{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T04:38:56Z","timestamp":1787027936370,"version":"build-2736575974"},"reference-count":36,"publisher":"MDPI AG","issue":"13","license":[{"start":{"date-parts":[[2025,6,29]],"date-time":"2025-06-29T00:00:00Z","timestamp":1751155200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostics"],"abstract":"<jats:p>Background: Prognostic scoring systems are applied in intensive care units (ICUs) to monitor patients\u2019 responses to treatment and guide treatment modalities. These scoring systems are also used as predictors in sepsis, where mortality rates are high. This study aims to compare the scores (APACHE II, SOFA, SAPS II, OASIS) in terms of their role in predicting overall mortality in patients admitted to ICUs with a diagnosis of sepsis or septic shock. Methods: Among 740 patients admitted to the tertiary intensive care unit within a 2-year period, 165 patients diagnosed with sepsis and septic shock were included in the study. Demographic data, comorbidities, SOFA, SAPSII, OASIS, and APACHE II scores, invasive or noninvasive mechanical ventilation requirements and durations, ICU admissions, hospital stays, and 28-day mortalities were retrospectively evaluated. Results: All scoring systems were positively correlated with mortality and CCI score. SAPS II and OASIS showed a higher correlation with mortality compared to other scoring systems, correlated with ICU admission and mechanical ventilation, unlike other scoring systems. The AUC values for the APACHE II, SOFA, SAPS II, and OASIS were 0.803, 0.873, 0.902, and 0.879, respectively. No statistically significant difference was found between the scores (p &gt; 0.05). Conclusions: Compared to commonly used scoring systems, OASIS is a practical tool and serves as a robust scoring system for assessing mortality in ICU patients diagnosed with sepsis.<\/jats:p>","DOI":"10.3390\/diagnostics15131660","type":"journal-article","created":{"date-parts":[[2025,6,30]],"date-time":"2025-06-30T05:00:37Z","timestamp":1751259637000},"page":"1660","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Comparison of Intensive Care Scoring Systems in Predicting Overall Mortality of Sepsis"],"prefix":"10.3390","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9449-9302","authenticated-orcid":false,"given":"Mustafa Ozgur","family":"Cirik","sequence":"first","affiliation":[{"name":"Department of Anesthesiology and Reanimation, Ankara Ataturk Sanatorium Training and Research Hospital, University of Health Sciences, Sanatoryum St., Kecioren 06290, Ankara, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2420-7607","authenticated-orcid":false,"given":"Guler Eraslan","family":"Doganay","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Reanimation, Ankara Ataturk Sanatorium Training and Research Hospital, University of Health Sciences, Sanatoryum St., Kecioren 06290, Ankara, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3710-4570","authenticated-orcid":false,"given":"Melek","family":"Doganci","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Reanimation, Ankara Ataturk Sanatorium Training and Research Hospital, University of Health Sciences, Sanatoryum St., Kecioren 06290, Ankara, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tarkan","family":"Ozdemir","sequence":"additional","affiliation":[{"name":"Department of Pulmonology, Ankara Ataturk Sanatorium Training and Research Hospital, University of Health Sciences, Sanatoryum St., Kecioren 06290, Ankara, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Murat","family":"Yildiz","sequence":"additional","affiliation":[{"name":"Department of Pulmonology, Ankara Ataturk Sanatorium Training and Research Hospital, University of Health Sciences, Sanatoryum St., Kecioren 06290, Ankara, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5397-8841","authenticated-orcid":false,"given":"Abdullah","family":"Kahraman","sequence":"additional","affiliation":[{"name":"Anesthesiology and Reanimation Intensive Care Unit, Ministry of Health Ankara Etlik City Hospital, Kecioren 06170, Ankara, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1474-5591","authenticated-orcid":false,"given":"Seray","family":"Hazer","sequence":"additional","affiliation":[{"name":"Department of Thorasic Surgery, Ankara Ataturk Sanatorium Training and Research Hospital, University of Health Sciences, Sanatoryum St., Kecioren 06290, Ankara, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mehtap","family":"Tunc","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Reanimation, Ankara Ataturk Sanatorium Training and Research Hospital, University of Health Sciences, Sanatoryum St., Kecioren 06290, Ankara, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0968-1549","authenticated-orcid":false,"given":"Kerem","family":"Ensarioglu","sequence":"additional","affiliation":[{"name":"Department of Pulmonology, Ankara Ataturk Sanatorium Training and Research Hospital, University of Health Sciences, Sanatoryum St., Kecioren 06290, Ankara, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8003-1170","authenticated-orcid":false,"given":"Azra","family":"Ozanbarci","sequence":"additional","affiliation":[{"name":"Anesthesiology and Reanimation Intensive Care Unit, Ministry of Health Ankara Etlik City Hospital, Kecioren 06170, Ankara, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3599-2719","authenticated-orcid":false,"given":"Oral","family":"Mentes","sequence":"additional","affiliation":[{"name":"Intensive Care Unit, Gulhane Training and Research Hospital, University of Health Sciences, Kecioren 06010, Ankara, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,6,29]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.ejim.2017.02.013","article-title":"A new method to predict hospital mortality in severe community acquired pneumonia","volume":"40","author":"Wang","year":"2017","journal-title":"Eur. 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