{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T01:05:06Z","timestamp":1792803906207,"version":"4.5.0"},"reference-count":35,"publisher":"MDPI AG","issue":"16","license":[{"start":{"date-parts":[[2025,8,12]],"date-time":"2025-08-12T00:00:00Z","timestamp":1754956800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"the University of Oradea","id":[{"id":"https:\/\/ror.org\/00wzhv093","id-type":"ROR","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostics"],"abstract":"<jats:p>Background: Gallstone ileus is a rare cause of bowel obstruction, often presenting with nonspecific symptoms that delay diagnosis. This study assessed the diagnostic value of CT imaging and its correlation with histopathological findings in confirmed cases. Methods: A retrospective analysis of 14 patients with surgically confirmed gallstone ileus was performed. All underwent abdominal radiography, ultrasound, and CT. Imaging findings were evaluated for calcification type, impaction site, and fistula presence. Histopathology from surgical specimens was used for correlation. Relative risk (RR) and 95% confidence intervals (CIs) were calculated, with adjustments for small sample size. Results: Rim-calcified gallstones were the most common (50%) and significantly associated with chronic inflammation (RR 1.42, 95% CI: 1.05\u20131.93). Cholecystoduodenal fistulas were most frequent (57.1%), with a 92.8% imaging-pathology concordance. Ileal impaction (35.7%) was linked to increased risk of bowel necrosis (RR 2.0, 95% CI: 1.1\u20133.6). All stones were &gt;3 cm; two patients had recurrence. No perioperative mortality occurred. Conclusions: CT imaging demonstrates high diagnostic accuracy and strong correlation with histopathological findings in gallstone ileus. Identifying calcification patterns and impaction sites aids early diagnosis and surgical planning.<\/jats:p>","DOI":"10.3390\/diagnostics15162017","type":"journal-article","created":{"date-parts":[[2025,8,12]],"date-time":"2025-08-12T07:53:44Z","timestamp":1754985224000},"page":"2017","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Diagnostic Value of Multimodal Imaging and Histopathology in Gallstone Ileus: A Retrospective Analysis"],"prefix":"10.3390","volume":"15","author":[{"given":"Alina Cristiana","family":"Venter","sequence":"first","affiliation":[{"name":"Department of Morphological Disciplines, Faculty of Medicine and Pharmacy, University of Oradea, 410073 Oradea, Romania"},{"name":"Radiology Clinic, Emergency County Clinical Hospital of Bihor, 410165 Oradea, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1405-6836","authenticated-orcid":false,"given":"Ovidiu","family":"\u021aica","sequence":"additional","affiliation":[{"name":"Department of Morphological Disciplines, Faculty of Medicine and Pharmacy, University of Oradea, 410073 Oradea, Romania"},{"name":"Department of Pathology, Emergency County Clinical Hospital of Bihor, 410165 Oradea, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrada","family":"Cheseli","sequence":"additional","affiliation":[{"name":"Radiology Clinic, Emergency County Clinical Hospital of Bihor, 410165 Oradea, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cristian Marius","family":"Daina","sequence":"additional","affiliation":[{"name":"Department of Surgical Disciplines, Faculty of Medicine and Pharmacy, University of Oradea, 410073 Oradea, Romania"},{"name":"Clinic of Anaesthesiology and Intensive Care, Emergency County Clinical Hospital of Bihor, 410165 Oradea, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ioan George","family":"Oswald","sequence":"additional","affiliation":[{"name":"Radiology Clinic, Emergency County Clinical Hospital of Bihor, 410165 Oradea, Romania"},{"name":"Department of Preclinical Disciplines, Faculty of Medicine and Pharmacy, University of Oradea, 410073 Oradea, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Corina","family":"Beiu\u0219anu","sequence":"additional","affiliation":[{"name":"Department of Morphological Disciplines, Faculty of Medicine and Pharmacy, University of Oradea, 410073 Oradea, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ginetta","family":"Andreescu","sequence":"additional","affiliation":[{"name":"Department of Morphological Disciplines, Faculty of Medicine and Pharmacy, University of Oradea, 410073 Oradea, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ilarie","family":"Brihan","sequence":"additional","affiliation":[{"name":"Department of Psycho-Neurosciences, and Recovery, Faculty of Medicine and Pharmacy, University of Oradea, 410073 Oradea, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,8,12]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1007\/s10140-017-1568-5","article-title":"Clinical and radiological diagnosis of gallstone ileus: A mini review","volume":"25","author":"Chang","year":"2018","journal-title":"Emerg. 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