{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T04:38:56Z","timestamp":1787027936889,"version":"build-2736575974"},"reference-count":37,"publisher":"MDPI AG","issue":"24","license":[{"start":{"date-parts":[[2025,12,7]],"date-time":"2025-12-07T00:00:00Z","timestamp":1765065600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"National Research Foundation of Korea (NRF) grant funded by the Korea government","award":["RS-2025-16065320"],"award-info":[{"award-number":["RS-2025-16065320"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostics"],"abstract":"<jats:p>Background: Precise localization of the mental foramen (MF) is essential to avoid mental nerve injury during implant placement, osteotomy, periapical surgery, and regional anesthesia. However, MF morphology and canal orientation show population-specific variability, and comprehensive morphometric data combining cadaveric dissection and CBCT analysis remain limited in Koreans. This study aimed to provide clinically applicable MF reference values for Korean adults. Methods: Thirty-two hemimandibles from 16 dentate Korean cadavers were examined through direct anatomical dissection. MF position relative to teeth, shape, vertical and horizontal diameters, and distances to the gingival margin, inferior border, and mandibular midline were measured. CBCT imaging of 12 hemimandibles was used to assess the internal trajectory and opening direction of the mental canal. Results: The MF was most frequently located below the second premolar (75%), followed by the P2\u2013M1 region (15.6%). Round foramina (62.5%) were more common than oval forms. Mean distances from the MF to the gingival margin, inferior border, and midline were 16.6 mm, 15.5 mm, and 26.5 mm, respectively. The mean horizontal diameter of the MF was 3.0 mm, and the mean vertical diameter was 2.2 mm. CBCT analysis revealed two emergence patterns\u2014posterolateral (50%) and lateral (50%). Conclusions: This study identified the positional characteristics, diameters, and canal emergence patterns of the MF in a cadaveric sample using dissection and CBCT. The findings regarding MF location, dimensions, and the opening direction of the mental canal provide practical anatomical information that may support safer implant placement, mental nerve blocks, and anterior mandibular surgery.<\/jats:p>","DOI":"10.3390\/diagnostics15243109","type":"journal-article","created":{"date-parts":[[2025,12,8]],"date-time":"2025-12-08T09:17:36Z","timestamp":1765185456000},"page":"3109","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Anatomical and CBCT-Based Evaluation of the Mental Foramen in Korean Adults: Clinical Implications for Implant Surgery and Mental Nerve Block"],"prefix":"10.3390","volume":"15","author":[{"given":"Yong-Ho","family":"Kim","sequence":"first","affiliation":[{"name":"Department of Anatomy, Daegu Catholic University School of Medicine, Daegu 42472, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1482-1657","authenticated-orcid":false,"given":"Mi-Sun","family":"Hur","sequence":"additional","affiliation":[{"name":"Department of Anatomy, Daegu Catholic University School of Medicine, Daegu 42472, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,12,7]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"709","DOI":"10.5603\/FM.a2017.0042","article-title":"The position of the mental foramen in dentate and edentulous mandibles: Clinical and surgical relevance","volume":"76","author":"Charalampakis","year":"2017","journal-title":"Folia Morphol."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1097\/SAP.0000000000004185","article-title":"Positioning of the Inferior Alveolar Nerve and Surgical Implications: A Study on Thai Mandibles","volume":"94","author":"Charoenvicha","year":"2025","journal-title":"Ann. Plast. Surg."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1016\/S1079-2104(98)90074-9","article-title":"Position of the mental foramen in a North American, white population","volume":"85","author":"Moiseiwitsch","year":"1998","journal-title":"Oral Surg. Oral Med. Oral Pathol. Oral Radiol. Endod."},{"key":"ref_4","unstructured":"Standring, S. (2020). Gray\u2019s Anatomy: The Anatomical Basis of Clinical Practice, Elsevier. [42nd ed.]."},{"key":"ref_5","unstructured":"Betz, D., and Fane, K. (2023). Mental Nerve Block. StatPearls [Internet], StatPearls Publishing."},{"key":"ref_6","unstructured":"Nguyen, J.D., and Duong, H. (2025). Anatomy, Head and Neck, Mental Nerve. StatPearls [Internet], StatPearls Publishing."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"1933","DOI":"10.1902\/jop.2006.060197","article-title":"The mental foramen and nerve: Clinical and anatomical factors related to dental implant placement\u2014A literature review","volume":"77","author":"Greenstein","year":"2006","journal-title":"J. Periodontol."},{"key":"ref_8","first-page":"8897275","article-title":"Evaluation of mental foramen with cone beam computed tomography: A systematic review of literature","volume":"2021","author":"Berry","year":"2021","journal-title":"Radiol. Res. Pract."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"682","DOI":"10.1016\/0030-4220(76)90325-X","article-title":"Roentgenologic study of the mental foramen","volume":"41","author":"Fishel","year":"1976","journal-title":"Oral Surg. Oral Med. Oral Pathol."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1159\/000146182","article-title":"A clinical and anatomical study of the location of the mental foramen in adult Chinese mandibles","volume":"126","author":"Wang","year":"1986","journal-title":"Acta Anat."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"171","DOI":"10.2334\/josnusd.45.171","article-title":"The location of the mental foramen in a selected Malay population","volume":"45","author":"Ngeow","year":"2003","journal-title":"J. Oral Sci."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"1061","DOI":"10.1902\/jop.2004.75.8.1061","article-title":"Morphometric analysis of implant-related anatomy in Caucasian skulls","volume":"75","author":"Neiva","year":"2004","journal-title":"J. Periodontol."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1097\/01.id.0000243319.66845.15","article-title":"Position of the mental foramen in a Korean population: A clinical and radiographic study","volume":"15","author":"Kim","year":"2006","journal-title":"Implant Dent."},{"key":"ref_14","first-page":"981","article-title":"The mental foramen in dentate and edentulous Brazilian mandibles","volume":"26","author":"Amorim","year":"2008","journal-title":"Int. J. Morphol."},{"key":"ref_15","first-page":"117","article-title":"Location of mental foramen in a selected Iranian population: A CBCT assessment","volume":"10","author":"Khojastepour","year":"2015","journal-title":"Iran Endod. J."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"1133","DOI":"10.1007\/s00276-018-2043-z","article-title":"Assessment of morphological and anatomical characteristics of the mental foramen using cone beam computed tomography","volume":"40","author":"Goyushov","year":"2018","journal-title":"Surg. Radiol. Anat."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1186\/s42269-020-00364-2","article-title":"Position and dimensions of the mental foramen and presence of the anterior loop in the Egyptian population: A retrospective CBCT study","volume":"44","author":"Shalash","year":"2020","journal-title":"Bull. Natl. Res. Cent."},{"key":"ref_18","doi-asserted-by":"crossref","unstructured":"Ahmed, A.A., Ahmed, R.M., Jamleh, A., and Spagnuolo, G. (2021). Morphometric Analysis of the Mandibular Canal, Anterior Loop, and Mental Foramen: A Cone-Beam Computed Tomography Evaluation. Int. J. Environ. Res. Public Health, 18.","DOI":"10.3390\/ijerph18073365"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1016\/j.sdentj.2022.04.001","article-title":"Assessment of the position and level of the mental nerve for placement of implants using cone-beam computed tomography and panoramic radiograph in the Saudi population","volume":"34","author":"AlQahtani","year":"2022","journal-title":"Saudi Dent. J."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"e70081","DOI":"10.1002\/cre2.70081","article-title":"A comprehensive analysis of the radiographic characteristics and bilateral symmetry of the mental foramen","volume":"11","author":"Algabri","year":"2025","journal-title":"Clin. Exp. Dent. Res."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1007\/s00276-008-0343-4","article-title":"Topography and location of the depressor anguli oris muscle with reference to the mental foramen","volume":"30","author":"Hur","year":"2008","journal-title":"Surg. Radiol. Anat."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1097\/00001665-200501000-00004","article-title":"Vulnerability of the inferior alveolar nerve and mental nerve during genioplasty: An anatomic study","volume":"16","author":"Hwang","year":"2005","journal-title":"J. Craniofac. Surg."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"75","DOI":"10.5115\/acb.2015.48.1.75","article-title":"Morphological assessment of the anterior loop of the mandibular canal in Koreans","volume":"48","author":"Yu","year":"2015","journal-title":"Anat. Cell Biol."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"2288","DOI":"10.1016\/j.joms.2007.06.658","article-title":"Branching patterns and intraosseous course of the mental nerve","volume":"65","author":"Hu","year":"2007","journal-title":"J. Oral Maxillofac. Surg."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"127","DOI":"10.5051\/jpis.2019.49.2.127","article-title":"Prognosis in case of nerve disturbance after mandibular implant surgery in relation to computed tomography findings and symptoms","volume":"49","author":"Na","year":"2019","journal-title":"J. Periodontal Implant Sci."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"125","DOI":"10.4103\/ccd.ccd_624_20","article-title":"Assessment of implant-related anatomical landmarks in the mandibular interforaminal region in an Iranian population using cone-beam computed tomography","volume":"13","author":"Nikkerdar","year":"2022","journal-title":"Contemp. Clin. Dent."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"9","DOI":"10.7181\/acfs.2016.17.1.9","article-title":"Anthropometric analysis of facial foramina in a Korean population: A three-dimensional computed tomographic study","volume":"17","author":"Lim","year":"2016","journal-title":"Arch. Craniofac. Surg."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"5821048","DOI":"10.1155\/2016\/5821048","article-title":"CBCT assessment of mental foramen position relative to anatomical landmarks","volume":"2016","author":"Sheikhi","year":"2016","journal-title":"Int. J. Dent."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"20180252","DOI":"10.1259\/dmfr.20180252","article-title":"Is ultrasonography sufficient for evaluation of the mental foramen?","volume":"48","year":"2019","journal-title":"Dentomaxillofac. Radiol."},{"key":"ref_30","doi-asserted-by":"crossref","unstructured":"Cimen, T., Saka, Y.Y., Ataman-Duruel, E.T., Duruel, O., G\u00fcney Yilmaz, H., and T\u00f6z\u00fcm, T.F. (2025). Evaluation of symphysis donor site quan tity by cone-beam computed tomography and its relation to anterior loop of mental foramen: An observational study. BMC Oral Health, 25.","DOI":"10.1186\/s12903-025-06242-5"},{"key":"ref_31","first-page":"e58519","article-title":"Evaluating the anterior loop of the mental nerve using cone beam CT Scans in the Jordanian population","volume":"16","author":"Ersheidat","year":"2024","journal-title":"Cureus"},{"key":"ref_32","first-page":"231","article-title":"Anterior Loop of the Mental Foramen in a Turkish Subpopulation with Dentate Patients: A Cone Beam Computed Tomography Study","volume":"5","author":"Demir","year":"2015","journal-title":"M\u00dcSBED"},{"key":"ref_33","first-page":"e239","article-title":"A retrospective radiographic evaluation of the anterior loop of the mental nerve: Comparison between panoramic radiography and cone beam computerized tomography","volume":"20","year":"2015","journal-title":"Med. Oral Patol. Oral Cir. Bucal"},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1007\/s12663-019-01249-2","article-title":"Evaluation of the dimensions of the anterior loop of the mental nerve in CBCT: A radiographic analysis","volume":"19","author":"Gupta","year":"2020","journal-title":"J. Maxillofac. Oral Surg."},{"key":"ref_35","first-page":"e30687","article-title":"Mental nerve anterior loop detection in panoramic and cone beam computed tomography radiograph for safe dental implant placement","volume":"14","author":"Othman","year":"2022","journal-title":"Cureus"},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1111\/cid.12609","article-title":"Prevalence and measurement of anterior loop of the mandibular canal using CBCT: A cross-sectional study","volume":"20","author":"Pc","year":"2018","journal-title":"Clin. Implant Dent. Relat. Res."},{"key":"ref_37","first-page":"e55600","article-title":"Assessment of the anterior loop and pattern of entry of mental nerve into the mental foramen: A radiographic study of panoramic images","volume":"16","author":"Krishnan","year":"2024","journal-title":"Cureus"}],"container-title":["Diagnostics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2075-4418\/15\/24\/3109\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,8]],"date-time":"2025-12-08T09:31:02Z","timestamp":1765186262000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2075-4418\/15\/24\/3109"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12,7]]},"references-count":37,"journal-issue":{"issue":"24","published-online":{"date-parts":[[2025,12]]}},"alternative-id":["diagnostics15243109"],"URL":"https:\/\/doi.org\/10.3390\/diagnostics15243109","relation":{},"ISSN":["2075-4418"],"issn-type":[{"value":"2075-4418","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,12,7]]}}}