{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T04:55:39Z","timestamp":1784868939081,"version":"3.55.0"},"reference-count":81,"publisher":"MDPI AG","issue":"24","license":[{"start":{"date-parts":[[2025,12,15]],"date-time":"2025-12-15T00:00:00Z","timestamp":1765756800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"University of Medicine and Pharmacy Carol Davila"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostics"],"abstract":"<jats:p>Background: Liver cirrhosis is a chronic systemic disease with a prevalence of 1.3% worldwide. Malnutrition refers to an imbalance of essential nutrients or altered utilization, with a prevalence ranging from 5 to 92%. The aim of this study is to assess the quality of life of cirrhotic patients and to investigate the incidence of malnutrition, thereby enabling the identification of high-risk groups by evaluating commonly used nutritional assessment tools in everyday clinical practice and identifying discrepancies between objective and subjective measures in cirrhotic patients. Methods: This is a single-center prospective study including patients diagnosed with liver cirrhosis from a tertiary center. Results: We included 53 patients, 81.13% (n = 43) of whom were men, with a mean age of 62.36 \u00b1 9.28. Most patients had hypoalbuminemia, vitamin D deficiency, and low levels of cholesterol, triglycerides, and magnesium. 64.15% (n = 34) had malnutrition according to the RFH-NPT test, while the SGA questionnaire revealed a high predominance of the A class. Higher mean MELD, MELD-Na, and MELD 3.0 scores were associated with higher RFH-NPT and SGA scores. The CLDQ presented lower mean values for disease progression. Conclusions: This study is a real-world evaluation of patients with liver cirrhosis referred to a tertiary center, revealing a low quality of life of the patients and a high prevalence of malnutrition.<\/jats:p>","DOI":"10.3390\/diagnostics15243206","type":"journal-article","created":{"date-parts":[[2025,12,15]],"date-time":"2025-12-15T13:32:37Z","timestamp":1765805557000},"page":"3206","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Real-Life Challenges in Assessing Nutritional Status and Quality of Life in Patients with Cirrhosis"],"prefix":"10.3390","volume":"15","author":[{"given":"Ioana","family":"Parola","sequence":"first","affiliation":[{"name":"Department of Gastroenterology, \u201cCarol Davila\u201d University of Medicine and Pharmacy, 020021 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-1894-4088","authenticated-orcid":false,"given":"Ilinca","family":"Savulescu-Fiedler","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, \u201cCarol Davila\u201d University of Medicine and Pharmacy, 050474 Bucharest, Romania"},{"name":"Department of Internal Medicine, Coltea Clinical Hospital, 030167 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8787-3829","authenticated-orcid":false,"given":"Sandica","family":"Bucurica","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, \u201cCarol Davila\u201d University of Medicine and Pharmacy, 020021 Bucharest, Romania"},{"name":"Department of Gastroenterology, \u201cDr. Carol Davila\u201d Central Military Emergency University Hospital, 010825 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9284-597X","authenticated-orcid":false,"given":"Ionela","family":"Maniu","sequence":"additional","affiliation":[{"name":"Department of Mathematics and Informatics, Faculty of Sciences, Lucian Blaga University Sibiu, 550012 Sibiu, Romania"},{"name":"Research Team, Pediatric Clinical Hospital Sibiu, 550166 Sibiu, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bianca","family":"Cheaib","sequence":"additional","affiliation":[{"name":"Department of Medical Oncology, Gustave Roussy Institute, 94805 Villejuif Cedex, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5826-0815","authenticated-orcid":false,"given":"Mariana","family":"Jinga","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, \u201cCarol Davila\u201d University of Medicine and Pharmacy, 020021 Bucharest, Romania"},{"name":"Department of Gastroenterology, \u201cDr. Carol Davila\u201d Central Military Emergency University Hospital, 010825 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,12,15]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"718","DOI":"10.1016\/j.jhep.2018.05.011","article-title":"Burden of liver disease in Europe: Epidemiology and analysis of risk factors to identify prevention policies","volume":"69","author":"Pimpin","year":"2018","journal-title":"J. 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