{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T00:38:47Z","timestamp":1759970327831,"version":"build-2065373602"},"reference-count":89,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2025,1,9]],"date-time":"2025-01-09T00:00:00Z","timestamp":1736380800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostics"],"abstract":"<jats:p>Background and Clinical Significance: Granulomatosis with polyangiitis (GPA) represents a rare autoimmune disease with granulomatous inflammation, tissue necrosis, and systemic vasculitis of the small and medium blood vessels. Although the clinical elements vary, aortic involvement is exceptional and it represents a challenge that requires a rapid intervention with the potential of displaying a fulminant evolution. Case Presentation: We report a 64-year-old male with an 18-year history of GPA who presented atypical low back pain. Following ultrasound and computed tomography exams, the initial suspicion was an intramural descending aorta hematoma, surrounded by a peri-aortic sleeve suggesting a chronic inflammation. Serial non-invasive assessments revealed a progressive lesion within the next 10 to 12 days to an aortic wall rupture, despite the absence of previous aneurysmal changes. The peri-aortic fibrous inflammatory sleeve was life-saving, and emergency minimally invasive surgery was successful, including the massive improvement in back pain. Conclusions: To our knowledge, this is a very rare scenario in GPA; we found only 18 other cases (the oldest report being from 1994). An interventional approach was mentioned in a few cases as seen in this instance. Glucocorticoid medication for GPA might act as a potential contributor to symptomatic osteoporotic fractures which require a prompt differential diagnosis. Unusual aortic manifestations (such as intramural aortic hematoma or aortic wall rupture) are difficult to recognize since the index of clinical suspicion is rather low. A prompt intervention may be life-saving and a multidisciplinary team is mandatory. Minimally invasive surgical correction of the aortic event represents an optimum management in the modern era. Such cases add to the limited data we have so far with respect to unusual outcomes in long-standing GPAs.<\/jats:p>","DOI":"10.3390\/diagnostics15020144","type":"journal-article","created":{"date-parts":[[2025,1,9]],"date-time":"2025-01-09T07:00:47Z","timestamp":1736406047000},"page":"144","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Minimally Invasive Surgical Approach in Granulomatosis with Polyangiitis Complicated with Intramural Descending Aorta Hematoma Followed by Aortic Wall Rupture"],"prefix":"10.3390","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-4402-7194","authenticated-orcid":false,"given":"Mihai-Lucian","family":"Ciobica","sequence":"first","affiliation":[{"name":"Department of Internal Medicine and Gastroenterology, \u201cCarol Davila\u201d University of Medicine and Pharmacy, 020021 Bucharest, Romania"},{"name":"Department of Internal Medicine I and Rheumatology, \u201cDr. Carol Davila\u201d Central Military University Emergency Hospital, 010825 Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexandru-Sebastian","family":"Botezatu","sequence":"additional","affiliation":[{"name":"Department of Angiography and Cardiac Catheterization, \u201cDr. Carol Davila\u201d Central Military Emergency University Hospital, 010825 Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zoltan","family":"Galajda","sequence":"additional","affiliation":[{"name":"Clinical Department of Cardiovascular Surgery, \u201cDr. Carol Davila\u201d Central Military Emergency University Hospital, 010825 Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8585-3835","authenticated-orcid":false,"given":"Mara","family":"Carsote","sequence":"additional","affiliation":[{"name":"Department of Endocrinology, \u201cCarol Davila\u201d University of Medicine and Pharmacy, 020021 Bucharest, Romania"},{"name":"Department of Clinical Endocrinology V, \u201cC.I. Parhon\u201d National Institute of Endocrinology, 011863 Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2274-5666","authenticated-orcid":false,"given":"Claudiu","family":"Nistor","sequence":"additional","affiliation":[{"name":"Department 4-Cardio-Thoracic Pathology, Thoracic Surgery II Discipline, \u201cCarol Davila\u201d University of Medicine and Pharmacy, 050474 Bucharest, Romania"},{"name":"Thoracic Surgery Department, \u201cDr. Carol Davila\u201d Central Military University Emergency Hospital, 010242 Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bianca-Andreea","family":"Sandulescu","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine and Gastroenterology, \u201cCarol Davila\u201d University of Medicine and Pharmacy, 020021 Bucharest, Romania"},{"name":"Department of Internal Medicine I and Rheumatology, \u201cDr. Carol Davila\u201d Central Military University Emergency Hospital, 010825 Bucharest, Romania"},{"name":"PhD Doctoral School, \u201cCarol Davila\u201d University of Medicine and Pharmacy, 020021 Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2025,1,9]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/j.ncl.2019.01.005","article-title":"Overview of the Vasculitides","volume":"37","author":"Younger","year":"2019","journal-title":"Neurol. Clin."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"e138","DOI":"10.1002\/oto2.138","article-title":"The Diagnosis of Granulomatosis with Polyangiitis When Serology and Biopsies are Negative","volume":"8","author":"Teames","year":"2024","journal-title":"OTO Open"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1016\/j.jaut.2014.01.028","article-title":"Diagnosis and classification of granulomatosis with polyangiitis (aka Wegener\u2019s granulomatosis)","volume":"48\u201349","author":"Lutalo","year":"2014","journal-title":"J. Autoimmun."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1053\/j.ajkd.2019.04.031","article-title":"ANCA-Associated Vasculitis: Core Curriculum 2020","volume":"75","author":"Geetha","year":"2020","journal-title":"Am. J. Kidney Dis."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"2067","DOI":"10.1002\/art.40577","article-title":"Epidemiology and Outcomes of Granulomatosis with Polyangiitis in Pediatric and Working-Age Adult Populations In the United States: Analysis of a Large National Claims Database","volume":"70","author":"Panupattanapong","year":"2018","journal-title":"Arthritis Rheumatol."},{"key":"ref_6","first-page":"2060","article-title":"Increasing incidence of Wegener\u2019s granulomatosis in Sweden, 1975\u20132001","volume":"33","author":"Knight","year":"2006","journal-title":"J Rheumatol."},{"key":"ref_7","first-page":"S81","article-title":"Incidence of Wegener\u2019s granulomatosis in Finland 1981\u20132000","volume":"26","author":"Takala","year":"2008","journal-title":"Clin Exp Rheumatol."},{"key":"ref_8","first-page":"445","article-title":"Granulomatosis with polyangiitis according to geographic origin and ethnicity: Clinical-biological presentation and outcome in a French population","volume":"56","author":"Terrier","year":"2017","journal-title":"Rheumatology"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"1412","DOI":"10.1002\/art.24544","article-title":"Prevalence and incidence of Wegener\u2019s granulomatosis in the UK general practice research database","volume":"61","author":"Watts","year":"2009","journal-title":"Arthritis Rheum."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"1916","DOI":"10.1093\/rheumatology\/ker205","article-title":"Comparison of the epidemiology of anti-neutrophil cytoplasmic antibody-associated vasculitis between Japan and the U.K","volume":"50","author":"Fujimoto","year":"2011","journal-title":"Rheumatology"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"e23","DOI":"10.1111\/j.1445-5994.2011.02700.x","article-title":"Wegener\u2019s granulomatosis: Treatment and survival characteristics in a high-prevalence southern hemisphere region","volume":"42","author":"Khan","year":"2012","journal-title":"Intern. Med. J."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"926","DOI":"10.1093\/rheumatology\/ker454","article-title":"The contrasting epidemiology of granulomatosis with polyangiitis (Wegener\u2019s) and microscopic polyangiitis","volume":"51","author":"Watts","year":"2012","journal-title":"Rheumatology"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"1016","DOI":"10.2215\/CJN.01461005","article-title":"Incidence of ANCA-associated primary renal vasculitis in the Miyazaki Prefecture: The first population-based, retrospective, epidemiologic survey in Japan","volume":"1","author":"Fujimoto","year":"2006","journal-title":"Clin. J. Am. Soc. Nephrol."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"776","DOI":"10.1111\/j.1445-5994.2008.01694.x","article-title":"Wegener\u2019s granulomatosis: Epidemiological and clinical features in a South Australian study","volume":"38","author":"Hissaria","year":"2008","journal-title":"Intern. Med. J."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1016\/j.rdc.2010.04.002","article-title":"Epidemiology of ANCA-associated vasculitis","volume":"36","author":"Ntatsaki","year":"2010","journal-title":"Rheum. Dis. Clin. North Am."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"1560","DOI":"10.1093\/rheumatology\/kep304","article-title":"Incidence and survival rates in Wegener\u2019s granulomatosis, microscopic polyangiitis, Churg-Strauss syndrome and polyarteritis nodosa","volume":"48","author":"Mohammad","year":"2009","journal-title":"Rheumatology"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"1779","DOI":"10.1007\/s00296-017-3818-y","article-title":"Anti-neutrophil cytoplasmic antibody-associated vasculitis: Prevalence, treatment, and outcomes","volume":"37","author":"Shi","year":"2017","journal-title":"Rheumatol. Int."},{"key":"ref_18","first-page":"78","article-title":"Gender-Dependent Associations Between Digit Ratio and Genetic Polymorphisms, BMI, and Reproductive Factors","volume":"118","author":"Nica","year":"2025","journal-title":"Rom. J. Mil. Med."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"e17231","DOI":"10.2196\/17231","article-title":"Clinical Characteristics of an Internet-Based Cohort of Patient-Reported Diagnosis of Granulomatosis with Polyangiitis and Microscopic Polyangiitis: Observational Study","volume":"22","author":"Springer","year":"2020","journal-title":"J. Med. Internet Res."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1111\/1756-185X.13398","article-title":"Is granulomatosis with polyangiitis in Asia different from the West?","volume":"22","author":"Naidu","year":"2019","journal-title":"Int. J. Rheum. Dis."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"31","DOI":"10.5582\/irdr.2015.01015","article-title":"Using inpatient data to estimate the prevalence of Wegener\u2019s granulomatosis in China","volume":"5","author":"Liu","year":"2016","journal-title":"Intractable Rare Dis. Res."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"435","DOI":"10.46497\/ArchRheumatol.2021.8594","article-title":"Predictive factors of mortality in granulomatosis with polyangiitis: A single-center study","volume":"36","year":"2021","journal-title":"Arch. Rheumatol."},{"key":"ref_23","first-page":"S435","article-title":"Bone mineral density and vitamin D levels in patients with rheumatoid arthritis","volume":"28","author":"Anghel","year":"2017","journal-title":"Osteoporos. Int."},{"key":"ref_24","first-page":"e9690","article-title":"Aortic Involvement in Antineutrophil Cytoplasmic Antibodies Vasculitis, a Coincidence or a Real Association?","volume":"12","author":"Tariq","year":"2020","journal-title":"Cureus"},{"key":"ref_25","first-page":"47","article-title":"The Link Between Bone Osteocalcin and Energy Metabolism in a Group of Postmenopausal Women","volume":"45","author":"Dumitru","year":"2019","journal-title":"Curr. Health Sci. J."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1136\/annrheumdis-2021-221795","article-title":"2022 American College of Rheumatology\/European Alliance of Associations for Rheumatology classification criteria for granulomatosis with polyangiitis","volume":"81","author":"Robson","year":"2022","journal-title":"Ann. Rheum Dis."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1136\/annrheumdis-2021-221794","article-title":"2022 American College of Rheumatology\/European Alliance of Associations for Rheumatology Classification Criteria for Eosinophilic Granulomatosis with Polyangiitis","volume":"81","author":"Grayson","year":"2022","journal-title":"Ann. Rheum Dis."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1002\/art.41983","article-title":"2022 American College of Rheumatology\/European Alliance of Associations for Rheumatology Classification Criteria for Microscopic Polyangiitis","volume":"74","author":"Suppiah","year":"2022","journal-title":"Arthritis Rheumatol."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"153","DOI":"10.5152\/eujrheum.2022.20248","article-title":"Updates in ANCA-associated vasculitis","volume":"9","author":"Ross","year":"2022","journal-title":"Eur. J. Rheumatol."},{"key":"ref_30","doi-asserted-by":"crossref","unstructured":"Konstantouli, A.M., Lioulios, G., Stai, S., Moysidou, E., Fylaktou, A., Papagianni, A., and Stangou, M. (2022). Type of ANCA May Be Indispensable in Distinguishing Subphenotypes of Different Clinical Entities in ANCA-Associated Vasculitis. Life, 12.","DOI":"10.20944\/preprints202208.0316.v1"},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"2567","DOI":"10.2147\/JIR.S284768","article-title":"ANCA Associated Vasculitis Subtypes: Recent Insights and Future Perspectives","volume":"15","author":"Austin","year":"2022","journal-title":"J. Inflamm. Res."},{"key":"ref_32","first-page":"1321","article-title":"The role of tobacco smoking in anti-neutrophil cytoplasmic antibody-associated vasculitis: A systematic review","volume":"42","author":"Moretti","year":"2024","journal-title":"Clin. Exp. Rheumatol."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"355","DOI":"10.3892\/etm.2023.12054","article-title":"Therapeutic management of atypical antipsychotic-related metabolic dysfunctions using GLP-1 receptor agonists: A systematic review","volume":"26","author":"Vasiliu","year":"2023","journal-title":"Exper Ther. Med."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"e70010","DOI":"10.1002\/iid3.70010","article-title":"COVID-19-induced granulomatosis with polyangiitis: A case report of a 16-year-old East Asian and literature review","volume":"12","author":"Jiang","year":"2024","journal-title":"Immun. Inflamm. Dis."},{"key":"ref_35","first-page":"e50088","article-title":"An Unusual Presentation of Granulomatosis with Polyangiitis (Wegener\u2019s) After SARS-CoV-2 Infection","volume":"15","author":"Romanello","year":"2023","journal-title":"Cureus"},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"rkad021","DOI":"10.1093\/rap\/rkad021","article-title":"Vitamin D status in ANCA-associated vasculitis","volume":"7","author":"Doubelt","year":"2023","journal-title":"Rheumatol. Adv. Pract."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"723","DOI":"10.6061\/clinics\/2017(12)02","article-title":"Serum 25-hydroxyvitamin D levels in patients with Granulomatosis with Polyangiitis: Association with respiratory infection","volume":"72","author":"Perez","year":"2017","journal-title":"Clinics"},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"146","DOI":"10.5114\/reum.2021.107430","article-title":"Vitamin D supply in patients with rheumatic diseases in Poland\u2014A pilot study","volume":"59","author":"Runowska","year":"2021","journal-title":"Reumatologia"},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"125","DOI":"10.3892\/etm.2023.11824","article-title":"Impact of SGLT2 inhibitors on metabolic status in patients with psychiatric disorders undergoing treatment with second-generation antipsychotics (Review)","volume":"25","author":"Vasiliu","year":"2023","journal-title":"Exp. Ther. Med."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"23","DOI":"10.7861\/clinmed.23-6-s23","article-title":"Cocaine-induced granulomatosis with polyangiitis: An under-recognised condition","volume":"23","author":"Charn","year":"2023","journal-title":"Clin. Med."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"rkad027","DOI":"10.1093\/rap\/rkad027","article-title":"Cocaine-induced granulomatosis with polyangiitis-an under-recognized condition","volume":"7","author":"Gill","year":"2023","journal-title":"Rheumatol. Adv. Pract."},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1111\/nep.13747","article-title":"Systemic complement activation in anti-neutrophil cytoplasmic antibody-associated vasculitis and necrotizing glomerulonephritis","volume":"26","author":"Bantis","year":"2021","journal-title":"Nephrology"},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"1114","DOI":"10.1002\/art.40471","article-title":"Brief Report: Circulating Cytokine Profiles and Antineutrophil Cytoplasmic Antibody Specificity in Patients with Antineutrophil Cytoplasmic Antibody-Associated Vasculitis","volume":"70","author":"Berti","year":"2018","journal-title":"Arthritis Rheumatol."},{"key":"ref_44","doi-asserted-by":"crossref","unstructured":"Potentas-Policewicz, M., and Fijolek, J. (2024). Granulomatosis with polyangiitis: Clinical characteristics and updates in diagnosis. Front. Med., 11.","DOI":"10.3389\/fmed.2024.1369233"},{"key":"ref_45","first-page":"6","article-title":"ANCA-Associated Vasculitis: Practical Issues in Management","volume":"34","author":"Roper","year":"2024","journal-title":"Indian J. Nephrol."},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"42","DOI":"10.7861\/clinmed.22-4-s42","article-title":"A rare case report of granulomatosis with polyangiitis presenting with thrombus of the ascending aorta","volume":"22","author":"Tzanninis","year":"2022","journal-title":"Clin. Med."},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"e24","DOI":"10.1097\/RHU.0000000000001213","article-title":"Periaortic Mass Simulating Aortic Graft Infection as a Rare Presentation of Granulomatosis with Polyangiitis","volume":"27","author":"Carrascosa","year":"2021","journal-title":"J. Clin. Rheumatol."},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"e231","DOI":"10.7861\/clinmed.2020-1037","article-title":"Lessons of the month: ANCA-associated vasculitis-granulomatosis with polyangiitis: \u2019the great mimic\u2019","volume":"21","author":"Hesford","year":"2021","journal-title":"Clin. Med."},{"key":"ref_49","first-page":"144","article-title":"Successful use of rituximab in granulomatosis with polyangiitis with aortic inflammation","volume":"37","author":"Bitencourt","year":"2019","journal-title":"Clin. Exp. Rheumatol."},{"key":"ref_50","doi-asserted-by":"crossref","unstructured":"Pan, L., Yan, J.H., Gao, F.Q., Li, H., Han, S.S., Cao, G.H., Lv, C.J., and Wang, X.Z. (2019). Case report of a 28-year-old man with aortic dissection and pulmonary shadow due to granulomatosis with polyangiitis. BMC Pulm. Med., 19.","DOI":"10.1186\/s12890-019-0884-9"},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"e226795","DOI":"10.1136\/bcr-2018-226795","article-title":"Aortitis and pachymeningitis: An unusual combination in granulomatosis with polyangiitis (myeloperoxidase-associated vasculitis)","volume":"12","author":"Parperis","year":"2019","journal-title":"BMJ Case Rep."},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"e11","DOI":"10.1016\/j.athoracsur.2018.02.015","article-title":"Granulomatosis with Polyangiitis Involving the Ascending Aorta","volume":"106","author":"Kim","year":"2018","journal-title":"Ann. Thorac. Surg."},{"key":"ref_53","first-page":"121","article-title":"Retroperitoneal fibrosis with periaortitis: A case report of an unusual form of presentation of granulomatosis with polyangiitis","volume":"19","author":"Fernandez","year":"2016","journal-title":"Respir. Med. Case Rep."},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"699","DOI":"10.3109\/14397595.2015.1021950","article-title":"Large-vessel involvement in granulomatosis with polyangiitis successfully treated with rituximab: A case report and literature review","volume":"27","author":"Ozaki","year":"2017","journal-title":"Mod. Rheumatol."},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1186\/1752-1947-7-202","article-title":"Aortic aneurysm rupture as a rare complication of granulomatosis with polyangiitis: A case report","volume":"7","author":"Ohta","year":"2013","journal-title":"J. Med. Case Rep."},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1093\/ndtplus\/sfr116","article-title":"cANCA-associated aortitis","volume":"5","author":"Amos","year":"2012","journal-title":"Clin. Kidney J."},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1097\/RHU.0b013e31823abf2f","article-title":"Granulomatosis with polyangiitis (Wegener\u2019s) presenting as a periaortic mass","volume":"17","author":"Shmagel","year":"2011","journal-title":"J. Clin. Rheumatol."},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"1485","DOI":"10.1016\/j.jvs.2011.05.014","article-title":"Aortitis with aneurysm formation as a rare complication of Wegener\u2019s granulomatosis","volume":"54","author":"Willems","year":"2011","journal-title":"J. Vasc. Surg."},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"e15","DOI":"10.1016\/j.avsg.2009.06.011","article-title":"Aortic aneurysm and orchitis due to Wegener\u2019s granulomatosis","volume":"23","author":"Minnee","year":"2009","journal-title":"Ann. Vasc. Surg."},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1007\/s10067-004-0998-0","article-title":"p-ANCA-associated periaortitis with histological proof of Wegener\u2019s granulomatosis: Case report","volume":"24","author":"Carels","year":"2005","journal-title":"Clin. Rheumatol."},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1053\/hupa.2002.124331","article-title":"Atypical manifestation of a cytoplasmic antineutrophil cytoplasmic antibody (PR3-ANCA)-associated vasculitis with involvement of aortic intima and parietal endocardium","volume":"33","author":"Schildhaus","year":"2002","journal-title":"Hum. Pathol."},{"key":"ref_62","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1007\/s100670050038","article-title":"Periaortitis and aortic dissection due to Wegener\u2019s granulomatosis","volume":"19","author":"Blockmans","year":"2000","journal-title":"Clin. Rheumatol."},{"key":"ref_63","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1016\/S0009-9260(05)82876-4","article-title":"Indium-111 labelled leucocyte uptake in aortitis","volume":"49","author":"Fink","year":"1994","journal-title":"Clin. Radiol."},{"key":"ref_64","doi-asserted-by":"crossref","unstructured":"Nistor, C.E., G\u0103van, C.S., Ciritel, A.A., Nemes, A.F., and Ciuche, A. (2022). The Association of Minimally Invasive Surgical Approaches and Mortality in Patients with Malignant Pleuropericarditis\u2014A 10 Year Retrospective Observational Study. Medicina, 58.","DOI":"10.3390\/medicina58060718"},{"key":"ref_65","first-page":"476","article-title":"Metastases in daily endocrine practice","volume":"51","author":"Carsote","year":"2016","journal-title":"Arch. Balk. Med. Union"},{"key":"ref_66","doi-asserted-by":"crossref","unstructured":"Mitric\u0103, M., Lorusso, L., Badea, A.A., S\u00eerbu, C.A., Ple\u0219a, A., St\u0103nescu, A.A., Ple\u0219a, F.C., S\u00eerbu, O.M., and Munteanu, A.E. (2024). The Hidden Heart: Exploring Cardiac Damage Post-Stroke: A Narrative Review. Medicina, 60.","DOI":"10.3390\/medicina60101699"},{"key":"ref_67","doi-asserted-by":"crossref","first-page":"1863","DOI":"10.2147\/CIA.S265103","article-title":"Severe Aortic Stenosis and ATTRwt Amyloidosis - Beware in the Aging: A Case Report and Review of the Literature","volume":"15","author":"Adam","year":"2020","journal-title":"Clin. Interv. Aging"},{"key":"ref_68","first-page":"800","article-title":"News on the imaging of large vessel vasculitis","volume":"83","author":"Petzinna","year":"2024","journal-title":"Z. Rheumatol."},{"key":"ref_69","first-page":"25","article-title":"Contrast-enhanced ultrasound-clinical applications","volume":"114","author":"Anghel","year":"2011","journal-title":"Rom. J. Mil. Med."},{"key":"ref_70","first-page":"9","article-title":"The role of contrast-enhanced ultrasound in risk assessment of carotid atheroma","volume":"119","author":"Stanciu","year":"2016","journal-title":"Rom. J. Mil. Med."},{"key":"ref_71","doi-asserted-by":"crossref","first-page":"e003379","DOI":"10.1136\/rmdopen-2023-003379","article-title":"Imaging in diagnosis, monitoring and outcome prediction of large vessel vasculitis: A systematic literature review and meta-analysis informing the 2023 update of the EULAR recommendations","volume":"9","author":"Bosch","year":"2023","journal-title":"RMD Open"},{"key":"ref_72","doi-asserted-by":"crossref","unstructured":"Carubbi, F., Bosch, P., Machado, P.M., Scir\u00e8, C.A., Alunno, A., Proft, F., Baraliakos, X., and Dejaco, C. (2021). Current Practice of Imaging-Guided Interventional Procedures in Rheumatic and Musculoskeletal Diseases: Results of a Multinational Multidisciplinary Survey. Front. Med., 8.","DOI":"10.3389\/fmed.2021.779975"},{"key":"ref_73","doi-asserted-by":"crossref","first-page":"e001864","DOI":"10.1136\/rmdopen-2021-001864","article-title":"Value of imaging to guide interventional procedures in rheumatic and musculoskeletal diseases: A systematic literature review informing EULAR points to consider","volume":"7","author":"Bosch","year":"2021","journal-title":"RMD Open"},{"key":"ref_74","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.avsg.2024.06.028","article-title":"Outcomes of Thoracic and Complex Endovascular Aortic Repair in Patients with Renal Insufficiency","volume":"109","author":"Elsayed","year":"2024","journal-title":"Ann. Vasc. Surg."},{"key":"ref_75","doi-asserted-by":"crossref","first-page":"e22157","DOI":"10.1097\/MD.0000000000022157","article-title":"Late outcomes of endovascular aortic stent graft therapy in patients with chronic kidney disease","volume":"99","author":"Wu","year":"2020","journal-title":"Medicine"},{"key":"ref_76","doi-asserted-by":"crossref","first-page":"e2432041","DOI":"10.1001\/jamanetworkopen.2024.32041","article-title":"Conservative Treatments in the Management of Acute Painful Vertebral Compression Fractures: A Systematic Review and Network Meta-Analysis","volume":"7","author":"Alimy","year":"2024","journal-title":"JAMA Netw. Open"},{"key":"ref_77","first-page":"587","article-title":"Osteoporotic vertebral fractures: Natural history and impact","volume":"68","year":"2024","journal-title":"Rev. Esp. Cir. Ortop. Traumatol."},{"key":"ref_78","doi-asserted-by":"crossref","unstructured":"Al Taha, K., Lauper, N., Bauer, D.E., Tsoupras, A., Tessitore, E., Biver, E., and Dominguez, D.E. (2024). Multidisciplinary and Coordinated Management of Osteoporotic Vertebral Compression Fractures: Current State of the Art. J. Clin. Med., 13.","DOI":"10.3390\/jcm13040930"},{"key":"ref_79","doi-asserted-by":"crossref","first-page":"934","DOI":"10.31616\/asj.2022.0441","article-title":"Management of Osteoporotic Vertebral Fracture: Review Update 2022","volume":"16","author":"Jang","year":"2022","journal-title":"Asian Spine J."},{"key":"ref_80","doi-asserted-by":"crossref","first-page":"898","DOI":"10.31616\/asj.2020.0594","article-title":"Current Concepts in the Management of Osteoporotic Vertebral Fractures: A Narrative Review","volume":"14","author":"Jang","year":"2020","journal-title":"Asian Spine J."},{"key":"ref_81","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1007\/s00393-022-01255-9","article-title":"Osteoporotic vertebral fractures-From diagnosis to treatment","volume":"82","author":"Benditz","year":"2023","journal-title":"Z. Rheumatol."},{"key":"ref_82","doi-asserted-by":"crossref","first-page":"618","DOI":"10.1093\/ckj\/sfac009","article-title":"Cardiovascular disease and ANCA-associated vasculitis: Are we missing a beat?","volume":"15","author":"Floyd","year":"2022","journal-title":"Clin. Kidney J."},{"key":"ref_83","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1093\/rheumatology\/kex338","article-title":"Cardiovascular events in anti-neutrophil cytoplasmic antibody-associated vasculitis: A meta-analysis of observational studies","volume":"57","author":"Houben","year":"2018","journal-title":"Rheumatology"},{"key":"ref_84","first-page":"681","article-title":"Association of anti-neutrophil cytoplasmic antibody-associated vasculitis and cardiovascular events: A population-based cohort study","volume":"15","author":"Petrcich","year":"2021","journal-title":"Clin. Kidney J."},{"key":"ref_85","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.atherosclerosis.2021.03.032","article-title":"Cardiovascular events and the role of accelerated atherosclerosis in systemic vasculitis","volume":"325","author":"Clifford","year":"2021","journal-title":"Atherosclerosis"},{"key":"ref_86","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1186\/s13075-020-02321-w","article-title":"The plasma level of mCRP is linked to cardiovascular disease in antineutrophil cytoplasmic antibody-associated vasculitis","volume":"22","author":"Wu","year":"2020","journal-title":"Arthritis Res. Ther."},{"key":"ref_87","doi-asserted-by":"crossref","first-page":"105540","DOI":"10.1016\/j.jbspin.2023.105540","article-title":"Traditional and disease-related cardiovascular risk factors in ANCA-associated vasculitis: A prospective, two-centre cohort study","volume":"90","author":"Vegting","year":"2023","journal-title":"Jt. Bone Spine"},{"key":"ref_88","doi-asserted-by":"crossref","unstructured":"Granel, J., Korkmaz, B., Nouar, D., Weiss, S.A.I., Jenne, D.E., Lemoine, R., and Hoarau, C. (2021). Pathogenicity of Proteinase 3-Anti-Neutrophil Cytoplasmic Antibody in Granulomatosis with Polyangiitis: Implications as Biomarker and Future Therapies. Front. Immunol., 12.","DOI":"10.3389\/fimmu.2021.571933"},{"key":"ref_89","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1007\/s11926-023-01123-8","article-title":"Cardiovascular Disease in Anti-neutrophil Cytoplasm Antibody-Associated Vasculitis","volume":"26","author":"Sayer","year":"2024","journal-title":"Curr. Rheumatol. Rep."}],"container-title":["Diagnostics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2075-4418\/15\/2\/144\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T10:25:41Z","timestamp":1759919141000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2075-4418\/15\/2\/144"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1,9]]},"references-count":89,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2025,1]]}},"alternative-id":["diagnostics15020144"],"URL":"https:\/\/doi.org\/10.3390\/diagnostics15020144","relation":{},"ISSN":["2075-4418"],"issn-type":[{"type":"electronic","value":"2075-4418"}],"subject":[],"published":{"date-parts":[[2025,1,9]]}}}