{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T15:22:53Z","timestamp":1787498573151,"version":"build-2736575974"},"reference-count":36,"publisher":"MDPI AG","issue":"23","license":[{"start":{"date-parts":[[2024,11,30]],"date-time":"2024-11-30T00:00:00Z","timestamp":1732924800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100002301","name":"Estonian Research Council","doi-asserted-by":"publisher","award":["PRG1255"],"award-info":[{"award-number":["PRG1255"]}],"id":[{"id":"10.13039\/501100002301","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Swedish Gastroenterology and Hepatology Foundation","award":["PRG1255"],"award-info":[{"award-number":["PRG1255"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostics"],"abstract":"<jats:p>Background: There are no clinical or laboratory markers that can diagnose acute mesenteric ischemia (AMI) accurately. This study aimed to find differences in clinical and laboratory markers between arterial occlusive AMI and other acute abdominal diseases where AMI was initially suspected. Methods: This was a post hoc study of an international prospective multicenter study where data on patients with suspected AMI were collected. Independent factors associated with arterial occlusive AMI were evaluated in a multivariable logistic regression analysis. Results: The number of patients with arterial occlusive AMI was 231, consisting of thrombotic (n = 104), embolic (n = 61), and indeterminate (n = 66) occlusions. The non-AMI group included 287 patients, of whom 128 had strangulated bowel obstruction. Current smoking (odds ratio [OR] 2.56, 95% confidence interval [CI] 1.31\u20135.03), hypertension (OR 2.08, 95% CI 1.09\u20133.97), bowel emptying (OR 3.25, 95% CI 1.59\u20136.63), and leukocytosis (OR 1.54, 95% CI 1.14\u20132.08) at admission were independently associated with arterial occlusive AMI compared to the non-AMI group. Conclusions: This study found clinical and laboratory data to be associated with arterial occlusive AMI in patients with suspicion of AMI, which can possibly be of value in screening for arterial occlusive AMI at the emergency department. Further studies are needed to find more accurate diagnostic markers.<\/jats:p>","DOI":"10.3390\/diagnostics14232705","type":"journal-article","created":{"date-parts":[[2024,12,2]],"date-time":"2024-12-02T09:00:10Z","timestamp":1733130010000},"page":"2705","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Diagnostic Performance of Clinical and Routine Laboratory Data in Acute Mesenteric Arterial Occlusion\u2014An International Multicenter Study"],"prefix":"10.3390","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3076-500X","authenticated-orcid":false,"given":"Yasmin","family":"Soltanzadeh-Naderi","sequence":"first","affiliation":[{"name":"Department of Clinical Sciences, Malm\u00f6, Lund University, 214 28 Malm\u00f6, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1211-7372","authenticated-orcid":false,"given":"Annika","family":"Reintam Blaser","sequence":"additional","affiliation":[{"name":"Institute of Clinical Medicine, University of Tartu, 50090 Tartu, Estonia"},{"name":"Department of Intensive Care Medicine, Lucerne Cantonal Hospital, 6000 Lucerne, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Bj\u00f6rck","sequence":"additional","affiliation":[{"name":"Institute of Clinical Medicine, University of Tartu, 50090 Tartu, Estonia"},{"name":"Department of Surgical Sciences, Vascular Surgery, Uppsala University, 753 10 Uppsala, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8952-7620","authenticated-orcid":false,"given":"Alexandre","family":"Nuzzo","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, IBD and Intestinal Failure, Intestinal Stroke Center, AP-HP. Nord, Beaujon Hospital, Paris Cit\u00e9 University, 75006 Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joel","family":"Starkopf","sequence":"additional","affiliation":[{"name":"Institute of Clinical Medicine, University of Tartu, 50090 Tartu, Estonia"},{"name":"Tartu University Hospital, 50406 Tartu, Estonia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alastair","family":"Forbes","sequence":"additional","affiliation":[{"name":"Institute of Clinical Medicine, University of Tartu, 50090 Tartu, Estonia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5276-2555","authenticated-orcid":false,"given":"Marko","family":"Murruste","sequence":"additional","affiliation":[{"name":"Institute of Clinical Medicine, University of Tartu, 50090 Tartu, Estonia"},{"name":"Tartu University Hospital, 50406 Tartu, Estonia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6110-0417","authenticated-orcid":false,"given":"Kadri","family":"Tamme","sequence":"additional","affiliation":[{"name":"Institute of Clinical Medicine, University of Tartu, 50090 Tartu, Estonia"},{"name":"Tartu University Hospital, 50406 Tartu, Estonia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peep","family":"Talving","sequence":"additional","affiliation":[{"name":"Institute of Clinical Medicine, University of Tartu, 50090 Tartu, Estonia"},{"name":"Division of Acute Care Surgery, North Estonia Medical Centre, 13419 Tallinn, Estonia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna-Liisa","family":"Voomets","sequence":"additional","affiliation":[{"name":"Tartu University Hospital, 50406 Tartu, Estonia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4444-5979","authenticated-orcid":false,"given":"Merli","family":"Koitm\u00e4e","sequence":"additional","affiliation":[{"name":"Estonian Genome Center, Institute of Genomics, University of Tartu, 50090 Tartu, Estonia"},{"name":"Institute of Mathematics and Statistics, University of Tartu, 50090 Tartu, Estonia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1504-6162","authenticated-orcid":false,"given":"Miklosh","family":"Bala","sequence":"additional","affiliation":[{"name":"Hadassah Medical Center, Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem 9190500, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zsolt","family":"Bodnar","sequence":"additional","affiliation":[{"name":"Letterkenny University Hospital, Letterkenny F92 AE81, Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4823-0804","authenticated-orcid":false,"given":"Dumitru","family":"Casian","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Nicolae Testemitanu State University of Medicine and Pharmacy of the Republic of Moldova, MD-2004 Chisinau, Moldova"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zaza","family":"Demetrashvili","sequence":"additional","affiliation":[{"name":"N. 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