{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T01:26:22Z","timestamp":1760059582394,"version":"build-2065373602"},"reference-count":28,"publisher":"MDPI AG","issue":"13","license":[{"start":{"date-parts":[[2025,6,26]],"date-time":"2025-06-26T00:00:00Z","timestamp":1750896000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003392","name":"Natural Science Foundation of Fujian Province","doi-asserted-by":"publisher","award":["2021J01275","Y24013"],"award-info":[{"award-number":["2021J01275","Y24013"]}],"id":[{"id":"10.13039\/501100003392","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Graduate Education and Teaching Research Project of Fujian Medical University","award":["2021J01275","Y24013"],"award-info":[{"award-number":["2021J01275","Y24013"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostics"],"abstract":"<jats:p>Background: Stress urinary incontinence (SUI) is frequently underrecognized in late pregnancy, with limited tools for effective risk assessment. This study aimed to evaluate the predictive value of clinical and pelvic floor ultrasound parameters for SUI and construct a validated risk model. Methods: Clinical, obstetric, and pelvic floor ultrasound findings were collected from a total of 521 women in late pregnancy who were enrolled in the study. Based on follow-up results, participants were categorized into SUI and non-SUI groups. Logistic regression analyses were used to identify independent risk factors for SUI, which were incorporated into a nomogram. Results: Four independent predictors were identified: vaginal delivery history (odds ratio [OR] = 2.320), bladder neck funneling (OR = 2.349), bladder neck descent (OR = 1.891), and pubococcygeus muscle contraction strain rate (OR &lt; 0.001). The nomogram achieved an AUC of 0.817 (95% CI: 0.770\u20130.863) in the training set and 0.761 (95% CI: 0.677\u20130.845) in the test set. Conclusions: The nomogram based on clinical and pelvic floor ultrasound parameters accurately predicts the risk of SUI during late pregnancy, offering a useful tool for early identification and personalized management.<\/jats:p>","DOI":"10.3390\/diagnostics15131630","type":"journal-article","created":{"date-parts":[[2025,6,26]],"date-time":"2025-06-26T11:15:23Z","timestamp":1750936523000},"page":"1630","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Construction and Evaluation of a Risk Prediction Model for Stress Urinary Incontinence in Late Pregnancy Based on Clinical Factors and Pelvic Floor Ultrasound Parameters"],"prefix":"10.3390","volume":"15","author":[{"given":"Shunlan","family":"Liu","sequence":"first","affiliation":[{"name":"Department of Ultrasound Medicine, Second Affiliated Hospital of Fujian Medical University, Quanzhou 362000, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aizhi","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Ultrasound Medicine, Nanan Hospital, Quanzhou 362300, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yubing","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Ultrasound Medicine, Second Affiliated Hospital of Fujian Medical University, Quanzhou 362000, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Linlin","family":"Hu","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Second Affiliated Hospital of Fujian Medical University, Quanzhou 362000, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lihong","family":"Cai","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Second Affiliated Hospital of Fujian Medical University, Quanzhou 362000, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shaozheng","family":"He","sequence":"additional","affiliation":[{"name":"Department of Ultrasound Medicine, Second Affiliated Hospital of Fujian Medical University, Quanzhou 362000, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3123-1138","authenticated-orcid":false,"given":"Guorong","family":"Lyu","sequence":"additional","affiliation":[{"name":"Department of Ultrasound Medicine, Second Affiliated Hospital of Fujian Medical University, Quanzhou 362000, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xihua","family":"Lian","sequence":"additional","affiliation":[{"name":"Department of Ultrasound Medicine, Second Affiliated Hospital of Fujian Medical University, Quanzhou 362000, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2025,6,26]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1633","DOI":"10.1007\/s00192-020-04636-3","article-title":"Prevalence, incidence and bothersomeness of urinary incontinence in pregnancy: A systematic review and meta-analysis","volume":"32","author":"Berghmans","year":"2021","journal-title":"Int. Urogynecol. J."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"e37988","DOI":"10.1016\/j.heliyon.2024.e37988","article-title":"Prediction models for postpartum stress urinary incontinence: A systematic review","volume":"10","author":"Wang","year":"2024","journal-title":"Heliyon"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"2129","DOI":"10.1007\/s43032-020-00254-y","article-title":"Risk Factors for Postpartum Stress Urinary Incontinence: A Systematic Review and Meta-analysis","volume":"27","author":"Wang","year":"2020","journal-title":"Reprod. Sci."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"1107","DOI":"10.1111\/j.1471-0528.2003.02415.x","article-title":"Stress incontinence and pelvic floor neurophysiology 15 years after the first delivery","volume":"110","author":"Dolan","year":"2003","journal-title":"BJOG"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/j.jphys.2021.03.001","article-title":"Group-based pelvic floor muscle training for all women during pregnancy is more cost-effective than postnatal training for women with urinary incontinence: Cost-effectiveness analysis of a systematic review","volume":"67","author":"Brennen","year":"2021","journal-title":"J. Physiother."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"1407","DOI":"10.1007\/s00192-021-04960-2","article-title":"The effectiveness of group-based pelvic floor muscle training in preventing and treating urinary incontinence for antenatal and postnatal women: A systematic review","volume":"33","author":"Yang","year":"2022","journal-title":"Int. Urogynecol. J."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"1015","DOI":"10.1111\/aogs.14744","article-title":"Influence of pelvic floor muscle training alone or as part of a general physical activity program during pregnancy on urinary incontinence, episiotomy and third- or fourth-degree perineal tear: Systematic review and meta-analysis of randomized clinical trials","volume":"103","author":"Zhang","year":"2024","journal-title":"Acta Obstet. Gynecol. Scand."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"1557","DOI":"10.1007\/s00192-021-05028-x","article-title":"Antenatal pelvic floor muscle training and urinary incontinence: A randomized controlled 7-year follow-up study","volume":"33","author":"Stafne","year":"2022","journal-title":"Int. Urogynecol J."},{"key":"ref_9","doi-asserted-by":"crossref","unstructured":"Tesemma, M.G., Sori, D.A., and Hajito, K.W. (2024). Prevalence of urinary incontinence and associated factors, its impact on quality of life among pregnant women attending antenatal care at Asella teaching and referral hospital. BMC Urol., 24.","DOI":"10.1186\/s12894-024-01560-2"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"2193","DOI":"10.1111\/aogs.14275","article-title":"Stress and urgency urinary incontinence one year after a first birth-prevalence and risk factors. A prospective cohort study","volume":"100","author":"Jansson","year":"2021","journal-title":"Acta Obstet. Gynecol. Scand."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"20503121231206927","DOI":"10.1177\/20503121231206927","article-title":"Urinary and anal incontinence in pregnancy in a Nigerian population: A prospective longitudinal study","volume":"11","author":"Ugwu","year":"2023","journal-title":"SAGE Open Med."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1016\/j.ogc.2021.05.014","article-title":"Ultrasonographic Imaging of the Pelvic Floor","volume":"48","author":"Pham","year":"2021","journal-title":"Obstet. Gynecol. Clin. N. Am."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"1149","DOI":"10.2147\/IJWH.S361755","article-title":"Application of Transperineal Pelvic Floor Ultrasound in Changes of Pelvic Floor Structure and Function Between Pregnant and Non-Pregnant Women","volume":"14","author":"Xu","year":"2022","journal-title":"Int. J. Womens Health"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"1093","DOI":"10.1055\/s-0034-1383044","article-title":"Interdisciplinary S2k Guideline: Sonography in Urogynecology: Short Version-AWMF Registry Number: 015\/055","volume":"74","author":"Tunn","year":"2014","journal-title":"Geburtshilfe Frauenheilkd."},{"key":"ref_15","doi-asserted-by":"crossref","unstructured":"American Institute of Ultrasound in Medicine (AIUM), American College of Radiology (ACR), American Urogynecologic Society (AUGS), and American Urological Association (AUA), Society of Radiologists in Ultrasound (SRU), International Urogynecological Association (IUGA) (2019). AIUM\/IUGA Practice Parameter for the Performance of Urogynecological Ultrasound Examinations: Developed in Collaboration with the ACR, the AUGS, the AUA, and the SRU. J. Ultrasound Med., 38, 851\u2013864.","DOI":"10.1002\/jum.14953"},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1198\/jasa.2003.s263","article-title":"Regression Modeling Strategies: With Applications to Linear Models, Logistic Regression, and Survival Analysis","volume":"98","author":"Rao","year":"2005","journal-title":"J. Am. Stat. Assoc."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/S0090-4295(02)02243-4","article-title":"The standardisation of terminology in lower urinary tract function: Report from the standardisation sub-committee of the International Continence Society","volume":"61","author":"Abrams","year":"2003","journal-title":"Urology"},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"2190","DOI":"10.1007\/s43032-022-00946-7","article-title":"Hormonal Influence in Stress Urinary Incontinence During Pregnancy and Postpartum","volume":"29","author":"Cuadras","year":"2022","journal-title":"Reprod. Sci."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1002\/nau.25364","article-title":"Development and internal validation of a risk prediction model for stress urinary incontinence throughout pregnancy: A multicenter retrospective longitudinal study in Indonesia","volume":"43","author":"Liang","year":"2024","journal-title":"Neurourol. Urodyn."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"1460","DOI":"10.1111\/j.1471-0528.2000.tb11669.x","article-title":"The prevalence of pelvic floor disorders and their relationship to gender, age, parity and mode of delivery","volume":"107","author":"MacLennan","year":"2000","journal-title":"BJOG"},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1002\/uog.11214","article-title":"Three-dimensional ultrasound of pelvic floor: Is there a correlation with delivery mode and persisting pelvic floor disorders 18\u201324 months after first delivery?","volume":"41","author":"Falkert","year":"2013","journal-title":"Ultrasound Obstet. Gynecol."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"1849","DOI":"10.1007\/s00192-022-05440-x","article-title":"Impact of parity and delivery mode on pelvic floor function in young women: A 3D ultrasound evaluation","volume":"34","author":"Grinbaum","year":"2023","journal-title":"Int. Urogynecol J."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"1163","DOI":"10.2214\/AJR.18.20893","article-title":"Can Stress Urinary Incontinence Be Predicted by Ultrasound?","volume":"213","author":"Xiao","year":"2019","journal-title":"AJR Am. J. Roentgenol."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"2423","DOI":"10.1007\/s00192-024-05931-z","article-title":"Pelvic Floor Ultrasound Findings and Symptoms of Pelvic Floor Dysfunction During Pregnancy","volume":"35","author":"Cattani","year":"2024","journal-title":"Int. Urogynecol J."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1002\/uog.5219","article-title":"New imaging method for assessing pelvic floor biomechanics","volume":"31","author":"Thyer","year":"2008","journal-title":"Ultrasound Obstet. Gynecol."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"966","DOI":"10.1111\/aogs.13368","article-title":"Predicting stress urinary incontinence during pregnancy: Combination of pelvic floor ultrasound parameters and clinical factors","volume":"97","author":"Chen","year":"2018","journal-title":"Acta Obstet. Gynecol. Scand."},{"key":"ref_27","doi-asserted-by":"crossref","unstructured":"Collins, G.S., de Groot, J.A., Dutton, S., Omar, O., Shanyinde, M., Tajar, A., Voysey, M., Wharton, R., Yu, L.M., and Moons, K.G. (2014). External validation of multivariable prediction models: A systematic review of methodological conduct and reporting. BMC Med. Res. Methodol., 14.","DOI":"10.1186\/1471-2288-14-40"},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"983","DOI":"10.1093\/jamia\/ocac002","article-title":"Trends in the conduct and reporting of clinical prediction model development and validation: A systematic review","volume":"29","author":"Yang","year":"2022","journal-title":"J. Am. Med. Inform. Assoc."}],"container-title":["Diagnostics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2075-4418\/15\/13\/1630\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T17:59:27Z","timestamp":1760032767000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2075-4418\/15\/13\/1630"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6,26]]},"references-count":28,"journal-issue":{"issue":"13","published-online":{"date-parts":[[2025,7]]}},"alternative-id":["diagnostics15131630"],"URL":"https:\/\/doi.org\/10.3390\/diagnostics15131630","relation":{},"ISSN":["2075-4418"],"issn-type":[{"type":"electronic","value":"2075-4418"}],"subject":[],"published":{"date-parts":[[2025,6,26]]}}}