{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T22:45:44Z","timestamp":1789771544525,"version":"4.0.1"},"reference-count":10,"publisher":"MDPI AG","issue":"5","license":[{"start":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T00:00:00Z","timestamp":1740096000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostics"],"abstract":"<jats:p>Primary cutaneous adenoid cystic carcinoma (PCACC) isa rare skin malignancy first reported in the 1970s with limited number of cases found in the literature. These neoplasms are typically identified in middle-to-older-age individuals and are mostly located in the scalp and neck region but can identified throughout the body. We describe the case of a 67-year-old male patient that presented to our department with a slow-growing nodule in the left gluteal region that turned out to be a PCACC and analyze the differential diagnosis, radiology, histopathological findings and successful treatment with a wide local excision. Current literature on the subject is also presented and discussed.<\/jats:p>","DOI":"10.3390\/diagnostics15050533","type":"journal-article","created":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T12:22:31Z","timestamp":1740140551000},"page":"533","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["A Rare Case of Primary Cutaneous Adenoid Cystic Carcinoma"],"prefix":"10.3390","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-8122-0872","authenticated-orcid":false,"given":"Ioannis","family":"Katsarelas","sequence":"first","affiliation":[{"name":"Department of General Surgery, General Hospital of Katerini, 60100 Katerini, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Afroditi","family":"Kotarela","sequence":"additional","affiliation":[{"name":"Department of General Surgery, General Hospital of Katerini, 60100 Katerini, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5662-9201","authenticated-orcid":false,"given":"Mattheos","family":"Bobos","sequence":"additional","affiliation":[{"name":"Department of Biomedical Sciences, School of Health Sciences, International Hellenic University, Alexandrian Campus, 57400 Thessaloniki, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandra","family":"Panagiotou","sequence":"additional","affiliation":[{"name":"Department of General Surgery, General Hospital of Katerini, 60100 Katerini, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Periklis","family":"Dimasis","sequence":"additional","affiliation":[{"name":"Department of General Surgery, General Hospital of Katerini, 60100 Katerini, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,2,21]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1007\/s00292-001-0516-y","article-title":"Ekkrine Schwei\u00dfdr\u00fcsenkarzinome der Haut","volume":"23","year":"2002","journal-title":"Pathologe"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/j.jaad.2020.08.040","article-title":"Primary cutaneous adenoid cystic carcinoma: Characterizing US demographics, clinical course, and prognostic factors","volume":"85","author":"Yumeen","year":"2020","journal-title":"J. Am. Acad. Dermatol."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1093\/jjco\/hym119","article-title":"Prognostic factors affecting the clinical outcome of adenoid cystic carcinoma of the head and neck","volume":"37","author":"Ko","year":"2007","journal-title":"Jpn. J. Clin. Oncol."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1001\/archderm.1978.01640150057018","article-title":"Primary adenoid cystic carcinoma of skin","volume":"114","author":"Headington","year":"1978","journal-title":"Arch. Dermatol."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1001\/archderm.1975.01630180121024","article-title":"Adenoid cystic carcinoma of scalp","volume":"111","author":"Boggio","year":"1975","journal-title":"Arch. Dermatol."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/j.jaad.2009.07.027","article-title":"Primary cutaneous adenoid cystic carcinoma in the United States: Incidence, survival, and associated cancers, 1976 to 2005","volume":"63","author":"Dores","year":"2010","journal-title":"J. Am. Acad. Dermatol."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"636","DOI":"10.1016\/j.jaad.2007.12.005","article-title":"Primary cutaneous adenoid cystic carcinoma","volume":"58","author":"Naylor","year":"2008","journal-title":"J. Am. Acad. Dermatol."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1111\/cup.12856","article-title":"Primary cutaneous adenoid cystic carcinoma with MYB aberrations: Report of three cases and comprehensive review of the literature","volume":"44","author":"Zhang","year":"2017","journal-title":"J. Cutan. Pathol."},{"key":"ref_9","unstructured":"Homsi, H., and Ronen, S. (2024, November 14). Adenoid Cystic Carcinoma (Primary Cutaneous). PathologyOutlines.com. Available online: https:\/\/www.pathologyoutlines.com\/topic\/skintumornonmelanocyticACC.html."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"469049","DOI":"10.1155\/2010\/469049","article-title":"Cutaneous adenoid cystic carcinoma with perineural invasion treated by Mohs micrographic surgery\u2014A case report with literature review","volume":"2010","author":"Xu","year":"2010","journal-title":"J. Oncol."}],"container-title":["Diagnostics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2075-4418\/15\/5\/533\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T16:40:13Z","timestamp":1760028013000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2075-4418\/15\/5\/533"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2,21]]},"references-count":10,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2025,3]]}},"alternative-id":["diagnostics15050533"],"URL":"https:\/\/doi.org\/10.3390\/diagnostics15050533","relation":{},"ISSN":["2075-4418"],"issn-type":[{"value":"2075-4418","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,2,21]]}}}