{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,11]],"date-time":"2026-10-11T00:53:35Z","timestamp":1791680015461,"version":"4.3.4"},"reference-count":18,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2025,12,20]],"date-time":"2025-12-20T00:00:00Z","timestamp":1766188800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Jinshan"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostics"],"abstract":"<jats:p>Background and Aims: Colon capsule endoscopy (CCE) provides a non-invasive alternative to traditional colonoscopy. This study evaluated the feasibility, safety, diagnostic yield (DY), and patient satisfaction of the OMOM CC100 CCE system, with special focus on fully remote (n = 30) and partially remote (n = 89) administration across four centres to advance decentralised models. Methods: This prospective, investigator-initiated, international multicentre feasibility study enrolled 119 patients aged 18\u201375 years at centres in Denmark, Sweden, Portugal, and Poland from July 2024 to May 2025. Indications included rectal bleeding, iron-deficiency anaemia, a positive faecal immunochemical test, changes in bowel habit, suspected inflammatory bowel disease (IBD), post-polypectomy or colorectal cancer (CRC) surgery surveillance, and a family history of CRC. The OMOM CC100 capsule was employed with a standardised bowel preparation regimen. Administration was fully remote in Denmark using the IntelliGI\u2122 platform and partially remote (clinic ingestion, home completion) at the other sites. Primary outcomes encompassed procedure feasibility, completion rate (capsule excretion or anal verge visualisation), bowel cleanliness (Leighton-Rex scale \u2265 3), diagnostic yield, and patient satisfaction. Secondary measures included transit times, adverse events, and technical failures. Results: Median age was 55.7 years (65 males, 54 females). Overall completion rate was 79%, varying by centre: Sweden (90%), Portugal (81%), Denmark (80%), and Poland (63%). Adequate bowel cleanliness was achieved in 71% of cases. Diagnostic findings included polyps (25 patients), angioectasia (20), diverticulosis (17), and mucosal inflammation (17); 42% were normal. Fully remote administration yielded 80% completion and 89.7% satisfaction. No serious adverse events occurred; overall satisfaction was 81%, with 87% preferring home-based procedures. Conclusions: The OMOM CC100 CCE system is feasible, safe, with DY comparable to established systems. IntelliGI\u2122-enabled remote administration promotes decentralised care, enhancing accessibility.<\/jats:p>","DOI":"10.3390\/diagnostics16010020","type":"journal-article","created":{"date-parts":[[2025,12,22]],"date-time":"2025-12-22T08:35:27Z","timestamp":1766392527000},"page":"20","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Prospective, Multicentre Feasibility Study of Remote Colon Capsule Endoscopy Using the OMOM CC100 System"],"prefix":"10.3390","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-0781-7484","authenticated-orcid":false,"given":"Alexandra","family":"Agache","sequence":"first","affiliation":[{"name":"Department of Clinical Research, University of Southern Denmark (SDU), 5000 Odense C, Denmark"},{"name":"Department of Surgery, Odense University Hospital (OUH), 5000 Odense C, Denmark"},{"name":"Department of General Surgery, University of Medicine and Pharmacy \u2018Carol Davila\u2019, 050474 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9314-9239","authenticated-orcid":false,"given":"Ervin","family":"Toth","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Sk\u00e5ne University Hospital, 205 02 Malm\u00f6, Sweden"},{"name":"Department of Clinical Sciences Malm\u00f6, Lund University, 22100 Malm\u00f6, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1113-195X","authenticated-orcid":false,"given":"Niels","family":"Qvist","sequence":"additional","affiliation":[{"name":"Department of Surgery, Odense University Hospital (OUH), 5000 Odense C, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0340-0830","authenticated-orcid":false,"given":"Miguel","family":"Mascarenhas","sequence":"additional","affiliation":[{"name":"Gastroenterology, Centro Hospitalar S\u00e3o Jo\u00e3o, 4200-319 Porto, Portugal"},{"name":"WGO Gastroenterology and Hepatology Training Center, 4200-437 Porto, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wojciech","family":"Marlicz","sequence":"additional","affiliation":[{"name":"The Centre for Digestive Diseases, Endoklinika sp. z o.o., Kurza Stopka 3,4, 70-535 Szczecin, Poland"},{"name":"Department of Gastroenterology, Pomeranian Medical University, Unii Lubelskiej 1, 70-204 Szczecin, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7643-2350","authenticated-orcid":false,"given":"Benedicte","family":"Schelde-Olesen","sequence":"additional","affiliation":[{"name":"Department of Clinical Research, University of Southern Denmark (SDU), 5000 Odense C, Denmark"},{"name":"Department of Surgery, Odense University Hospital (OUH), 5000 Odense C, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miguel","family":"Mascarenhas-Saraiva","sequence":"additional","affiliation":[{"name":"ManopH, Digestive Endoscopy & Motility Lab., 4000-432 Porto, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-4285-612X","authenticated-orcid":false,"given":"Maria","family":"Marlicz","sequence":"additional","affiliation":[{"name":"The Centre for Digestive Diseases, Endoklinika sp. z o.o., Kurza Stopka 3,4, 70-535 Szczecin, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1014-4369","authenticated-orcid":false,"given":"Gabriele Wurm","family":"Johansson","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Sk\u00e5ne University Hospital, 205 02 Malm\u00f6, Sweden"},{"name":"Department of Clinical Sciences Malm\u00f6, Lund University, 22100 Malm\u00f6, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Artur","family":"Nemeth","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Sk\u00e5ne University Hospital, 205 02 Malm\u00f6, Sweden"},{"name":"Department of Clinical Sciences Malm\u00f6, Lund University, 22100 Malm\u00f6, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2248-489X","authenticated-orcid":false,"given":"Anastasios","family":"Koulaouzidis","sequence":"additional","affiliation":[{"name":"Department of Clinical Research, University of Southern Denmark (SDU), 5000 Odense C, Denmark"},{"name":"Department of Surgery, Odense University Hospital (OUH), 5000 Odense C, Denmark"},{"name":"Department of Gastroenterology, Pomeranian Medical University, Unii Lubelskiej 1, 70-204 Szczecin, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,12,20]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"173","DOI":"10.3390\/gidisord3040018","article-title":"Colorectal Cancer Screening: Have We Addressed Concerns and Needs of the Target Population?","volume":"3","author":"Tran","year":"2021","journal-title":"Gastrointest. Disord."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"e258867","DOI":"10.1001\/jamanetworkopen.2025.8867","article-title":"Comorbidities, Socioeconomic Status, and Colorectal Cancer Diagnostic Route","volume":"8","author":"Pennisi","year":"2025","journal-title":"JAMA Netw. Open"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"a26415952","DOI":"10.1055\/a-2641-5952","article-title":"Colon capsule endoscopy today: Brief overview of leading UK and Danish initiatives","volume":"13","author":"Justsen","year":"2025","journal-title":"Endosc. Int. Open"},{"key":"ref_4","doi-asserted-by":"crossref","unstructured":"Deding, U., Cortegoso Valdivia, P., Koulaouzidis, A., Baatrup, G., Toth, E., Spada, C., Fern\u00e1ndez-Uri\u00e9n, I., Pennazio, M., and Bj\u00f8rsum-Meyer, T. (2021). Patient-Reported Outcomes and Preferences for Colon Capsule Endoscopy and Colonoscopy: A Systematic Review with Meta-Analysis. 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