{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T09:54:16Z","timestamp":1787824456407,"version":"build-2784847793"},"reference-count":24,"publisher":"MDPI AG","issue":"7","license":[{"start":{"date-parts":[[2025,3,25]],"date-time":"2025-03-25T00:00:00Z","timestamp":1742860800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostics"],"abstract":"<jats:p>Background\/Objectives: Percutaneous kidney biopsy (PKB) is a valuable diagnostic tool for evaluating renal masses and suspected renal cancer but carries a risk of hemorrhagic complications. This study aimed to determine whether injecting a hemostatic Gelfoam mixture into the biopsy tract reduces post-procedural bleeding while maintaining diagnostic accuracy. Methods: This retrospective study included 500 patients who underwent PKB at our hospital between 2019 and 2024. Patients were equally divided into two groups: Group A (n = 250) received Gelfoam injection into the biopsy tract, and Group B (n = 250) underwent standard PKB without Gelfoam. Hemorrhagic complications were categorized as mild, mild\u2013moderate, moderate, or severe based on immediate and 4-h post-procedure CT findings. Management protocols included same-day discharge for mild cases (with next-day re-evaluation) and 24-h observation for mild\u2013moderate cases. Results: Group A had significantly fewer moderate\u2013severe hemorrhages compared to Group B (1.3% vs. 4.0%, p = 0.034) and a higher rate of same-day discharge (84% vs. 40%, p &lt; 0.05). These differences led to a notable reduction in total hospitalization days (43 vs. 167) and decreased overall costs. Diagnostic yield was similarly high in both groups (98.5% vs. 97.8%, p = 0.72). Conclusions: Gelfoam injection during PKB effectively reduces hemorrhagic complications and shortens hospital stay without compromising diagnostic accuracy. Routine use of Gelfoam\u2014especially in high-risk patients\u2014is supported by these findings, and further prospective studies are recommended to validate these results.<\/jats:p>","DOI":"10.3390\/diagnostics15070836","type":"journal-article","created":{"date-parts":[[2025,3,25]],"date-time":"2025-03-25T12:18:52Z","timestamp":1742905132000},"page":"836","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Use of Injection of Hemostatic Gelfoam Mixture During Percutaneous Core Biopsy for Renal Tumors: A Comparative Retrospective Study of Outcomes Regarding Bleeding Complications, Hospital Stay, and Diagnostic Yield Accuracy"],"prefix":"10.3390","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2371-1879","authenticated-orcid":false,"given":"Antonios","family":"Michailidis","sequence":"first","affiliation":[{"name":"Interventional Radiology Department, \u201cGeorgios Papanikolaou\u201d General Hospital of Thessaloniki, 57010 Exochi, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Georgia","family":"Mingou","sequence":"additional","affiliation":[{"name":"Interventional Radiology Department, \u201cGeorgios Papanikolaou\u201d General Hospital of Thessaloniki, 57010 Exochi, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eleni","family":"Tsakirmpaloglou","sequence":"additional","affiliation":[{"name":"Interventional Radiology Department, \u201cGeorgios Papanikolaou\u201d General Hospital of Thessaloniki, 57010 Exochi, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-7779-6005","authenticated-orcid":false,"given":"Panagiotis","family":"Kosmoliaptsis","sequence":"additional","affiliation":[{"name":"Interventional Radiology Department, \u201cGeorgios Papanikolaou\u201d General Hospital of Thessaloniki, 57010 Exochi, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danae","family":"Makri","sequence":"additional","affiliation":[{"name":"Interventional Radiology Department, \u201cGeorgios Papanikolaou\u201d General Hospital of Thessaloniki, 57010 Exochi, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ioannis","family":"Papadimitriou","sequence":"additional","affiliation":[{"name":"Interventional Radiology Department, \u201cGeorgios Papanikolaou\u201d General Hospital of Thessaloniki, 57010 Exochi, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-3003-7549","authenticated-orcid":false,"given":"George","family":"Dimou","sequence":"additional","affiliation":[{"name":"Interventional Radiology Department, \u201cGeorgios Papanikolaou\u201d General Hospital of Thessaloniki, 57010 Exochi, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-6380-0878","authenticated-orcid":false,"given":"Christos","family":"Giankoulof","sequence":"additional","affiliation":[{"name":"Interventional Radiology Department, \u201cGeorgios Papanikolaou\u201d General Hospital of Thessaloniki, 57010 Exochi, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6252-1130","authenticated-orcid":false,"given":"Evangelos","family":"Petsatodis","sequence":"additional","affiliation":[{"name":"Interventional Radiology Department, \u201cGeorgios Papanikolaou\u201d General Hospital of Thessaloniki, 57010 Exochi, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,3,25]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1148\/radiology.178.1.1984314","article-title":"Complications of percutaneous abdominal fine-needle biopsy","volume":"178","author":"Smith","year":"1991","journal-title":"Radiology"},{"key":"ref_2","first-page":"107","article-title":"Ultrasound-guided plugged percutaneous biopsy of solid organs in patients with bleeding tendencies","volume":"20","author":"Tsang","year":"2014","journal-title":"Hong Kong Med. 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