity college athletes. Risk factors for higher symptom reports immediately following mTBI and for prolonged symptoms (&gt;10 days) included female sex, those with a family history of migraine, and those with an overall higher symptom burden post-injury.<\/jats:p>","DOI":"10.3390\/diagnostics14121276","type":"journal-article","created":{"date-parts":[[2024,6,17]],"date-time":"2024-06-17T08:48:31Z","timestamp":1718614111000},"page":"1276","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Anxiety and Mood Disruption in Collegiate Athletes Acutely Following Mild Traumatic Brain Injury"],"prefix":"10.3390","volume":"14","author":[{"given":"Rachel","family":"Zhang","sequence":"first","affiliation":[{"name":"Department of Emergency Medicine, Stanford University, Stanford, CA 94304, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8346-2216","authenticated-orcid":false,"given":"Michael","family":"Martyna","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Stanford University, Stanford, CA 94304, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jordan","family":"Cornwell","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, Stanford University, Stanford, CA 94304, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masaru","family":"Teramoto","sequence":"additional","affiliation":[{"name":"Department of Physical Medicine & Rehabilitation, University of Utah, Salt Lake City, UT 84108, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mollie","family":"Selfridge","sequence":"additional","affiliation":[{"name":"Department of Sports Medicine, Stanford University, Stanford, CA 94304, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amanda","family":"Brown","sequence":"additional","affiliation":[{"name":"Department of Sports Medicine, Stanford University, Stanford, CA 94304, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jamshid","family":"Ghajar","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Brain Performance Center, Stanford University, Stanford, CA 94304, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angela","family":"Lumba-Brown","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, Stanford University, Stanford, CA 94304, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,6,17]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"8","DOI":"10.4172\/2472-1786.100046","article-title":"Quality of life perceptions in school-going adolescents with social anxiety","volume":"3","author":"Farooq","year":"2017","journal-title":"J. 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