{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,29]],"date-time":"2026-06-29T16:39:49Z","timestamp":1782751189105,"version":"3.54.5"},"reference-count":32,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2024,12,25]],"date-time":"2024-12-25T00:00:00Z","timestamp":1735084800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"JSPS KAKENHI (Grants-in-Aid for Scientific Research)","award":["21K11633"],"award-info":[{"award-number":["21K11633"]}]},{"name":"JSPS KAKENHI (Grants-in-Aid for Scientific Research)","award":["16K09042"],"award-info":[{"award-number":["16K09042"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostics"],"abstract":"<jats:p>Objective: To determine the prevalence of frailty and examine its association with gastrointestinal-related quality of life (QOL) among older outpatients in a geriatric hospital. Methods: This cross-sectional study involved 1042 outpatients (age: \u226565 years) diagnosed using the revised Japanese version of the cardiovascular health study criteria. Data collection was performed by a multidisciplinary team. Results: Of the 1039 eligible subjects (male: n = 460 [44.3%]; mean age: 78.2 \u00b1 6.1 years), 172 (16.6%) had frailty (male: n = 77 [44.8%]; mean age: 80.9 \u00b1 6.2 years). The multivariate analysis revealed that age (odds ratio [OR]: 1.070, p &lt; 0.001), QOL (OR: 0.982, p = 0.009), a history of falls (OR: 1.702, p = 0.029), sarcopenia (OR: 4.708, p &lt; 0.001), steroid use (OR: 3.741, p = 0.001), analgesic drug use (OR: 2.056, p = 0.014), Mini Mental State Examination (OR: 0.915, p = 0.011), Geriatric Depression Scale 15 (OR: 1.101, p = 0.008), fullness-related QOL score (OR: 1.119, p = 0.010), chronic obstructive pulmonary disease assessment test (OR: 1.048, p = 0.007), and 10-item Eating Assessment Tool (OR: 1.071, p = 0.009) were related to frailty. Conclusions: The prevalence rate of frailty in older outpatients at a university hospital specializing in geriatric medicine was higher than that previously reported in community-dwelling individuals. Our study clarified that the fullness-related QOL score was related to frailty.<\/jats:p>","DOI":"10.3390\/diagnostics15010015","type":"journal-article","created":{"date-parts":[[2024,12,25]],"date-time":"2024-12-25T19:19:32Z","timestamp":1735154372000},"page":"15","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Association Between Gastrointestinal-Related Quality of Life and Frailty Using Baseline Data of the Prospective Cohort Study (JUSTICE-TOKYO Study)"],"prefix":"10.3390","volume":"15","author":[{"given":"Daisuke","family":"Asaoka","sequence":"first","affiliation":[{"name":"Department of Gastroenterology, Juntendo Tokyo Koto Geriatric Medical Center, Tokyo 136-0075, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Osamu","family":"Nomura","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Juntendo Tokyo Koto Geriatric Medical Center, Tokyo 136-0075, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3665-0537","authenticated-orcid":false,"given":"Koji","family":"Sugano","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine, Juntendo Tokyo Koto Geriatric Medical Center, Tokyo 136-0075, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-7536-0763","authenticated-orcid":false,"given":"Kei","family":"Matsuno","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine, Juntendo Tokyo Koto Geriatric Medical Center, Tokyo 136-0075, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-5053-2337","authenticated-orcid":false,"given":"Hiroyuki","family":"Inoshita","sequence":"additional","affiliation":[{"name":"Department of Nephrology, Juntendo Tokyo Koto Geriatric Medical Center, Tokyo 136-0075, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nobuto","family":"Shibata","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Juntendo Tokyo Koto Geriatric Medical Center, Tokyo 136-0075, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hideki","family":"Sugiyama","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Juntendo Tokyo Koto Geriatric Medical Center, Tokyo 136-0075, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noemi","family":"Endo","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Juntendo Tokyo Koto Geriatric Medical Center, Tokyo 136-0075, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshiyuki","family":"Iwase","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery, Juntendo Tokyo Koto Geriatric Medical Center, Tokyo 136-0075, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miyuki","family":"Tajima","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, Juntendo Tokyo Koto Geriatric Medical Center, Tokyo 136-0075, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naoko","family":"Sakuma","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, Juntendo Tokyo Koto Geriatric Medical Center, Tokyo 136-0075, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Megumi","family":"Inoue","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, Juntendo Tokyo Koto Geriatric Medical Center, Tokyo 136-0075, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariko","family":"Nagata","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, Juntendo Tokyo Koto Geriatric Medical Center, Tokyo 136-0075, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Taeko","family":"Mizutani","sequence":"additional","affiliation":[{"name":"Department of Nursing, Juntendo Tokyo Koto Geriatric Medical Center, Tokyo 136-0075, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mizuki","family":"Ishii","sequence":"additional","affiliation":[{"name":"Department of Nursing, Juntendo Tokyo Koto Geriatric Medical Center, Tokyo 136-0075, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sachi","family":"Iida","sequence":"additional","affiliation":[{"name":"Department of Nursing, Juntendo Tokyo Koto Geriatric Medical Center, Tokyo 136-0075, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshiko","family":"Miura","sequence":"additional","affiliation":[{"name":"Department of Nutrition, Juntendo Tokyo Koto Geriatric Medical Center, Tokyo 136-0075, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuji","family":"Nishizaki","sequence":"additional","affiliation":[{"name":"Medical Technology Innovation Center, Juntendo University, Tokyo 113-8421, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naotake","family":"Yanagisawa","sequence":"additional","affiliation":[{"name":"Medical Technology Innovation Center, Juntendo University, Tokyo 113-8421, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3648-5452","authenticated-orcid":false,"given":"Tsutomu","family":"Takeda","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Juntendo University School of Medicine, Tokyo 113-8421, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5979-4384","authenticated-orcid":false,"given":"Akihito","family":"Nagahara","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Juntendo University School of Medicine, Tokyo 113-8421, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katsumi","family":"Miyauchi","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Juntendo Tokyo Koto Geriatric Medical Center, Tokyo 136-0075, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,12,25]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1093\/gerona\/56.3.M146","article-title":"Cardiovascular Health Study Collaborative Research Group. 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