{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T01:01:24Z","timestamp":1760058084805,"version":"build-2065373602"},"reference-count":75,"publisher":"MDPI AG","issue":"6","license":[{"start":{"date-parts":[[2025,3,12]],"date-time":"2025-03-12T00:00:00Z","timestamp":1741737600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostics"],"abstract":"<jats:p>Contrast-enhanced US (CEUS) is now widely used to observe the hemodynamics of the liver. The CEUS diagnosis mainly consists of evaluating hepatic artery and portal vein flow changes in liver diseases, but it has not been widely used for the diagnosis of hepatic venous (HV) abnormalities in the clinical setting. For this background, this review tried to reconsider this problem. In short, observing HV CEUS findings, especially HV transit time, serves to largely narrow the differential diagnosis and increase the diagnostic confidence of the CEUS. However, diagnosing HV CEUS diagnosis in a wide range of liver diseases requires understanding of vascular anatomy of the upper abdomen and vascular structure of each disease. Additionally, interpreting CEUS findings of HCC should be prudent, because its drainage vessels change according to the histological progression, from the HV to the portal vein. Thus, the most important way of making use of the CEUS information is interpreting it in conjunction with the clinical data.<\/jats:p>","DOI":"10.3390\/diagnostics15060709","type":"journal-article","created":{"date-parts":[[2025,3,12]],"date-time":"2025-03-12T10:45:06Z","timestamp":1741776306000},"page":"709","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Demonstration of Hepatic Vein Abnormalities Using Contrast-Enhanced Sonography in Liver Diseases"],"prefix":"10.3390","volume":"15","author":[{"given":"Hiroko","family":"Naganuma","sequence":"first","affiliation":[{"name":"Department of Gastroenterology, Yokote Municipal Hospital, Yokote 013-8602, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hideaki","family":"Ishida","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Akita Red Cross Hospital, Akita 010-1495, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2025,3,12]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"856","DOI":"10.1136\/gut.46.6.856","article-title":"CO2 wedged hepatic venography in the evaluation of portal hypertension","volume":"46","author":"Bandi","year":"2000","journal-title":"Gut"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"31","DOI":"10.3233\/CH-221449","article-title":"Modified contrast-enhanced ultrasonography with the new high-resolution examination technique of high frame rate contrast-enhanced ultrasound (HiFR-CEUS) for characterization of liver lesions: First results","volume":"83","author":"Jung","year":"2023","journal-title":"Clin. 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