{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T05:25:44Z","timestamp":1788931544698,"version":"build-2803163510"},"reference-count":45,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001459","name":"Ministry of Education","doi-asserted-by":"publisher","award":["VEGA 1\/0700\/23"],"award-info":[{"award-number":["VEGA 1\/0700\/23"]}],"id":[{"id":"10.13039\/501100001459","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostics"],"abstract":"<jats:p>Background\/Objectives: Cardiovascular (CV) diseases remain the leading cause of morbidity and mortality across Europe. Despite substantial progress in prevention, diagnostics, and therapeutics, outpatient cardiology care continues to face systemic challenges, including limited consultation time, workforce constraints, and incomplete clinical information at the point of care. The primary objective of this study is threefold. First, to evaluate whether AI-enhanced telemedicine improves clinical control of hypertension, dyslipidemia, and heart failure compared to standard ambulatory care. Second, to assess the impact on physician workflow efficiency and documentation burden through AI-assisted clinical documentation. Third, to determine patient satisfaction and safety profiles of integrated telemedicine\u2013AI systems. Clinical control will be measured by a composite endpoint of disease-specific targets assessed at the 12-month follow-up visit. Methods: The TeleAI-CVD Concept Study aims to evaluate the integration of telemedicine and artificial intelligence (AI) to enhance the efficiency, quality, and individualization of cardiovascular disease management in the ambulatory setting. Within this framework, AI-driven tools will be employed to collect structured clinical histories and current symptomatology from patients prior to outpatient visits using digital questionnaires and conversational interfaces. Results: Obtained data, combined with telemonitoring metrics, laboratory parameters, and existing clinical records, will be synthesized to support clinical decision-making. Conclusions: This approach is expected to streamline consultations, increase diagnostic accuracy, and enable personalized, data-driven care through continuous evaluation of patient trajectories. The anticipated outcomes of the TeleAI-CVD study include the development of optimized, AI-assisted management protocols for cardiology patients, a reduction in unnecessary in-person visits through effective telemedicine-based follow-up, and accelerated attainment of therapeutic targets. Ultimately, this concept seeks to redefine the paradigm of outpatient cardiovascular care by embedding advanced digital technologies within routine clinical workflows.<\/jats:p>","DOI":"10.3390\/diagnostics16010145","type":"journal-article","created":{"date-parts":[[2026,1,2]],"date-time":"2026-01-02T09:18:56Z","timestamp":1767345536000},"page":"145","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Application of Telemedicine and Artificial Intelligence in Outpatient Cardiology Care: TeleAI-CVD Study (Design)"],"prefix":"10.3390","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9789-3305","authenticated-orcid":false,"given":"Stefan","family":"Toth","sequence":"first","affiliation":[{"name":"SLOVACRIN & MEDIPARK, Faculty of Medicine, Pavol Jozef Safarik University, Trieda SNP 1, 040 01 Kosice, Slovakia"},{"name":"Cardiology Outpatient Clinic, Kardiocomp s.r.o., Letna 45, 040 11 Kosice, Slovakia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marianna","family":"Barbierik Vachalcova","sequence":"additional","affiliation":[{"name":"School of Medicine, East Slovak Institute of Cardiovascular Diseases, Pavol Jozef Safarik University, Trieda SNP 1, 040 11 Kosice, Slovakia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kamil","family":"Barbierik","sequence":"additional","affiliation":[{"name":"SLOVACRIN & MEDIPARK, Faculty of Medicine, Pavol Jozef Safarik University, Trieda SNP 1, 040 01 Kosice, Slovakia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adriana","family":"Jarolimkova","sequence":"additional","affiliation":[{"name":"Cardiology Outpatient Clinic, Kardiocomp s.r.o., Letna 45, 040 11 Kosice, Slovakia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8811-025X","authenticated-orcid":false,"given":"Pavol","family":"Fulop","sequence":"additional","affiliation":[{"name":"School of Medicine, East Slovak Institute of Cardiovascular Diseases, Pavol Jozef Safarik University, Trieda SNP 1, 040 11 Kosice, Slovakia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariana","family":"Dvoroznakova","sequence":"additional","affiliation":[{"name":"School of Medicine, East Slovak Institute of Cardiovascular Diseases, Pavol Jozef Safarik University, Trieda SNP 1, 040 11 Kosice, Slovakia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dominik","family":"Pella","sequence":"additional","affiliation":[{"name":"School of Medicine, East Slovak Institute of Cardiovascular Diseases, Pavol Jozef Safarik University, Trieda SNP 1, 040 11 Kosice, Slovakia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6946-3765","authenticated-orcid":false,"given":"Tibor","family":"Poruban","sequence":"additional","affiliation":[{"name":"School of Medicine, East Slovak Institute of Cardiovascular Diseases, Pavol Jozef Safarik University, Trieda SNP 1, 040 11 Kosice, Slovakia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,1,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"3627","DOI":"10.1093\/eurheartj\/ehad195","article-title":"2023 Focused Update of the 2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure","volume":"44","author":"McDonagh","year":"2023","journal-title":"Eur. 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