{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,9]],"date-time":"2025-12-09T16:09:39Z","timestamp":1765296579850,"version":"3.46.0"},"reference-count":3,"publisher":"MDPI AG","issue":"24","license":[{"start":{"date-parts":[[2025,12,9]],"date-time":"2025-12-09T00:00:00Z","timestamp":1765238400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostics"],"abstract":"<jats:p>We report a case of a patient admitted to our coronary intensive care unit with chest pain and elevated cardiac troponin. Coronary angiography showed no obstructive coronary artery disease. The patient had a history of chronic rhinosinusitis and nasal polyps, treated with dupilumab. Laboratory tests revealed marked hypereosinophilia, prompting a cardiac MRI, which showed findings consistent with eosinophilic myocarditis. This diagnosis was later confirmed by endomyocardial biopsy. This case highlights the importance of differential diagnosis in cases of myocardial injury (characterized by increased cardiac troponin) and underscores the value of CMR as the most accurate non-invasive technique for detecting myocarditis.<\/jats:p>","DOI":"10.3390\/diagnostics15243136","type":"journal-article","created":{"date-parts":[[2025,12,9]],"date-time":"2025-12-09T15:50:02Z","timestamp":1765295402000},"page":"3136","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["A Particular Case of Myocardial Injury"],"prefix":"10.3390","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-4015-3503","authenticated-orcid":false,"given":"Dario","family":"Catapano","sequence":"first","affiliation":[{"name":"Cardiology Unit, Department of Translational Medical Sciences, University of Campania \u201cLuigi Vanvitelli\u201d, 80131 Naples, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonia","family":"Ascrizzi","sequence":"additional","affiliation":[{"name":"Cardiology Unit, Department of Translational Medical Sciences, University of Campania \u201cLuigi Vanvitelli\u201d, 80131 Naples, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-5669-574X","authenticated-orcid":false,"given":"Luigi","family":"Falco","sequence":"additional","affiliation":[{"name":"Cardiology Unit, Department of Translational Medical Sciences, University of Campania \u201cLuigi Vanvitelli\u201d, 80131 Naples, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7153-4040","authenticated-orcid":false,"given":"Santo","family":"Dellegrottaglie","sequence":"additional","affiliation":[{"name":"Advanced Cardiovascular Imaging Unit, Clinica Villa dei Fiori, 80011 Acerra, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4030-1126","authenticated-orcid":false,"given":"Alessandra","family":"Scatteia","sequence":"additional","affiliation":[{"name":"Advanced Cardiovascular Imaging Unit, Clinica Villa dei Fiori, 80011 Acerra, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesco Saverio","family":"Loffredo","sequence":"additional","affiliation":[{"name":"Cardiology Unit, Department of Translational Medical Sciences, University of Campania \u201cLuigi Vanvitelli\u201d, 80131 Naples, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4738-8642","authenticated-orcid":false,"given":"Enrica","family":"Pezzullo","sequence":"additional","affiliation":[{"name":"Cardiology Unit, Department of Translational Medical Sciences, University of Campania \u201cLuigi Vanvitelli\u201d, 80131 Naples, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rita","family":"Gravino","sequence":"additional","affiliation":[{"name":"Department of Cardiology, AORN dei Colli Monaldi Hospital, 80131 Naples, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3590-6983","authenticated-orcid":false,"given":"Paolo","family":"Golino","sequence":"additional","affiliation":[{"name":"Cardiology Unit, Department of Translational Medical Sciences, University of Campania \u201cLuigi Vanvitelli\u201d, 80131 Naples, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emilio","family":"di Lorenzo","sequence":"additional","affiliation":[{"name":"Department of Cardiology, AORN dei Colli Monaldi Hospital, 80131 Naples, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6781-7424","authenticated-orcid":false,"given":"Daniele","family":"Masarone","sequence":"additional","affiliation":[{"name":"Department of Cardiology, AORN dei Colli Monaldi Hospital, 80131 Naples, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2025,12,9]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"713","DOI":"10.1080\/17476348.2022.2090342","article-title":"Dupilumab-induced hypereosinophilia: Review of the literature and algorithm proposal for clinical management","volume":"16","author":"Caminati","year":"2022","journal-title":"Expert. Rev. Respir. Med."},{"key":"ref_2","first-page":"ehaf192","article-title":"ESC Scientific Document Group. 2025 ESC Guidelines for the management of myocarditis and pericarditis","volume":"29","author":"Collini","year":"2025","journal-title":"Eur. Heart J."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1186\/s12968-023-00979-0","article-title":"Cardiac magnetic resonance in histologically proven eosinophilic myocarditis","volume":"25","author":"Nordenswan","year":"2023","journal-title":"J. Cardiovasc. Magn. 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