{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,7]],"date-time":"2026-04-07T04:24:08Z","timestamp":1775535848327,"version":"3.50.1"},"reference-count":28,"publisher":"MDPI AG","issue":"19","license":[{"start":{"date-parts":[[2024,10,8]],"date-time":"2024-10-08T00:00:00Z","timestamp":1728345600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostics"],"abstract":"<jats:p>Malformative uropathy in children is one of the most common pathological conditions, with an incidence of 5\u201314% in newborns. Recent research shows that even in the current conditions, they are often diagnosed only in the advanced stages, when Chronic Kidney Disease is already affirming. This study\u2019s objective is to identify urinary tract anomalies, including malformative uropathies in the prenatal stage, using imaging techniques, namely ultrasound of the pregnant uterus. Using prenatal ultrasonography of the pregnant uterus and postnatal clinical and paraclinical examination, we prospectively evaluated a cohort of fifty children with pyelectasia. We describe the demographic and pathological characteristics of patients diagnosed with renal\u2013urinary abnormalities, as well as their postnatal management. A prenatal diagnosis made during the first 15 to 22 weeks of pregnancy enables the evaluation of early malformative uropathies and the determination of the best time to operate in order to minimize complications. When prenatal ultrasonography, fetal karyotype, tissue sample, and embryonic appendages work together, problems may be partially or entirely revealed by these methods due to mistakes made in imaging examinations. In the case of a pregnancy with an antenatal malformation detected, it is necessary for the delivery to take place in a clinic that can provide favorable services for the survival and investigation of the child born with malformative abnormalities.<\/jats:p>","DOI":"10.3390\/diagnostics14192243","type":"journal-article","created":{"date-parts":[[2024,10,8]],"date-time":"2024-10-08T12:02:10Z","timestamp":1728388930000},"page":"2243","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Prenatal Diagnosis of Reno-Urinary Malformations in a Tertiary Center of Republic of Moldavia"],"prefix":"10.3390","volume":"14","author":[{"given":"Victor","family":"Roller","sequence":"first","affiliation":[{"name":"Discipline of Pediatric Surgery, \u201cNicolae Testemi\u021banu\u201d State University of Medicine and Pharmacy, MD-2004 Chisinau, Moldova"},{"name":"Department of Obstetrics and Gynaecology, Public Health Institution, Institute \u201cMother and Child\u201d, MD-2004 Chisinau, Moldova"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Angela","family":"Ciuntu","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology, Public Health Institution, Institute \u201cMother and Child\u201d, MD-2004 Chisinau, Moldova"},{"name":"Departament of Pediatrics, \u201cNicolae Testemi\u021banu\u201d State University of Medicine and Pharmacy, MD-2004 Chisinau, Moldova"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3018-8011","authenticated-orcid":false,"given":"Elena","family":"\u021aarc\u0103","sequence":"additional","affiliation":[{"name":"Department Surgery II, Discipline of Pediatric Surgery and Orthopedics, \u201cGrigore T. Popa\u201d University of Medicine and Pharmacy, 700115 Ia\u0219i, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicolae Sebastian","family":"Ionescu","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery and Orthopedics, \u201cCarol Davila\u201d University of Medicine and Pharmacy, 020021 Bucharest, Romania"},{"name":"Romanian Academy of Medical Sciences, 030167 Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-6748-871X","authenticated-orcid":false,"given":"Teodora-Simina","family":"Dr\u0103goiu","sequence":"additional","affiliation":[{"name":"\u201cCarol Davila\u201d University of Medicine and Pharmacy, 020021 Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jana","family":"Bernic","sequence":"additional","affiliation":[{"name":"Discipline of Pediatric Surgery, \u201cNicolae Testemi\u021banu\u201d State University of Medicine and Pharmacy, MD-2004 Chisinau, Moldova"},{"name":"Department of Obstetrics and Gynaecology, Public Health Institution, Institute \u201cMother and Child\u201d, MD-2004 Chisinau, Moldova"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eva","family":"Gudumac","sequence":"additional","affiliation":[{"name":"Discipline of Pediatric Surgery, \u201cNicolae Testemi\u021banu\u201d State University of Medicine and Pharmacy, MD-2004 Chisinau, Moldova"},{"name":"Department of Obstetrics and Gynaecology, Public Health Institution, Institute \u201cMother and Child\u201d, MD-2004 Chisinau, Moldova"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emil","family":"Ceban","sequence":"additional","affiliation":[{"name":"Discipline of Pediatric Surgery, \u201cNicolae Testemi\u021banu\u201d State University of Medicine and Pharmacy, MD-2004 Chisinau, Moldova"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8317-422X","authenticated-orcid":false,"given":"Ana","family":"Mi\u0219ina","sequence":"additional","affiliation":[{"name":"Discipline of Pediatric Surgery, \u201cNicolae Testemi\u021banu\u201d State University of Medicine and Pharmacy, MD-2004 Chisinau, Moldova"},{"name":"Department of Obstetrics and Gynaecology, Public Health Institution, Institute \u201cMother and Child\u201d, MD-2004 Chisinau, Moldova"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tatiana","family":"B\u0103lu\u021bel","sequence":"additional","affiliation":[{"name":"Departament of Pediatrics, \u201cNicolae Testemi\u021banu\u201d State University of Medicine and Pharmacy, MD-2004 Chisinau, Moldova"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adriana","family":"Ignat","sequence":"additional","affiliation":[{"name":"Departament of Pediatrics, \u201cNicolae Testemi\u021banu\u201d State University of Medicine and Pharmacy, MD-2004 Chisinau, Moldova"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liliana","family":"Fuior-Bulhac","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology, Public Health Institution, Institute \u201cMother and Child\u201d, MD-2004 Chisinau, Moldova"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dana Elena","family":"M\u00eendru","sequence":"additional","affiliation":[{"name":"Departament of Pediatrics, \u201cGrigore T. Popa\u201d University of Medicine and Pharmacy, 700115 Ia\u0219i, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2024,10,8]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1159\/000049840","article-title":"Guidelines on urinary and Male Genital Tract infections European Associations og Urology","volume":"40","author":"Naber","year":"2013","journal-title":"Eur. Urol."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"261.e1","DOI":"10.1016\/j.jpurol.2016.04.024","article-title":"Urinary tract infections in childen with prenatal hydronephrosis: A risk assessement from the Society for Fetal Urology Hidronephrosis Registry","volume":"12","author":"Zee","year":"2016","journal-title":"J. Pediatr. Urol."},{"key":"ref_3","doi-asserted-by":"crossref","unstructured":"Chiodini, B., Ghassemi, M., Khelif, K., and Ismaili, K. (2019). 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