{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T01:34:53Z","timestamp":1760146493282,"version":"build-2065373602"},"reference-count":12,"publisher":"MDPI AG","issue":"22","license":[{"start":{"date-parts":[[2024,11,12]],"date-time":"2024-11-12T00:00:00Z","timestamp":1731369600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Ministry of Health, Czech Republic\u2014Conceptual Development of Research Organization","award":["00064165"],"award-info":[{"award-number":["00064165"]}]},{"name":"General University Hospital in Prague","award":["00064165"],"award-info":[{"award-number":["00064165"]}]},{"name":"Research Area Surgical Disciplines, Abdominal Surgery","award":["00064165"],"award-info":[{"award-number":["00064165"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostics"],"abstract":"<jats:p>Mucocele of the appendix and pseudomyxoma peritonei are rare diseases. The clinical findings are nonspecific in the early stages of the disease. The sequelae of appendiceal mucocele, its perforation, and extensive peritoneal involvement via pseudomyxoma peritonei (jelly belly) are repeatedly described in the literature. We present the typical findings in the natural history of the disease.<\/jats:p>","DOI":"10.3390\/diagnostics14222532","type":"journal-article","created":{"date-parts":[[2024,11,12]],"date-time":"2024-11-12T12:49:56Z","timestamp":1731415796000},"page":"2532","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Natural History from Appendiceal Mucocele to Jelly Belly"],"prefix":"10.3390","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2948-8989","authenticated-orcid":false,"given":"David","family":"Hoskovec","sequence":"first","affiliation":[{"name":"1st Department of Surgery, General University Hospital Prague, 128 00 Prague, Czech Republic"},{"name":"1st Faculty of Medicine, Charles University, 120 00 Prague, Czech Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zden\u011bk","family":"Kr\u0161ka","sequence":"additional","affiliation":[{"name":"1st Department of Surgery, General University Hospital Prague, 128 00 Prague, Czech Republic"},{"name":"1st Faculty of Medicine, Charles University, 120 00 Prague, Czech Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adam","family":"Pudla\u010d","sequence":"additional","affiliation":[{"name":"1st Faculty of Medicine, Charles University, 120 00 Prague, Czech Republic"},{"name":"Departments of Radiodiagnostics, General University Hospital Prague, 128 00 Prague, Czech Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maty\u00e1\u0161","family":"Lochman","sequence":"additional","affiliation":[{"name":"1st Department of Surgery, General University Hospital Prague, 128 00 Prague, Czech Republic"},{"name":"1st Faculty of Medicine, Charles University, 120 00 Prague, Czech Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sabina","family":"Strohalmov\u00e1","sequence":"additional","affiliation":[{"name":"1st Department of Surgery, General University Hospital Prague, 128 00 Prague, Czech Republic"},{"name":"1st Faculty of Medicine, Charles University, 120 00 Prague, Czech Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrej","family":"Boc\u00e1n","sequence":"additional","affiliation":[{"name":"1st Faculty of Medicine, Charles University, 120 00 Prague, Czech Republic"},{"name":"Departments of Radiodiagnostics, General University Hospital Prague, 128 00 Prague, Czech Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pavel","family":"Ko\u017eelsk\u00fd","sequence":"additional","affiliation":[{"name":"1st Department of Surgery, General University Hospital Prague, 128 00 Prague, Czech Republic"},{"name":"1st Faculty of Medicine, Charles University, 120 00 Prague, Czech Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Petr","family":"Dytrych","sequence":"additional","affiliation":[{"name":"1st Department of Surgery, General University Hospital Prague, 128 00 Prague, Czech Republic"},{"name":"1st Faculty of Medicine, Charles University, 120 00 Prague, Czech Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2024,11,12]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1097\/COC.0000000000000911","article-title":"Comprehensive Understanding and Evolutional Therapeutic Schemes for Pseudomyxoma Peritonei: A Literature Review","volume":"45","author":"Ye","year":"2022","journal-title":"Am. J. Clin. Oncol."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1186\/s13023-021-01723-6","article-title":"Consensuses and Controversies on Pseudomyxoma Peritonei: A Review of the Published Consensus Statements and Guidelines","volume":"16","author":"Lin","year":"2021","journal-title":"Orphanet J. Rare Dis."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.ejso.2020.02.012","article-title":"Appendiceal Tumours and Pseudomyxoma Peritonei: Literature Review with PSOGI\/EURACAN Clinical Practice Guidelines for Diagnosis and Treatment","volume":"47","author":"Govaerts","year":"2021","journal-title":"Eur. J. Surg. Oncol."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1080\/02656736.2017.1310938","article-title":"Pseudomyxoma Peritonei: Natural History and Treatment","volume":"33","author":"Mittal","year":"2017","journal-title":"Int. J. Hyperth."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1186\/s13256-024-04612-1","article-title":"Pseudomyxoma Peritonei Leading to \u201cJelly Belly\u201d Abdomen: A Case Report and Review of the Literature","volume":"18","author":"Garg","year":"2024","journal-title":"J. Med. Case Rep."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"109","DOI":"10.4314\/gmj.v58i1.15","article-title":"Mucocoele of the Appendix","volume":"58","author":"Oyeh","year":"2024","journal-title":"Ghana Med. J."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"1237","DOI":"10.1111\/codi.14847","article-title":"What Is a \u2018Mucocele\u2019 of the Appendix and How Are These Lesions Best Managed? Beware the Wolf in Sheep\u2019s Clothing","volume":"21","author":"Sakata","year":"2019","journal-title":"Color. Dis."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"1414","DOI":"10.1046\/j.1365-2168.2000.01553.x","article-title":"Clinical Presentation of the Pseudomyxoma Peritonei Syndrome","volume":"87","author":"Esquivel","year":"2000","journal-title":"J. Br. Surg."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"355","DOI":"10.12659\/AJCR.890837","article-title":"Appendiceal Mucocele and Pseudomyxoma Peritonei; The Clinical Boundaries of a Subtle Disease","volume":"15","author":"Spyropoulos","year":"2014","journal-title":"Am. J. Case Rep."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"817","DOI":"10.1590\/S1807-59322010000800015","article-title":"Pseudomyxoma Peritonei Syndrome 12 Months after an Intact Resection of Malignant Mucocele of the Appendix: A Case Report","volume":"65","year":"2010","journal-title":"Clinics"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1007\/BF02523654","article-title":"Pleural Extension of Mucinous Tumor in Patients with Pseudomyxoma Peritonei Syndrome","volume":"7","author":"Pestieau","year":"2000","journal-title":"Ann. Surg. Oncol."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1590\/S0102-86502012000600009","article-title":"Levels of CEA and Ca 19-9 in the Sera and Peritoneal Cavity in Patients with Gastric and Pancreatic Cancers","volume":"27","author":"Hoskovec","year":"2012","journal-title":"Acta Cir. 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