{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T16:22:34Z","timestamp":1787242954577,"version":"build-2736575974"},"reference-count":10,"publisher":"MDPI AG","issue":"3","license":[{"start":{"date-parts":[[2025,1,23]],"date-time":"2025-01-23T00:00:00Z","timestamp":1737590400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostics"],"abstract":"<jats:p>Long-term abdominal pain (LAP) affects 30% to 40% of children, often linked to functional gastrointestinal disorders (FGIDs) such as functional dyspepsia and irritable bowel syndrome. Less common causes include gastroptosis and superior mesenteric artery (SMA) syndrome, conditions that can be challenging to diagnose due to their rarity. Gastroptosis refers to the downward displacement of the stomach, while SMA syndrome, also known as Wilkie\u2019s syndrome, involves the compression of the duodenum between the abdominal aorta and the superior mesenteric artery. While both conditions have been described separately, their coexistence has not been previously documented. Herein, we present the case of a 17-year-old girl with a six-month history of postprandial abdominal pain and vomiting, diagnosed with both gastroptosis and SMA syndrome. Diagnostic tests, including a CT scan and barium radiography, confirmed the presence of a duodenal stricture and severe gastric elongation, providing an insight into the pathophysiology of these rare conditions.<\/jats:p>","DOI":"10.3390\/diagnostics15030270","type":"journal-article","created":{"date-parts":[[2025,1,23]],"date-time":"2025-01-23T12:24:09Z","timestamp":1737635049000},"page":"270","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["A Two-for-One Diagnosis: A Rare Case of Chronic Abdominal Pain Caused by Gastroptosis and Wilkie\u2019s Syndrome in a Young Woman"],"prefix":"10.3390","volume":"15","author":[{"given":"Nosseir","family":"Youssoufi","sequence":"first","affiliation":[{"name":"General Medicine and Emergency Care Department, CHU Brugmann, 1020 Brussels, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-0766-916X","authenticated-orcid":false,"given":"Ayoub","family":"Jaafari","sequence":"additional","affiliation":[{"name":"Nuclear Medicine and Intensive Care Department, CHU Brugmann, 1020 Brussels, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Soha\u00efb","family":"Mansour","sequence":"additional","affiliation":[{"name":"Cardiology and Intensive Care Department, CHU Saint-Pierre, 1000 Brussels, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamed","family":"El Hamdi","sequence":"additional","affiliation":[{"name":"Gastroenterology Department, CHIREC Hospital Group, 1160 Brussels, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Gallerani","sequence":"additional","affiliation":[{"name":"Intensive Care Deparment, CHU Brugmann, 1020 Brussels, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charalampos","family":"Pierrakos","sequence":"additional","affiliation":[{"name":"Intensive Care Deparment, CHU Brugmann, 1020 Brussels, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rachid","family":"Attou","sequence":"additional","affiliation":[{"name":"Intensive Care Deparment, CHU Brugmann, 1020 Brussels, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,1,23]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"2215","DOI":"10.1097\/j.pain.0000000000003267","article-title":"The prevalence of chronic pain in children and adolescents: A systematic review update and meta-analysis","volume":"165","author":"Chambers","year":"2024","journal-title":"Pain"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"1118","DOI":"10.1016\/j.mayocp.2016.06.003","article-title":"Common functional gastroenterological disorders associated with abdominal pain","volume":"91","author":"Bharucha","year":"2016","journal-title":"Mayo Clin. Proc."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1148\/15.2.223","article-title":"When has visceroptosis clinical significance?","volume":"15","author":"Beilin","year":"1930","journal-title":"Radiology"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1016\/j.ijscr.2019.12.043","article-title":"Historical terminology and superior mesenteric artery syndrome","volume":"67","author":"Yale","year":"2020","journal-title":"Int. J. Surg. Case Rep."},{"key":"ref_5","doi-asserted-by":"crossref","unstructured":"Staszewska, A., Jarzumbek, A., Saran, A., Gierak-Firszt, S., and Kwiecien, J. (2023). Postprandial abdominal pain caused by gastroptosis\u2014A case report. Children, 10.","DOI":"10.3390\/children10010116"},{"key":"ref_6","doi-asserted-by":"crossref","unstructured":"Abenavoli, L., Imoletti, F., Quero, G., Bottino, V., Facciolo, V., Scarlata, G.G.M., Luzza, F., and Lagan\u00e0, D. (2024). The diagnosis of Wilkie\u2019s syndrome associated with Nutcracker syndrome: A case report and literature review. Diagnostics, 14.","DOI":"10.20944\/preprints202406.0919.v1"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"3369","DOI":"10.12998\/wjcc.v11.i15.3369","article-title":"Superior mesenteric artery syndrome: Diagnosis and management","volume":"11","author":"Oka","year":"2023","journal-title":"World J. Clin. Cases"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"1244","DOI":"10.1002\/ca.22249","article-title":"Superior mesenteric artery syndrome and its associated gastrointestinal implications","volume":"27","author":"Mathenge","year":"2013","journal-title":"Clin. Anat."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"14","DOI":"10.17140\/GOJ-2-126","article-title":"The clinical or radiographic diagnosis of gastroptosis: Still relevant?","volume":"2","author":"Klein","year":"2017","journal-title":"Gastro Open J."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1186\/1757-1626-2-184","article-title":"Gastroparesis associated with gastroptosis presenting as a lower abdominal bulking mass in a child: A case report","volume":"2","author":"Christianakis","year":"2009","journal-title":"Cases J."}],"container-title":["Diagnostics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2075-4418\/15\/3\/270\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T10:34:53Z","timestamp":1759919693000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2075-4418\/15\/3\/270"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1,23]]},"references-count":10,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2025,2]]}},"alternative-id":["diagnostics15030270"],"URL":"https:\/\/doi.org\/10.3390\/diagnostics15030270","relation":{},"ISSN":["2075-4418"],"issn-type":[{"value":"2075-4418","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,1,23]]}}}