{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T01:39:21Z","timestamp":1760060361353,"version":"build-2065373602"},"reference-count":31,"publisher":"MDPI AG","issue":"17","license":[{"start":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T00:00:00Z","timestamp":1756252800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Chungnam National University","award":["RS-2024-00355990"],"award-info":[{"award-number":["RS-2024-00355990"]}]},{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea (NRF) grant funded by the Korean government (MSIT)","doi-asserted-by":"publisher","award":["RS-2024-00355990"],"award-info":[{"award-number":["RS-2024-00355990"]}],"id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostics"],"abstract":"<jats:p>Background\/Objectives: Benign paroxysmal positional vertigo (BPPV) is one of the most common vestibular disorders and is characterized by transient but very severe vertigo, increasing fall risk, especially in older people. While many risk factors have been reported, there are still contradicting papers and evidence from large-scale studies remains limited. Methods: This nationwide, nested case\u2013control study utilized Korean National Health Insurance Service-Health Screening Cohort data to investigate possible risk factors for BPPV. In particular, it examined the association between prior head trauma and BPPV, proposing prior head trauma as a plausible and clinically relevant risk factor. From an initial cohort of 514,866 participants, 29,467 BPPV cases were matched 1:4 with 117,868 controls based on age, sex, income, region, and index date. Conditional logistic regression, with overlap weighting, assessed the risk of BPPV associated with head trauma and other potential factors. Results: Head trauma was modestly more prevalent in the BPPV group (2.29% vs. 1.83%) and was significantly associated with BPPV (adjusted OR 1.28, 95% CI 1.17\u20131.40, p &lt; 0.001). The corresponding Absolute Risk Increase (ARI) was 0.82 percentage points over the entire follow-up and 0.66 percentage points within 1 year. The association persisted across most subgroups including both demographic and clinical factors except underweight individuals and those with high comorbidity scores. Conclusions: This large-scale analysis reinforces head trauma as a significant risk factor for BPPV, providing population-level evidence that may guide clinical assessment and prevention strategies.<\/jats:p>","DOI":"10.3390\/diagnostics15172171","type":"journal-article","created":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T15:49:34Z","timestamp":1756309774000},"page":"2171","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["The Association Between Head Trauma and BPPV: A Nested Case-Control Study Using a National Health Screening Cohort"],"prefix":"10.3390","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2511-5536","authenticated-orcid":false,"given":"Dae Myoung","family":"Yoo","sequence":"first","affiliation":[{"name":"Hallym Data Science Laboratory, College of Medicine, Hallym University, Anyang 14068, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bo-Ram","family":"Yang","sequence":"additional","affiliation":[{"name":"College of Pharmacy, Chungnam National University, Daejeon 34134, Republic of Korea"},{"name":"Department of Bio-AI Convergence, Chungnam National University, Daejeon 34134, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-2849-9735","authenticated-orcid":false,"given":"Kyeongmin","family":"Han","sequence":"additional","affiliation":[{"name":"Hallym Data Science Laboratory, College of Medicine, Hallym University, Anyang 14068, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1655-9549","authenticated-orcid":false,"given":"Hyo Geun","family":"Choi","sequence":"additional","affiliation":[{"name":"Suseoseoulent Clinic, Seoul 06349, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3839-2324","authenticated-orcid":false,"given":"Goun","family":"Choe","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology-Head and Neck Surgery, College of Medicine, Chungnam National University, Chungnam National University Sejong Hospital, Daejeon 35015, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3101-6841","authenticated-orcid":false,"given":"Jin Woong","family":"Choi","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology-Head and Neck Surgery, College of Medicine, Chungnam National University, Chungnam National University Hospital, Daejeon 35015, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bong Jik","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology-Head and Neck Surgery, College of Medicine, Chungnam National University, Chungnam National University Sejong Hospital, Daejeon 35015, Republic of Korea"},{"name":"Brain Research Institute, College of Medicine, Chungnam National University, Daejeon 35015, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2025,8,27]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"253","DOI":"10.3233\/VES-190667","article-title":"Clinical characteristics and associated factors of canal switch in benign paroxysmal positional vertigo","volume":"29","author":"Lee","year":"2019","journal-title":"J. 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