{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T19:40:12Z","timestamp":1789501212449,"version":"build-2803163510"},"reference-count":29,"publisher":"MDPI AG","issue":"23","license":[{"start":{"date-parts":[[2025,11,29]],"date-time":"2025-11-29T00:00:00Z","timestamp":1764374400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostics"],"abstract":"<jats:p>Background\/Objectives: Despite the complementary insights provided by body plethysmography and impulse oscillometry, direct comparisons across obstructive and restrictive lung diseases remain limited. The aim of this study was to evaluate correlations between plethysmographic and oscillometric parameters, with a particular focus on hyperinflation and small airway dysfunction. Methods: We retrospectively analyzed 69 adult patients (35 obstructive, 34 restrictive) hospitalized in the Pulmonology Department of Mure\u0219 Clinical Hospital. All patients underwent body plethysmography (sRaw, Rtot, FRC, RV, TLC, RV\/TLC) and impulse oscillometry (R5, R20, R5-20, X5, Fres, AX). Non-parametric tests were used to compare groups, and associations were assessed using Spearman\u2019s correlation. Results: Higher airway resistance (sRaw 124 vs. 62, p &lt; 0.001; R5 0.55 vs. 0.38, p &lt; 0.01) and greater hyperinflation (RV 124 vs. 99, p &lt; 0.001) were observed in patients with obstructed airways. Impulse oscillometry reactance markers (X5, Fres, AX) significantly differentiated obstructive from restrictive pathophysiology (p &lt; 0.02). In the obstructive group, sRaw correlated with R5 (p = 0.01) and R5-20 (r = 0.58, p &lt; 0.001), while AX correlated with RV (r = 0.59, p &lt; 0.001). Restrictive patients revealed negative correlations between AX and static volumes (RV, TLC, RV\/TLC; all p &lt; 0.05). DLCO was higher in obstructive patients (75 vs. 62, p = 0.01). Conclusions: Our study demonstrates that body plethysmography and impulse oscillometry provide complementary information on respiratory mechanics and that the results obtained with the two methods correlate significantly, especially in obstructive diseases.<\/jats:p>","DOI":"10.3390\/diagnostics15233055","type":"journal-article","created":{"date-parts":[[2025,12,2]],"date-time":"2025-12-02T15:31:46Z","timestamp":1764689506000},"page":"3055","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Correlation Between Body Plethysmography and Impulse Oscillometry Across Obstructive and Restrictive Lung Diseases: Evidence from an Adult Pilot Study Cohort"],"prefix":"10.3390","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7785-0121","authenticated-orcid":false,"given":"Eugenia Corina","family":"Budin","sequence":"first","affiliation":[{"name":"Pathophysiology Department, George Emil Palade University of Medicine, Pharmacy, Science and Technology of T\u00e2rgu Mure\u0219, 540142 T\u00e2rgu Mure\u0219, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ioan","family":"Vladimir","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, George Emil Palade University of Medicine, Pharmacy, Science and Technology of T\u00e2rgu Mure\u0219, 540142 T\u00e2rgu Mure\u0219, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0226-1733","authenticated-orcid":false,"given":"Ruxandra Mioara","family":"R\u00e2jnoveanu","sequence":"additional","affiliation":[{"name":"Palliative Medicine Department, Iuliu Ha\u021bieganu University of Medicine and Pharmacy, 400371 Cluj-Napoca, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-0882-870X","authenticated-orcid":false,"given":"Drago\u0219","family":"Hu\u021banu","sequence":"additional","affiliation":[{"name":"Pulmonology Department, George Emil Palade University of Medicine, Pharmacy, Science and Technology of T\u00e2rgu Mures, 540139 T\u00e2rgu Mures, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-1695-6990","authenticated-orcid":false,"given":"Mara Andreea","family":"Vultur","sequence":"additional","affiliation":[{"name":"Pulmonology Department, George Emil Palade University of Medicine, Pharmacy, Science and Technology of T\u00e2rgu Mures, 540139 T\u00e2rgu Mures, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-9439-0590","authenticated-orcid":false,"given":"Corina","family":"M\u0103rginean","sequence":"additional","affiliation":[{"name":"Oncology and Palliative Care Department, George Emil Palade University of Medicine, Pharmacy, Science and Technology of T\u00e2rgu Mure\u0219, 540139 T\u00e2rgu Mure\u0219, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-7066-7424","authenticated-orcid":false,"given":"Sofia Teodora","family":"Muntean","sequence":"additional","affiliation":[{"name":"Pathophysiology Department, George Emil Palade University of Medicine, Pharmacy, Science and Technology of T\u00e2rgu Mure\u0219, 540142 T\u00e2rgu Mure\u0219, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-3558-2856","authenticated-orcid":false,"given":"Edith Simona","family":"Iano\u0219i","sequence":"additional","affiliation":[{"name":"Pulmonology Department, George Emil Palade University of Medicine, Pharmacy, Science and Technology of T\u00e2rgu Mures, 540139 T\u00e2rgu Mures, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-1990-6767","authenticated-orcid":false,"given":"Gabriela","family":"Jimborean","sequence":"additional","affiliation":[{"name":"Pulmonology Department, George Emil Palade University of Medicine, Pharmacy, Science and Technology of T\u00e2rgu Mures, 540139 T\u00e2rgu Mures, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0590-1716","authenticated-orcid":false,"given":"Ovidiu Simion","family":"Cotoi","sequence":"additional","affiliation":[{"name":"Pathophysiology Department, George Emil Palade University of Medicine, Pharmacy, Science and Technology of T\u00e2rgu Mure\u0219, 540142 T\u00e2rgu Mure\u0219, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,11,29]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1016\/j.rmed.2011.02.006","article-title":"Body plethysmography\u2014Its principles and clinical use","volume":"105","author":"Sorichter","year":"2011","journal-title":"Respir. 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