{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T01:22:55Z","timestamp":1760059375001,"version":"build-2065373602"},"reference-count":37,"publisher":"MDPI AG","issue":"12","license":[{"start":{"date-parts":[[2025,6,10]],"date-time":"2025-06-10T00:00:00Z","timestamp":1749513600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Taiwan and Mongolia joint project","award":["TWN-2-2022\/03","NSTC 112-2923-B-037-002-MY3"],"award-info":[{"award-number":["TWN-2-2022\/03","NSTC 112-2923-B-037-002-MY3"]}]},{"name":"National Science and Technology Council of Taiwan","award":["TWN-2-2022\/03","NSTC 112-2923-B-037-002-MY3"],"award-info":[{"award-number":["TWN-2-2022\/03","NSTC 112-2923-B-037-002-MY3"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostics"],"abstract":"<jats:p>Background: According to a study conducted among a relatively healthy population of Mongolia (2017), the prevalence of hepatitis C virus (HCV) infection is 8.5%, which is considered a high prevalence of this infection. In addition to inflammation of the liver, other organ systems are affected by HCV infection, according to research. Our study aimed to evaluate renal dysfunction in patients with HCV infection. Methods: In the study, 111 people with chronic hepatitis C virus infection were included in the study group, and 111 relatively healthy people were included in the control group. Laboratory parameters were analyzed. Liver fibrosis score was assessed and evaluated by renal function. Results: There were 22.9% (51) men and 77.1% (171) women among the 222 participants, and the average age was 40.7 \u00b1 11.1 years. The glomerular filtration rate was 105.3 \u00b1 24.5 in the chronic hepatitis C virus-infected group and 118.7 \u00b1 18.5 in the control group, or the statistically significant difference in the case group compared to the control group was p &lt; 0.01. The liver fibrosis score was higher in the case group than in the control group. According to logistic regression analysis, patients with hepatitis C virus infection are 25 times more likely to have a decrease in glomerular filtration rate than those without viral infection (OR 24.91, 95% CI 3.13\u2013198.38, p = 0.002). Conclusions: Our study showed that HCV infection leads to kidney function loss. In addition, older age, obesity, and severe liver fibrosis contribute to kidney function decline.<\/jats:p>","DOI":"10.3390\/diagnostics15121471","type":"journal-article","created":{"date-parts":[[2025,6,10]],"date-time":"2025-06-10T03:54:18Z","timestamp":1749527658000},"page":"1471","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Renal Function in Chronic Hepatitis C Patients in Mongolia"],"prefix":"10.3390","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-5658-6762","authenticated-orcid":false,"given":"Gantogtokh","family":"Dashjamts","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, Institute of Medical Sciences, Ministry of Economy and Development, Ulaanbaatar 14210, Mongolia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amin-Erdene","family":"Ganzorig","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Institute of Medical Sciences, Ministry of Economy and Development, Ulaanbaatar 14210, Mongolia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-1512-4055","authenticated-orcid":false,"given":"Yumchinsuren","family":"Tsedendorj","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Institute of Medical Sciences, Ministry of Economy and Development, Ulaanbaatar 14210, Mongolia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ankhzaya","family":"Batsaikhan","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Institute of Medical Sciences, Ministry of Economy and Development, Ulaanbaatar 14210, Mongolia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3539-951X","authenticated-orcid":false,"given":"Dolgion","family":"Daramjav","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Institute of Medical Sciences, Ministry of Economy and Development, Ulaanbaatar 14210, Mongolia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Enkhmend","family":"Khayankhyarvaa","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Institute of Medical Sciences, Ministry of Economy and Development, Ulaanbaatar 14210, Mongolia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bolor","family":"Ulziitsogt","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Institute of Medical Sciences, Ministry of Economy and Development, Ulaanbaatar 14210, Mongolia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Otgongerel","family":"Nergui","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Institute of Medical Sciences, Ministry of Economy and Development, Ulaanbaatar 14210, Mongolia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nomin-Erdene","family":"Davaasuren","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Institute of Medical Sciences, Ministry of Economy and Development, Ulaanbaatar 14210, Mongolia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6314-6996","authenticated-orcid":false,"given":"Ganchimeg","family":"Dondov","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Institute of Medical Sciences, Ministry of Economy and Development, Ulaanbaatar 14210, Mongolia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9982-949X","authenticated-orcid":false,"given":"Tegshjargal","family":"Badamjav","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Institute of Medical Sciences, Ministry of Economy and Development, Ulaanbaatar 14210, Mongolia"},{"name":"Department of Biological Sciences, School of Life Sciences, Inner Mongolia University, Hohhot 010031, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tulgaa","family":"Lonjid","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Institute of Medical Sciences, Ministry of Economy and Development, Ulaanbaatar 14210, Mongolia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chung-Feng","family":"Huang","sequence":"additional","affiliation":[{"name":"Hepatobiliary Division, Department of Internal Medicine, Department of Occupational and Environmental Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung 807378, Taiwan"},{"name":"College of Medicine, Drug Development and Value Creation Research Center, Kaohsiung Medical University, Kaohsiung 807378, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tzu-Chun","family":"Lin","sequence":"additional","affiliation":[{"name":"Hepatobiliary Division, Department of Internal Medicine, Department of Occupational and Environmental Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung 807378, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3109-2166","authenticated-orcid":false,"given":"Batbold","family":"Batsaikhan","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Institute of Medical Sciences, Ministry of Economy and Development, Ulaanbaatar 14210, Mongolia"},{"name":"Department of Health Research, Graduate School, Mongolian National University of Medical Sciences, Ulaanbaatar 14210, Mongolia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2296-3054","authenticated-orcid":false,"given":"Chia-Yen","family":"Dai","sequence":"additional","affiliation":[{"name":"Hepatobiliary Division, Department of Internal Medicine, Department of Occupational and Environmental Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung 807378, Taiwan"},{"name":"College of Medicine, Drug Development and Value Creation Research Center, Kaohsiung Medical University, Kaohsiung 807378, Taiwan"},{"name":"Department of Biological Science and Technology, College of Biological Science and Technology, National Yang Ming Chiao Tung University, Hsinchu 30044, Taiwan"},{"name":"College of Professional Studies, National Pingtung University of Science and Technology, Pingtung 91201, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2025,6,10]]},"reference":[{"key":"ref_1","unstructured":"The Polaris Observatory HCV Collaborators (2017). 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