{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T20:23:09Z","timestamp":1790713389739,"version":"4.1.0"},"reference-count":52,"publisher":"MDPI AG","issue":"3","license":[{"start":{"date-parts":[[2025,2,4]],"date-time":"2025-02-04T00:00:00Z","timestamp":1738627200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostics"],"abstract":"<jats:p>Interstitial lung disease (ILD) is a severe complication of certain connective tissue diseases (CTDs) such as systemic sclerosis (SSc), mixed connective tissue disease (MCTD), idiopathic inflammatory myopathies (IIM), rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE), and it is associated with nailfold videocapillaroscopy (NVC) changes and increased morbidity and mortality rates. Early diagnosis is crucial in order to prevent the progression of ILD, prevent respiratory failure and enhance the patient\u2019s overall quality of life. The most common paraclinical investigations are high-resolution computed tomography (HRCT) and functional respiratory tests such as forced vital capacity (FVC) and the diffusing capacity of the lungs for carbon monoxide (DLCO). The most frequent CTD associated with both ILD and NVC changes is systemic sclerosis. The \u201clate\u201d scleroderma pattern was the most common abnormality identified in NVC results in SSc patients. Other autoimmune diseases were also correlated with ILD and NVC changes, especially when the Raynaud phenomenon was present. Low capillary density was associated with the presence and severity of ILD and a reduction in FVC and DLCO. NVC can also differentiate the capillaroscopic changes in some particular types of ILD, such as the usual interstitial pneumonia (UIP) pattern from the non-specific interstitial pneumonia (NSIP) pattern. Nevertheless, further extensive research is necessary in order to establish the diagnostic value of NVC in CTD-ILD in clinical practice.<\/jats:p>","DOI":"10.3390\/diagnostics15030362","type":"journal-article","created":{"date-parts":[[2025,2,4]],"date-time":"2025-02-04T05:13:43Z","timestamp":1738646023000},"page":"362","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["The Role of Nailfold Videocapillaroscopy in the Diagnosis and Monitoring of Interstitial Lung Disease Associated with Rheumatic Autoimmune Diseases"],"prefix":"10.3390","volume":"15","author":[{"given":"Daniela","family":"Anghel","sequence":"first","affiliation":[{"name":"Department of Internal Medicine 2, Central Military Emergency University Hospital \u2018Dr. Carol Davila\u2019, 010825 Bucharest, Romania"},{"name":"Department of Medico-Surgical and Prophylactic Disciplines, \u2018Titu Maiorescu\u2019 University, 031593 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8070-8495","authenticated-orcid":false,"given":"Oana-Georgiana","family":"Prioteas\u0103","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine 2, Central Military Emergency University Hospital \u2018Dr. Carol Davila\u2019, 010825 Bucharest, Romania"},{"name":"Department of Internal Medicine and Rheumatology, \u2018Carol Davila\u2019 University of Medicine and Pharmacy, 020021 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Iulia-Nadine","family":"Nicolau","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine 2, Central Military Emergency University Hospital \u2018Dr. Carol Davila\u2019, 010825 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S\u0103ndica","family":"Bucuric\u0103","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Central Military Emergency University Hospital \u2018Dr. Carol Davila\u2019, 010825 Bucharest, Romania"},{"name":"Department of Gastroenterology, \u2018Carol Davila\u2019 University of Medicine and Pharmacy, 020021 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3883-9672","authenticated-orcid":false,"given":"Daniela-Opri\u0219","family":"Belinski","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine and Rheumatology, \u2018Carol Davila\u2019 University of Medicine and Pharmacy, 020021 Bucharest, Romania"},{"name":"Department of Rheumatology, \u2018Sf. Maria\u2019 Clinical Hospital, 011172 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gilda-Georgeta","family":"Popescu","sequence":"additional","affiliation":[{"name":"Department of Medico-Surgical and Prophylactic Disciplines, \u2018Titu Maiorescu\u2019 University, 031593 Bucharest, Romania"},{"name":"Tuberculosis Control Subcomission, Romanian Ministry of Health, 030167 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Minerva Claudia","family":"Ghinescu","sequence":"additional","affiliation":[{"name":"Department of Medico-Surgical and Prophylactic Disciplines, \u2018Titu Maiorescu\u2019 University, 031593 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6662-7354","authenticated-orcid":false,"given":"Anca","family":"Bobirc\u0103","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine and Rheumatology, \u2018Carol Davila\u2019 University of Medicine and Pharmacy, 020021 Bucharest, Romania"},{"name":"Department of Internal Medicine and Rheumatology, \u201cDr. Ion Cantacuzino\u201d Clinical Hospital, 011437 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria-Laura","family":"Gro\u0219eanu","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine and Rheumatology, \u2018Carol Davila\u2019 University of Medicine and Pharmacy, 020021 Bucharest, Romania"},{"name":"Department of Rheumatology, \u2018Sf. Maria\u2019 Clinical Hospital, 011172 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Violeta-Claudia","family":"Bojinc\u0103","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine and Rheumatology, \u2018Carol Davila\u2019 University of Medicine and Pharmacy, 020021 Bucharest, Romania"},{"name":"Department of Internal Medicine, \u2018Sf. Maria\u2019 Clinical Hospital, 011172 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,2,4]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"2217","DOI":"10.1093\/rheumatology\/keac102","article-title":"Is there a role for nailfold videocapillaroscopy in interstitial lung disease?","volume":"61","author":"Smith","year":"2022","journal-title":"Rheumatology"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"588","DOI":"10.31138\/mjr.20230804.tr","article-title":"The Role of Nailfold Capillaroscopy in Evaluating Patients with Interstitial Lung Disease Related to Connective Tissue Disease","volume":"4","author":"Venetsanopoulou","year":"2023","journal-title":"Mediterr. J. 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