{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,19]],"date-time":"2026-01-19T22:57:06Z","timestamp":1768863426664,"version":"3.49.0"},"reference-count":40,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2026,1,17]],"date-time":"2026-01-17T00:00:00Z","timestamp":1768608000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100005762","name":"National Taiwan University Hospital","doi-asserted-by":"publisher","award":["NTUH-112-O0010"],"award-info":[{"award-number":["NTUH-112-O0010"]}],"id":[{"id":"10.13039\/501100005762","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006245","name":"Ministry of Science and Technology","doi-asserted-by":"publisher","award":["MOST 111-2314-B-002-1330"],"award-info":[{"award-number":["MOST 111-2314-B-002-1330"]}],"id":[{"id":"10.13039\/501100006245","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004663","name":"National Science and Technology Council","doi-asserted-by":"publisher","award":["NSTC 112-2314-B-002-257"],"award-info":[{"award-number":["NSTC 112-2314-B-002-257"]}],"id":[{"id":"10.13039\/501100004663","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostics"],"abstract":"<jats:p>Background\/Objectives: Autosomal dominant polycystic kidney disease (ADPKD) is a major cause of end-stage kidney disease (ESKD), accounting for approximately 5\u201310% of patients receiving dialysis worldwide. The large and numerous cysts in the liver and kidneys cause abdominal distention and poor appetite. Previous studies showed that renal arterial embolization (RAE) reduces total kidney volume (TKV), increases appetite, and improves quality of life. This article aims to evaluate the efficacy of RAE in increasing psoas muscle (PM) and paraspinal muscle (PS) mass in patients with polycystic kidney disease. Methods: A retrospective study was conducted from May 2016 to December 2020. Thirty-five patients with PKD and ESKD who received RAE were enrolled. The clinical data, including age, sex, body weight, abdominal circumference, and laboratory results, including albumin, creatinine, estimated glomerular filtration rate, and dialysis vintage, were collected. TKV was calculated with the ellipsoid formula method, and muscle mass was measured with bilateral PM and PS areas at the third lumbar level. The associated clinical, laboratory, and imaging data were compared before and after RAE. Results: There were 19 females and 16 males with a mean age of 59.9 for the final analysis. There were significant changes between baseline and 3-month, 6-month, 12-month after RAE, such as a decrease in TKV (4684 \u00b1 3361 vs. 4079 \u00b1 3456, 3675 \u00b1 3401, 2459 \u00b1 1706 mL, all p &lt; 0.001), an increase in the PM area (12.6 \u00b1 5.8 vs. 13.3 \u00b1 5.7, 14.7 \u00b1 6.9, 14.3 \u00b1 7.1 cm2, all p &lt; 0.05), but no difference in body weight, body mass index, albumin, hemoglobin, creatinine, or estimated glomerular filtration rate. The increase in the PM and PS was more obvious in the sarcopenic group than in the non-sarcopenic group in the 12-month follow-up (p = 0.001 and 0.016 vs. p = 0.205 and 0.259). Conclusions: RAE effectively reduces TKV, increases PM and PS mass, and serves as a candidate to reverse muscle loss in patients with PKD.<\/jats:p>","DOI":"10.3390\/diagnostics16020302","type":"journal-article","created":{"date-parts":[[2026,1,19]],"date-time":"2026-01-19T09:57:02Z","timestamp":1768816622000},"page":"302","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Efficacy of Transcatheter Renal Arterial Embolization to Contract Renal Size and Increase Muscle Mass in Patients with Polycystic Kidney Disease"],"prefix":"10.3390","volume":"16","author":[{"given":"Che-Ming","family":"Lin","sequence":"first","affiliation":[{"name":"Department of Radiology, Shuang Ho Hospital, Taipei Medical University, New Taipei City\u00a0235, Taiwan"},{"name":"Department of Radiology, School of Medicine, College of Medicine, Taipei Medical University, Taipei 110301, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tai-Shuan","family":"Lai","sequence":"additional","affiliation":[{"name":"Departments of Internal Medicine, National Taiwan University Hospital, Taipei 100225, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ting-Wei","family":"Liao","sequence":"additional","affiliation":[{"name":"Department of Medical Imaging, National Taiwan University Hospital, Taipei 100225, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Trianingsih","sequence":"additional","affiliation":[{"name":"Department of Radiology, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada, Dr. Sardjito General Hospital, Yogyakarta 55284, Indonesia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ying-Hui","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Medical Imaging, National Taiwan University Hospital, Taipei 100225, Taiwan"},{"name":"Center of Minimal-Invasive Interventional Radiology, National Taiwan University Hospital, Taipei 100225, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chun-Jung","family":"Cheng","sequence":"additional","affiliation":[{"name":"Department of Medical Imaging, National Taiwan University Hospital, Taipei 100225, Taiwan"},{"name":"Center of Minimal-Invasive Interventional Radiology, National Taiwan University Hospital, Taipei 100225, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chih-Horng","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Medical Imaging, National Taiwan University Hospital, Taipei 100225, Taiwan"},{"name":"Center of Minimal-Invasive Interventional Radiology, National Taiwan University Hospital, Taipei 100225, Taiwan"},{"name":"Hepatitis Research Center, National Taiwan University Hospital, Taipei 100225, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2026,1,17]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1718","DOI":"10.1093\/ndt\/gfv133","article-title":"Sarcopenia in chronic kidney disease on conservative therapy: Prevalence and association with mortality","volume":"30","author":"Pereira","year":"2015","journal-title":"Nephrol. 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