{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T01:30:52Z","timestamp":1760146252785,"version":"build-2065373602"},"reference-count":24,"publisher":"MDPI AG","issue":"21","license":[{"start":{"date-parts":[[2024,10,23]],"date-time":"2024-10-23T00:00:00Z","timestamp":1729641600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Moscow Center for Innovative Technologies in Healthcare"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostics"],"abstract":"<jats:p>Background: There is paucity of data in the available medical literature regarding the parameters of the volumetric perfusion of pancreas grafts. Methods: From 5 February 2016 to 23 December 2021, we performed perfusion computed tomography in 41 patients at different times after simultaneous pancreas and kidney transplantation. The study group consisted of 18 men (44%) and 23 women (56%) with a long history of type 1 diabetes mellitus complicated by terminal chronic renal failure. The results of the perfusion computed tomography of the pancreas graft were studied, and the effects of post-transplantation timing and graft revascularization peculiarities on volumetric perfusion parameters were evaluated. Results: The median arterial blood flow, arterial blood volume, and permeability of the pancreas graft were 115.1 [99.7;130.3] mL\/100 mL\/min, 46.7 [37.4;56.9] mL\/min, and 8.6 [4.1;11.4] mL\/100 mL\/min, respectively. No statistically significant differences in the averaged perfusion values were found in the head, body, and tail of the pancreas graft. The post-transplantation timing and the number of arteries involved in graft revascularization did not have a significant effect on the volumetric perfusion of the graft. Conclusion: The volumetric perfusion results of the pancreas graft correspond to those obtained in the study of pancreatic perfusion in healthy participants.<\/jats:p>","DOI":"10.3390\/diagnostics14212361","type":"journal-article","created":{"date-parts":[[2024,10,23]],"date-time":"2024-10-23T09:07:04Z","timestamp":1729674424000},"page":"2361","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Perfusion Computed Tomography for Assessing Pancreas Graft Volumetric Perfusion After Simultaneous Pancreas and Kidney Transplantation"],"prefix":"10.3390","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5731-3310","authenticated-orcid":false,"given":"Ilya V.","family":"Dmitriev","sequence":"first","affiliation":[{"name":"Sklifosovsky Research Institute for Emergency Medicine, 129090 Moscow, Russia"},{"name":"Department of Medical Cybernetics and Computer Science MBF, Pirogov Russian National Research Medical University, 117997 Moscow, Russia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5430-8524","authenticated-orcid":false,"given":"Rustam Sh.","family":"Muslimov","sequence":"additional","affiliation":[{"name":"Sklifosovsky Research Institute for Emergency Medicine, 129090 Moscow, Russia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3041-7478","authenticated-orcid":false,"given":"Yuriy A.","family":"Anisimov","sequence":"additional","affiliation":[{"name":"Sklifosovsky Research Institute for Emergency Medicine, 129090 Moscow, Russia"},{"name":"Radiological Department of Clinical Medical Center, FSBEI HE \u00abROSUNIMED\u00bb of MOH of Russia, 127473 Moscow, Russia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3292-8949","authenticated-orcid":false,"given":"Svetlana P.","family":"Shchelykalina","sequence":"additional","affiliation":[{"name":"Department of Medical Cybernetics and Computer Science MBF, Pirogov Russian National Research Medical University, 117997 Moscow, Russia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elena V.","family":"Grigorieva","sequence":"additional","affiliation":[{"name":"Radiological Department of Clinical Medical Center, FSBEI HE \u00abROSUNIMED\u00bb of MOH of Russia, 127473 Moscow, Russia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2167-8908","authenticated-orcid":false,"given":"Igor O.","family":"Shchekoturov","sequence":"additional","affiliation":[{"name":"Department of Radiology and Radiotherapy, I.M. Sechenov First Moscow State Medical University, 119991 Moscow, Russia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Natalya S.","family":"Serova","sequence":"additional","affiliation":[{"name":"Department of Radiology and Radiotherapy, I.M. Sechenov First Moscow State Medical University, 119991 Moscow, Russia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sergey K.","family":"Ternovoy","sequence":"additional","affiliation":[{"name":"Department of Radiology and Radiotherapy, I.M. Sechenov First Moscow State Medical University, 119991 Moscow, Russia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2024,10,23]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"568","DOI":"10.1007\/s11892-012-0293-4","article-title":"Transplantation of the pancreas","volume":"12","author":"Boggi","year":"2012","journal-title":"Curr. 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