{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T01:35:07Z","timestamp":1790300107778,"version":"4.1.0"},"reference-count":40,"publisher":"MDPI AG","issue":"9","license":[{"start":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T00:00:00Z","timestamp":1745366400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostics"],"abstract":"<jats:p>The combination of positron emission tomography (PET) and magnetic resonance imaging (MRI) is a modern, highly advanced diagnostic tool that offers numerous advantages in the treatment and management of some pediatric pathologies. The use of PET\/MR in children provides high-resolution images with outstanding tissue characterization, as well as important metabolic and physiological information; it is not only essential for early diagnosis, but also for the assessment and management of oncological, neurological, and cardiovascular diseases. The hybrid PET\/MR is a multimodal approach that reduces the need for separate examinations, minimizes radiation exposure, and improves the overall experience for pediatric patients. In addition, PET\/MR, by combining functional data, allows for more precise therapeutic planning and monitoring of treatment responses, optimizing clinical interventions especially with regard to staging and follow-up. This review will explore the benefits, weaknesses, and emerging applications of PET\/MR in pediatric patients.<\/jats:p>","DOI":"10.3390\/diagnostics15091070","type":"journal-article","created":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T08:26:43Z","timestamp":1745396803000},"page":"1070","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Will PET\/MR Imaging Replace PET\/CT for Pediatric Applications?"],"prefix":"10.3390","volume":"15","author":[{"given":"Gabriele","family":"Masselli","sequence":"first","affiliation":[{"name":"Department of Radiological Sciences, Oncology and Pathology, Policlinico Umberto I, Sapienza University of Rome, 00161 Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-8960-5998","authenticated-orcid":false,"given":"Chiara","family":"Di Bella","sequence":"additional","affiliation":[{"name":"Department of Radiological Sciences, Oncology and Pathology, Policlinico Umberto I, Sapienza University of Rome, 00161 Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,4,23]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1016\/j.rcl.2011.05.008","article-title":"Imaging modalities in pediatric oncology","volume":"49","author":"States","year":"2011","journal-title":"Radiol. 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