{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T22:43:28Z","timestamp":1790721808318,"version":"4.1.0"},"reference-count":26,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2026,1,9]],"date-time":"2026-01-09T00:00:00Z","timestamp":1767916800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostics"],"abstract":"<jats:p>Background\/Objectives: The early and accurate identification of impacted teeth in the maxilla is critical for effective dental treatment planning. Traditional diagnostic methods relying on manual interpretation of radiographic images are often time-consuming and subject to variability. Methods: This study presents a deep learning-based approach for automated classification of impacted maxillary canines using panoramic radiographs. A comparative evaluation of four pre-trained convolutional neural network (CNN) architectures\u2014ResNet50, Xception, InceptionV3, and VGG16\u2014was conducted through transfer learning techniques. In this retrospective single-center study, the dataset comprised 694 annotated panoramic radiographs sourced from the archives of a university dental hospital, with a mildly imbalanced representation of impacted and non-impacted cases. Models were assessed using accuracy, precision, recall, specificity, and F1-score. Results: Among the tested architectures, VGG16 demonstrated superior performance, achieving an accuracy of 99.28% and an F1-score of 99.43%. Additionally, a prototype diagnostic interface was developed to demonstrate the potential for clinical application. Conclusions: The findings underscore the potential of deep learning models, particularly VGG16, in enhancing diagnostic workflows; however, further validation on diverse, multi-center datasets is required to confirm clinical generalizability.<\/jats:p>","DOI":"10.3390\/diagnostics16020219","type":"journal-article","created":{"date-parts":[[2026,1,9]],"date-time":"2026-01-09T16:03:16Z","timestamp":1767974596000},"page":"219","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Comparative Evaluation of Deep Learning Models for the Classification of Impacted Maxillary Canines on Panoramic Radiographs"],"prefix":"10.3390","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9840-4211","authenticated-orcid":false,"given":"Nazl\u0131","family":"Tokatl\u0131","sequence":"first","affiliation":[{"name":"Department of Computer Engineering, Faculty of Engineering and Natural Sciences, Istanbul Health and Technology University, 34275 Istanbul, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-6316-6072","authenticated-orcid":false,"given":"Buket","family":"Erdem","sequence":"additional","affiliation":[{"name":"Department of Orthodontics, Faculty of Dentistry, Istanbul Health and Technology University, 34275 Istanbul, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-8331-9493","authenticated-orcid":false,"given":"Mustafa","family":"\u00d6zcan","sequence":"additional","affiliation":[{"name":"Department of Orthodontics, Faculty of Dentistry, Istanbul Health and Technology University, 34275 Istanbul, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7859-2198","authenticated-orcid":false,"given":"Beg\u00fcm","family":"Turan Mavi\u015f","sequence":"additional","affiliation":[{"name":"Department of Orthodontics, Faculty of Dentistry, Marmara University, 34722 Istanbul, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4966-9779","authenticated-orcid":false,"given":"\u00c7a\u011fla","family":"\u015ear","sequence":"additional","affiliation":[{"name":"Department of Orthodontics, Faculty of Dentistry, Istanbul Health and Technology University, 34275 Istanbul, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2460-0724","authenticated-orcid":false,"given":"Fulya","family":"\u00d6zdemir","sequence":"additional","affiliation":[{"name":"Department of Orthodontics, Faculty of Dentistry, Istanbul Health and Technology University, 34275 Istanbul, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,1,9]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Becker, A. 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