{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T00:17:29Z","timestamp":1790036249002,"version":"4.0.1"},"reference-count":20,"publisher":"MDPI AG","issue":"10","license":[{"start":{"date-parts":[[2025,5,16]],"date-time":"2025-05-16T00:00:00Z","timestamp":1747353600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostics"],"abstract":"<jats:p>Purpose: This study aimed to evaluate the efficacy and safety of the Angio-Seal\u2122 VIP vascular closure device (VCD) in achieving hemostasis following percutaneous transhepatic portal venous interventions. Methods: This retrospective study evaluated 20 patients (mean age: 52.85 \u00b1 16.18 years; 80% male) who underwent percutaneous transhepatic portal vein interventions followed by tract closure with the Angio-Seal\u2122 device between January 2016 and September 2024. Procedural data, pre- and post-procedural hemoglobin and hematocrit levels, and complications were analyzed. Technical success was defined as the successful deployment of the device with immediate hemostasis and no evidence of bleeding on post-procedural imaging. Results: Technical success, as defined in this study, was achieved in all 20 procedures (100%). The mean hemoglobin level declined from 11.91 \u00b1 2.01 g\/dL to 11.09 \u00b1 2.19 g\/dL (p &lt; 0.001), and the mean hematocrit level decreased from 36.18 \u00b1 6.03% to 32.98 \u00b1 5.80% (p = 0.001). A hemoglobin drop \u22652 g\/dL occurred in two patients (10%) and a hematocrit drop \u22654% in six patients (30%); none were associated with imaging or clinical evidence of hemorrhage. No major complications were observed. Minor complications, including localized pain managed with analgesics, occurred in five patients (25%). Follow-up imaging confirmed the absence of hemoperitoneum or device-related failure. Conclusions: Angio-Seal\u2122 is a technically feasible, safe, and effective option for tract closure following percutaneous transhepatic portal vein access. This single-device approach may offer a cost-effective alternative to traditional embolization techniques. However, more extensive prospective studies are required to validate these findings.<\/jats:p>","DOI":"10.3390\/diagnostics15101266","type":"journal-article","created":{"date-parts":[[2025,5,16]],"date-time":"2025-05-16T06:57:28Z","timestamp":1747378648000},"page":"1266","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Single Angio-Seal\u2122 Device as a Simplified and Technically Feasible Alternative for Tract Closure in Percutaneous Portal Vein Access: A Retrospective Study"],"prefix":"10.3390","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5760-1777","authenticated-orcid":false,"given":"Ismail","family":"Karluka","sequence":"first","affiliation":[{"name":"Department of Interventional Radiology, Adana Dr. Turgut Noyan Application and Research Center, Baskent University, Adana 01250, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1142-213X","authenticated-orcid":false,"given":"Mustafa","family":"Maz\u0131can","sequence":"additional","affiliation":[{"name":"Department of Interventional Radiology, Adana Dr. Turgut Noyan Application and Research Center, Baskent University, Adana 01250, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,5,16]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"20140347","DOI":"10.1259\/bjr.20140347","article-title":"Embolization of percutaneous transhepatic portal venous access tract with N-butyl cyanoacrylate","volume":"87","author":"Park","year":"2014","journal-title":"Br. 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