{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,6]],"date-time":"2026-07-06T19:58:34Z","timestamp":1783367914229,"version":"3.54.6"},"reference-count":172,"publisher":"MDPI AG","issue":"8","license":[{"start":{"date-parts":[[2026,4,19]],"date-time":"2026-04-19T00:00:00Z","timestamp":1776556800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostics"],"abstract":"<jats:p>Background and Clinical Significance: Parry\u2013Romberg syndrome (PRS), also known as progressive hemifacial atrophy, is a rare disorder characterized by progressive unilateral hemifacial atrophy, with potential involvement of the cranial bones and the brain. Although neurological manifestations are frequently described, central nervous system involvement may be subclinical and detectable only through neuroimaging. Owing to its rarity and the lack of standardized diagnostic criteria, most available data derive from case reports and small case series. Case Presentation: We report the case of a 38-year-old female patient diagnosed with PRS (stage 2 according to the Guerrerosantos classification), with onset in childhood characterized by left parietal alopecia, followed by progressive left-sided hemifacial atrophy and a linear \u201cen coup de sabre\u201d lesion. Neurological examination was normal, with no history of seizures or focal deficits. Brain MRI revealed ipsilateral cutaneous, subcutaneous, muscular, and osseous atrophy, as well as atrophy of the left parotid and submandibular glands. Additionally, subcortical white matter lesions were identified in the left frontal lobe in the absence of hemispheric cerebral atrophy. Conclusions: This case highlights a significant radioclinical dissociation, demonstrating that central nervous system involvement may occur even in clinically stable and paucisymptomatic forms of PRS. This disease may be associated with subclinical intracranial abnormalities, underscoring the need for systematic neuroimaging evaluation even in the absence of neurological manifestations. Based on the available literature and the specific features of the present case, we propose a practical clinical framework and imaging algorithm to facilitate early diagnosis and to contribute to the standardization of the diagnostic approach in this rare disorder.<\/jats:p>","DOI":"10.3390\/diagnostics16081219","type":"journal-article","created":{"date-parts":[[2026,4,20]],"date-time":"2026-04-20T07:15:08Z","timestamp":1776669308000},"page":"1219","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Parry\u2013Romberg Syndrome: Radioclinical Dissociation in a Paucisymptomatic Form and a Proposed Diagnostic Framework"],"prefix":"10.3390","volume":"16","author":[{"given":"Cristian","family":"Turlea","sequence":"first","affiliation":[{"name":"Faculty of Medicine, Vasile Goldis Western University of Arad, 310025 Arad, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1441-1751","authenticated-orcid":false,"given":"Andrei I.","family":"Cucu","sequence":"additional","affiliation":[{"name":"Faculty of Medicine and Biological Sciences, Stefan cel Mare University of Suceava, 720229 Suceava, Romania"},{"name":"Emerald Medical Center, 700505 Iasi, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9112-7039","authenticated-orcid":false,"given":"Alexandru","family":"Carauleanu","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Grigore T. Popa University of Medicine and Pharmacy Iasi, 700115 Iasi, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7386-0859","authenticated-orcid":false,"given":"Roxana","family":"Covali","sequence":"additional","affiliation":[{"name":"Faculty of Medical Bioengineering, Grigore T. Popa University of Medicine and Pharmacy Iasi, 700115 Iasi, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Camelia","family":"Tamas","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Grigore T. Popa University of Medicine and Pharmacy Iasi, 700115 Iasi, Romania"},{"name":"Clinical Emergency Hospital St. Spiridon, 700111 Iasi, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mihnea A.","family":"Popa","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Grigore T. Popa University of Medicine and Pharmacy Iasi, 700115 Iasi, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Victor","family":"Constantinescu","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Grigore T. Popa University of Medicine and Pharmacy Iasi, 700115 Iasi, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anca P.","family":"Morosan","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Grigore T. Popa University of Medicine and Pharmacy Iasi, 700115 Iasi, Romania"},{"name":"Clinical Emergency Hospital St. Spiridon, 700111 Iasi, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2859-2066","authenticated-orcid":false,"given":"Elena","family":"Porumb-Andrese","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Grigore T. Popa University of Medicine and Pharmacy Iasi, 700115 Iasi, Romania"},{"name":"Clinical Emergency Hospital St. Spiridon, 700111 Iasi, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6853-1463","authenticated-orcid":false,"given":"Iulian","family":"Prutianu","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Grigore T. Popa University of Medicine and Pharmacy Iasi, 700115 Iasi, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2488-2154","authenticated-orcid":false,"given":"Claudia F.","family":"Costea","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Grigore T. Popa University of Medicine and Pharmacy Iasi, 700115 Iasi, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-2874-9227","authenticated-orcid":false,"given":"Amelian","family":"Bobu","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Grigore T. Popa University of Medicine and Pharmacy Iasi, 700115 Iasi, Romania"},{"name":"Clinical Emergency Hospital St. Spiridon, 700111 Iasi, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6505-1699","authenticated-orcid":false,"given":"Adriana","family":"Hristea","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Carol Davila University of Medicine and Pharmacy, 050474 Bucharest, Romania"},{"name":"National Institute for Infectious Diseases \u201cProf. Dr. Matei Bals\u201d, 021105 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4376-4874","authenticated-orcid":false,"given":"Alexandru","family":"Nemtoi","sequence":"additional","affiliation":[{"name":"Faculty of Medicine and Biological Sciences, Stefan cel Mare University of Suceava, 720229 Suceava, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,4,19]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1186\/s13023-015-0250-9","article-title":"Progressive Hemifacial Atrophy: A Review","volume":"10","author":"Tolkachjov","year":"2015","journal-title":"Orphanet J. Rare Dis."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1016\/j.jaad.2012.01.019","article-title":"A Review of Parry-Romberg Syndrome","volume":"67","author":"Abbas","year":"2012","journal-title":"J. Am. Acad. Dermatol."},{"key":"ref_3","doi-asserted-by":"crossref","unstructured":"Iyer, J., Hariharan, A., Cao, U.M.N., and Tran, S.D. (2021). Acquired Facial, Maxillofacial, and Oral Asymmetries\u2014A Review Highlighting Diagnosis and Management. Symmetry, 13.","DOI":"10.3390\/sym13091661"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1046\/j.1525-1470.1999.0le16.x","article-title":"Parry-Romberg Syndrome with Ipsilateral Cerebral Atrophy of Neonatal Onset","volume":"16","author":"Chang","year":"1999","journal-title":"Pediatr. Dermatol."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"104234","DOI":"10.1016\/j.ejmg.2021.104234","article-title":"A Unique Case of Progressive Hemifacial Microsomia or Parry-Romberg Syndrome Associated with Limb and Brain Anomalies with Normal Neurological Findings: A Review of the Literature","volume":"64","author":"Pattnaik","year":"2021","journal-title":"Eur. J. Med. Genet."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1159\/000314927","article-title":"Parry-Romberg Syndrome Associated with Localized Scleroderma","volume":"2","author":"Maletic","year":"2010","journal-title":"Case Rep. Neurol."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1136\/jnnp.70.4.524","article-title":"Neurology in Ancient Faces","volume":"70","author":"Appenzeller","year":"2001","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"key":"ref_8","unstructured":"Parry, C.H. (1825). Collections from the Unpublished Medical Writings of the Late Caleb Hillier Parry, Underwood."},{"key":"ref_9","unstructured":"Romberg, H.M. (1846). Krankheiten Des Nervensystems (IV: Trophoneurosen). Klinische Ergebnisse, Forrtner."},{"key":"ref_10","unstructured":"(2025). 12th Meeting International Society for the History of Medicine, Instituto de \u00c9tica Cl\u00ednica Francisco Vall\u00e9s."},{"key":"ref_11","unstructured":"Eulenberg, A. (1871). Hemiatrophia Facialis Progressiva. Lehrbuch der Funktionellen Nervenkrankheiten auf Physiologischer Basis, Verlag von August Hirschwald. (In German)."},{"key":"ref_12","doi-asserted-by":"crossref","unstructured":"Bergler-Czop, B., Lis-\u015awi\u0119ty, A., and Brzezi\u0144ska-Wcis\u0142o, L. (2009). Scleroderma Linearis: Hemiatrophia Faciei Progressiva (Parry-Romberg Syndrom) without Any Changes in CNS and Linear Scleroderma \u201cEn Coup de Sabre\u201d with CNS Tumor. BMC Neurol., 9.","DOI":"10.1186\/1471-2377-9-39"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"850","DOI":"10.3174\/ajnr.A7517","article-title":"Brain Abnormalities and Epilepsy in Patients with Parry-Romberg Syndrome","volume":"43","author":"Jain","year":"2022","journal-title":"AJNR Am. J. Neuroradiol."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"1915","DOI":"10.1212\/WNL.50.6.1915","article-title":"Progressive Facial Hemiatrophy: Abnormality of Intracranial Vasculature","volume":"50","author":"Woolfenden","year":"1998","journal-title":"Neurology"},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"929","DOI":"10.1111\/jpc.16143","article-title":"Hemi-Atrophy of the Face","volume":"59","author":"Selvam","year":"2023","journal-title":"J. Paediatr. Child. Health"},{"key":"ref_16","first-page":"e32287","article-title":"Parry Romberg Syndrome in a Young Ghanaian: A Case Report and a Literature Review","volume":"14","author":"Edzie","year":"2022","journal-title":"Cureus"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"1355","DOI":"10.3174\/ajnr.A4297","article-title":"Parry Romberg Syndrome: 7 Cases and Literature Review","volume":"36","author":"Wong","year":"2015","journal-title":"AJNR Am. J. Neuroradiol."},{"key":"ref_18","doi-asserted-by":"crossref","unstructured":"Long, L., Kang, Z., Chen, S., Cui, C., Men, X., and Qiu, W. (2020). A Case Report of Parry-Romberg Syndrome Misdiagnosed as Multiple Sclerosis. Front. Neurol., 11.","DOI":"10.3389\/fneur.2020.00797"},{"key":"ref_19","first-page":"227","article-title":"Ocular manifestations in progressive facial hemiatrophy (Parry-Romberg syndrome)","volume":"29","author":"Cernea","year":"1985","journal-title":"Rev. Chir. Oncol. Radiol. ORL Oftalmol. Stomatol. Ser. Oftalmol."},{"key":"ref_20","first-page":"299","article-title":"Progressive hemiatrophy of the face-Parry-Romberg syndrome","volume":"31","author":"Zolog","year":"1987","journal-title":"Rev. Chir. Oncol. Radiol. ORL Oftalmol. Stomatol. Ser. Oftalmol."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"209","DOI":"10.37897\/RJR.2016.4.7","article-title":"Parry Romberg Syndrome","volume":"25","author":"Cochino","year":"2016","journal-title":"Rom. J. Rheumatol."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"59","DOI":"10.37897\/RJN.2011.1.9","article-title":"Exacerbation of secondary trigeminal neuralgia due to osteomyelitis in a case of Romberg Facial Hemiatrophy","volume":"10","author":"Popovici","year":"2011","journal-title":"Rom. J. Neurol."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1007\/s00266-006-0215-4","article-title":"Classification and Treatment of Facial Tissue Atrophy in Parry-Romberg Disease","volume":"31","author":"Guerrerosantos","year":"2007","journal-title":"Aesthetic Plast. Surg."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"674","DOI":"10.1212\/WNL.61.5.674","article-title":"Parry-Romberg Syndrome: A Global Survey of 205 Patients Using the Internet","volume":"61","author":"Stone","year":"2003","journal-title":"Neurology"},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1016\/j.survophthal.2016.03.009","article-title":"Ophthalmological Manifestations of Parry-Romberg Syndrome","volume":"61","author":"Bucher","year":"2016","journal-title":"Surv. Ophthalmol."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1016\/j.jaad.2006.10.959","article-title":"En Coup de Sabre Morphea and Parry-Romberg Syndrome: A Retrospective Review of 54 Patients","volume":"56","author":"Tollefson","year":"2007","journal-title":"J. Am. Acad. Dermatol."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1007\/s12070-016-0981-5","article-title":"Parry Romberg Syndrome","volume":"71","author":"Khanduri","year":"2019","journal-title":"Indian J. Otolaryngol. Head Neck Surg."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1046\/j.1468-3083.2002.00442.x","article-title":"Scleroderma \u201cen coup de sabre\u201d and progressive facial hemiatrophy. is it possible to differentiate them?","volume":"16","year":"2002","journal-title":"J. Eur. Acad. Dermatol. Venereol."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/j.jaad.2005.10.020","article-title":"Clinical and Serological Characteristics of Progressive Facial Hemiatrophy: A Case Series of 12 Patients","volume":"54","author":"Sommer","year":"2006","journal-title":"J. Am. Acad. Dermatol."},{"key":"ref_30","first-page":"1997","article-title":"Progressive Facial Hemiatrophy: Central Nervous System Involvement and Relationship with Scleroderma En Coup de Sabre","volume":"30","author":"Blaszczyk","year":"2003","journal-title":"J. Rheumatol."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1111\/j.1552-6569.2009.00398.x","article-title":"Parry-Romberg Syndrome and Rasmussen Encephalitis: Possible Association. Clinical and Neuroimaging Features","volume":"21","author":"Longo","year":"2011","journal-title":"J. Neuroimaging"},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1097\/SAP.0b013e31818bed6d","article-title":"Parry-Romberg Syndrome: Facial Atrophy and Its Relationship with Other Regions of the Body","volume":"63","author":"Duymaz","year":"2009","journal-title":"Ann. Plast. Surg."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/0007-1226(93)90063-H","article-title":"Progressive Hemifacial Atrophy (Romberg\u2019s Disease): Skeletal Involvement and Treatment","volume":"46","author":"Moore","year":"1993","journal-title":"Br. J. Plast. Surg."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"4154","DOI":"10.1016\/j.acra.2025.02.030","article-title":"Neuroimaging and Clinical Features of Parry-Romberg Syndrome and Linear Morphea En-Coup-de-Sabre in a Large Case Series","volume":"32","author":"Gorolay","year":"2025","journal-title":"Acad. Radiol."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"27","DOI":"10.3928\/0191-3913-19870101-07","article-title":"Progressive Hemifacial Atrophy (Parry-Romberg Disease)","volume":"24","author":"Miller","year":"1987","journal-title":"J. Pediatr. Ophthalmol. Strabismus"},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1046\/j.1525-1470.2000.01757.x","article-title":"Bilateral En Coup de Sabre-a Rare Entity","volume":"17","author":"Rai","year":"2000","journal-title":"Pediatr. Dermatol."},{"key":"ref_37","doi-asserted-by":"crossref","unstructured":"Gambichler, T., Kreuter, A., Hoffmann, K., Bechara, F.G., Altmeyer, P., and Jansen, T. (2001). Bilateral linear scleroderma \u201cen coup de sabre\u201d associated with facial atrophy and neurological complications. BMC Dermatol., 1.","DOI":"10.1186\/1471-5945-1-9"},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"688","DOI":"10.1001\/archderm.1968.01610120078012","article-title":"Bilateral linear scleroderma en coup de sabre","volume":"97","author":"Dilley","year":"1968","journal-title":"Arch. Dermatol."},{"key":"ref_39","first-page":"287","article-title":"Progressive hemifacial atrophy in the young patient: Physiopathologic hypotheses, diagnosis and therapy","volume":"101","author":"Ruhin","year":"2000","journal-title":"Rev. Stomatol. Chir. Maxillofac."},{"key":"ref_40","first-page":"193","article-title":"Parry-Romberg Syndrome: A Mini Review","volume":"29","author":"Arif","year":"2020","journal-title":"Acta Dermatovenerol. Alp. Pannonica Adriat."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"97","DOI":"10.4103\/psychiatry.IndianJPsychiatry_340_17","article-title":"A Queer Case of Parry-Romberg Syndrome with Coexisting Psychiatric Ailment","volume":"61","author":"Chauhan","year":"2019","journal-title":"Indian J. Psychiatry"},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"849","DOI":"10.7326\/0003-4819-104-6-849","article-title":"Linear Scleroderma. Clinical Spectrum, Prognosis, and Laboratory Abnormalities","volume":"104","author":"Falanga","year":"1986","journal-title":"Ann. Intern. Med."},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"1013","DOI":"10.1212\/WNL.48.4.1013","article-title":"Progressive Facial Hemiatrophy and Epilepsy: A Common Underlying Dysgenetic Mechanism","volume":"48","author":"Dupont","year":"1997","journal-title":"Neurology"},{"key":"ref_44","first-page":"956","article-title":"Intracranial Findings in Progressive Facial Hemiatrophy","volume":"19","author":"Fry","year":"1992","journal-title":"J. Rheumatol."},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"866","DOI":"10.1016\/S0181-5512(05)81008-3","article-title":"Neuroretinitis, Parry-Romberg syndrome, and scleroderma","volume":"28","author":"Karim","year":"2005","journal-title":"J. Fr. Ophtalmol."},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"969","DOI":"10.1136\/jmg.31.12.969","article-title":"Progressive Hemifacial Atrophy with Agenesis of the Head of the Caudate Nucleus","volume":"31","year":"1994","journal-title":"J. Med. Genet."},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1007\/BF01824007","article-title":"Central Sympathetic Dysregulation and Immunological Abnormalities in a Case of Progressive Facial Hemiatrophy (Parry-Romberg Disease)","volume":"5","author":"Lonchampt","year":"1995","journal-title":"Clin. Auton. Res."},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/S0190-9622(00)90010-0","article-title":"Increased Serum Levels of Soluble Vascular Cell Adhesion Molecule 1 and E-Selectin in Patients with Localized Scleroderma","volume":"42","author":"Yamane","year":"2000","journal-title":"J. Am. Acad. Dermatol."},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"303e","DOI":"10.1097\/PRS.0000000000004638","article-title":"Changes in Cutaneous Gene Expression after Microvascular Free Tissue Transfer in Parry-Romberg Syndrome","volume":"142","author":"Chen","year":"2018","journal-title":"Plast. Reconstr. Surg."},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1016\/S1010-5182(03)00028-3","article-title":"Parry-Romberg Syndrome: Intracranial MRI Appearances","volume":"31","author":"Moko","year":"2003","journal-title":"J. Craniomaxillofac. Surg."},{"key":"ref_51","first-page":"169","article-title":"Parry-Romberg progressive facial hemiatrophy and localized scleroderma. Nosologic and pathogenic problems","volume":"12","author":"Auvinet","year":"1989","journal-title":"J. Fr. Ophtalmol."},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1007\/978-1-4615-4857-7_14","article-title":"Linear Scleroderma En Coup de Sabre. Relationship with Progressive Facial Hemiatrophy (PFH)","volume":"455","author":"Blaszczyk","year":"1999","journal-title":"Adv. Exp. Med. Biol."},{"key":"ref_53","first-page":"73","article-title":"Autoantibodies in Parry-Romberg Syndrome: A Serologic Study of 14 Patients","volume":"22","author":"Guerrerosantos","year":"1995","journal-title":"J. Rheumatol."},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"740","DOI":"10.1111\/j.1468-3083.2005.01290.x","article-title":"Parry-Romberg Syndrome in Association with Anti-dsDNA Antibodies: A Case Report","volume":"19","author":"Gonul","year":"2005","journal-title":"J. Eur. Acad. Dermatol. Venereol."},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"1400","DOI":"10.1136\/jnnp.2009.202044","article-title":"Neurological Picture. Contralateral Cutaneous and MRI Findings in a Patient with Parry-Romberg Syndrome","volume":"81","author":"Moseley","year":"2010","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1136\/jnnp.70.3.382","article-title":"Scleroderma \u201cEn Coup de Sabre\u201d: Pathological Evidence of Intracerebral Inflammation","volume":"70","author":"Stone","year":"2001","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1177\/03331024211043452","article-title":"Headache in Progressive Facial Hemiatrophy (Parry-Romberg Syndrome): A Paradigmatic Case and Systematic Review of the Literature","volume":"42","author":"Foiadelli","year":"2022","journal-title":"Cephalalgia"},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"183","DOI":"10.5624\/isd.2011.41.4.183","article-title":"Three-Dimensional Imaging of Progressive Facial Hemiatrophy (Parry-Romberg Syndrome) with Unusual Conjunctival Findings","volume":"41","author":"Balan","year":"2011","journal-title":"Imaging Sci. Dent."},{"key":"ref_59","first-page":"47","article-title":"Familial form of Parry-Romberg syndrome","volume":"40","author":"Ignatowicz","year":"1985","journal-title":"Pol. Tyg. Lek."},{"key":"ref_60","doi-asserted-by":"crossref","unstructured":"Ruggieri, M., Pascual-Castroviejo, I., and Di Rocco, C. (2008). Progressive Facial Hemiatrophy (Parry-Romberg Syndrome). Neurocutaneous Disorders Phakomatoses and Hamartoneoplastic Syndromes, Springer.","DOI":"10.1007\/978-3-211-69500-5"},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1016\/j.ijporl.2004.12.004","article-title":"Familial Parry-Romberg Disease","volume":"69","author":"Anderson","year":"2005","journal-title":"Int. J. Pediatr. Otorhinolaryngol."},{"key":"ref_62","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1002\/ajmg.1320140220","article-title":"Progressive Hemifacial Atrophy (Parry-Romberg Syndrome) Report with Review of Genetics and Nosology","volume":"14","author":"Lewkonia","year":"1983","journal-title":"Am. J. Med. Genet."},{"key":"ref_63","first-page":"8","article-title":"Syndrome de Parry-Romberg \u00e0 propos d\u2019un cas","volume":"5","author":"Doubi","year":"2015","journal-title":"IOSR J. Pharm."},{"key":"ref_64","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1038\/s41598-023-27597-1","article-title":"Genetic Variations in Patient with Parry-Romberg Syndrome","volume":"13","author":"Yu","year":"2023","journal-title":"Sci. Rep."},{"key":"ref_65","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1007\/s10072-008-0932-3","article-title":"Electrophysiological Findings in a Case of Congenital Lower Limb Hypoplasia","volume":"29","author":"Zambelis","year":"2008","journal-title":"Neurol. Sci."},{"key":"ref_66","doi-asserted-by":"crossref","first-page":"1195","DOI":"10.1097\/00006123-199805000-00161","article-title":"Progressive Intracranial Aneurysmal Disease in a Child with Progressive Hemifacial Atrophy (Parry-Romberg Disease): Case Report","volume":"42","author":"Catala","year":"1998","journal-title":"Neurosurgery"},{"key":"ref_67","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1016\/0190-9622(90)70051-I","article-title":"Parry-Romberg Syndrome in Association with Contralateral Poland Syndrome","volume":"22","author":"Dintiman","year":"1990","journal-title":"J. Am. Acad. Dermatol."},{"key":"ref_68","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1055\/s-2007-979779","article-title":"Progressive Facial Hemiatrophy with Multiple Benign Tumors and Hamartomas","volume":"26","author":"Derex","year":"1995","journal-title":"Neuropediatrics"},{"key":"ref_69","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1212\/WNL.59.4.606","article-title":"Parry-Romberg Syndrome with Migraine and Intracranial Aneurysm","volume":"59","author":"Pichiecchio","year":"2002","journal-title":"Neurology"},{"key":"ref_70","first-page":"e67345","article-title":"Parry-Romberg Syndrome: A Report of a Rare Case and a Comprehensive Review","volume":"16","author":"Marappan","year":"2024","journal-title":"Cureus"},{"key":"ref_71","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1007\/s12663-018-1147-7","article-title":"Parry Romberg Syndrome: Literature Review and Report of Three Cases","volume":"18","author":"Kumar","year":"2019","journal-title":"J. Maxillofac. Oral. Surg."},{"key":"ref_72","first-page":"543","article-title":"Facial hemiatrophy, homolateral cervical linear scleroderma and thyroid disease","volume":"119","author":"Claudy","year":"1992","journal-title":"Ann. Dermatol. Venereol."},{"key":"ref_73","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1001\/archneur.1982.00510130046011","article-title":"Progressive Hemifacial Atrophy: Report of Three Cases, Including One Observed over 43 Years, and Computed Tomographic Findings","volume":"39","author":"Asher","year":"1982","journal-title":"Arch. Neurol."},{"key":"ref_74","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1001\/archneurpsyc.1932.02230150045004","article-title":"Progressive facial hemiatrophy: Report of three cases","volume":"27","author":"Archambault","year":"1932","journal-title":"Arch. Neurol. Psychiatry"},{"key":"ref_75","first-page":"e41465","article-title":"Parry Romberg Syndrome: A Case Report and an Insight Into Etiology","volume":"15","author":"Kumar","year":"2023","journal-title":"Cureus"},{"key":"ref_76","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1590\/S0004-27492004000200029","article-title":"Uso de Polietigel\u00ae intra-orbit\u00e1rio em paciente com atrofia hemifacial progressiva: Relato de caso","volume":"67","author":"Kafuri","year":"2004","journal-title":"Arq. Bras. Oftalmol."},{"key":"ref_77","first-page":"48","article-title":"Parry\u2013Romberg Syndrome: An Orthodontic Perspective","volume":"3","author":"Arya","year":"2016","journal-title":"Int. J. Recent Surg. Med. Sci."},{"key":"ref_78","doi-asserted-by":"crossref","first-page":"15","DOI":"10.5348\/Z09-2016-12-CR-5","article-title":"Head Injury as a Trigger of Parry-Romberg Syndrome: A Case Report and Review of Etiology","volume":"2","author":"Azim","year":"2016","journal-title":"J. Case Rep. Images Med."},{"key":"ref_79","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/j.jdcr.2018.11.015","article-title":"Adult-Onset Bilateral Parry-Romberg Syndrome","volume":"5","author":"Tkachenko","year":"2019","journal-title":"JAAD Case Rep."},{"key":"ref_80","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1001\/archneurpsyc.1945.02300080003001","article-title":"Progressive facial hemiatrophy","volume":"54","author":"Wartenberg","year":"1945","journal-title":"Arch. Neurol. Psychiatry"},{"key":"ref_81","doi-asserted-by":"crossref","first-page":"387","DOI":"10.4103\/2231-0762.186792","article-title":"Parry\u2013Romberg Syndrome Affecting One Half of the Body","volume":"6","author":"Pathi","year":"2016","journal-title":"J. Int. Soc. Prev. Community Dent."},{"key":"ref_82","doi-asserted-by":"crossref","first-page":"68","DOI":"10.3329\/jssmc.v4i2.14424","article-title":"A 8 Years Old Girl Presented with Parry Romberg Syndrome Attended at Shaheed Suhrawardy Medical College Hospital: A Case Report","volume":"4","author":"Khan","year":"2012","journal-title":"J. Shaheed Suhrawardy Med. Coll."},{"key":"ref_83","first-page":"142","article-title":"S\u00edndrome de Parry Romberg","volume":"6","year":"2015","journal-title":"Rev. Cienc. Biom\u00e9dicas"},{"key":"ref_84","first-page":"637","article-title":"Facial Atrophy","volume":"3","author":"Rees","year":"1976","journal-title":"Clin. Plast. Surg."},{"key":"ref_85","doi-asserted-by":"crossref","first-page":"997","DOI":"10.1136\/jnnp.37.9.997","article-title":"Neurological Complications of Progressive Facial Hemiatrophy","volume":"37","author":"Wolf","year":"1974","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"key":"ref_86","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1111\/j.1468-3083.2004.00862.x","article-title":"Parry-Romberg Syndrome: A Possible Association with Borreliosis","volume":"18","author":"Sahin","year":"2004","journal-title":"J. Eur. Acad. Dermatol. Venereol."},{"key":"ref_87","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1097\/00006534-199209000-00020","article-title":"Progressive Hemifacial Atrophy Associated with Lyme Disease","volume":"90","author":"Stern","year":"1992","journal-title":"Plast. Reconstr. Surg."},{"key":"ref_88","first-page":"609","article-title":"Experimental study of progressive facial hemiatrophy: Effects of cervical sympathectomy in animals","volume":"147","author":"Resende","year":"1991","journal-title":"Rev. Neurol."},{"key":"ref_89","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1016\/0003-9969(60)90052-2","article-title":"Progressive Facial Hemiatrophy Following Cervical Sympathectomy in the Rat","volume":"1","author":"Moss","year":"1960","journal-title":"Arch. Oral. Biol."},{"key":"ref_90","first-page":"557","article-title":"Optic neuropathy and Parry-Romberg syndrome. Apropos of a case","volume":"13","author":"Garcher","year":"1990","journal-title":"J. Fr. Ophtalmol."},{"key":"ref_91","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1097\/00006534-199005000-00001","article-title":"Clinical and Ultrastructural Studies of Romberg\u2019s Hemifacial Atrophy","volume":"85","author":"Pensler","year":"1990","journal-title":"Plast. Reconstr. Surg."},{"key":"ref_92","first-page":"751","article-title":"Clinical and Radiologic Findings in Progressive Facial Hemiatrophy (Parry-Romberg Syndrome)","volume":"18","author":"Cory","year":"1997","journal-title":"AJNR Am. J. Neuroradiol."},{"key":"ref_93","doi-asserted-by":"crossref","first-page":"i3","DOI":"10.1136\/jnnp.74.suppl_1.i3","article-title":"Congenital Abnormalities of the Central Nervous System","volume":"74","author":"Verity","year":"2003","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"key":"ref_94","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1097\/SCS.0b013e31820fe27d","article-title":"Combined Skeletal and Soft Tissue Reconstruction for Severe Parry-Romberg Syndrome","volume":"22","author":"Hu","year":"2011","journal-title":"J. Craniofac. Surg."},{"key":"ref_95","first-page":"57","article-title":"Therapeutic approTherapeutic Approach To The Parry-Romberg Syndrome Based On A Severity Grading System","volume":"29","author":"Denadai","year":"2001","journal-title":"Rev. Bras. Cir. Pl\u00e1stica"},{"key":"ref_96","doi-asserted-by":"crossref","first-page":"bcr1020114920","DOI":"10.1136\/bcr.10.2011.4920","article-title":"Aneurysmal Subarachnoid Haemorrhage in Parry-Rhomberg Syndrome","volume":"2011","author":"Kuechler","year":"2011","journal-title":"BMJ Case Rep."},{"key":"ref_97","first-page":"73","article-title":"S\u00edndrome de Parry-Romberg asociado a infarto cerebral con epilepsia refractaria: Reporte de un caso","volume":"45","author":"Cuevas","year":"2019","journal-title":"Rev. Chil. Neurocir."},{"key":"ref_98","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1186\/s13256-019-2063-2","article-title":"Parry-Romberg Syndrome Associated with En Coup de Sabre in a Patient from South Sudan\u2014A Rare Entity from East Africa: A Case Report","volume":"13","author":"Abdelnour","year":"2019","journal-title":"J. Med. Case Rep."},{"key":"ref_99","doi-asserted-by":"crossref","first-page":"6208","DOI":"10.1016\/j.radcr.2024.09.029","article-title":"Parry Romberg Syndrome: A Case Report","volume":"19","author":"Afreh","year":"2024","journal-title":"Radiol. Case Rep."},{"key":"ref_100","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/j.jocn.2020.04.024","article-title":"Parry Romberg Syndrome: Imaging Features in 4 Consecutive Cases and Review of Literature","volume":"76","author":"Ahmed","year":"2020","journal-title":"J. Clin. Neurosci."},{"key":"ref_101","doi-asserted-by":"crossref","first-page":"2377","DOI":"10.1007\/s00381-018-3934-3","article-title":"Clinico-Radiological Approach to Cerebral Hemiatrophy","volume":"34","author":"Tan","year":"2018","journal-title":"Childs Nerv. Syst."},{"key":"ref_102","doi-asserted-by":"crossref","first-page":"511","DOI":"10.26442\/20751753.2022.8.201831","article-title":"Syndrom Parry\u2013Romberg: Clinical case of a rare disease","volume":"24","author":"Perlamutrov","year":"2022","journal-title":"Cons. Medicum"},{"key":"ref_103","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1016\/j.semarthrit.2013.05.002","article-title":"Neurologic Involvement in Scleroderma: A Systematic Review","volume":"43","author":"Amaral","year":"2013","journal-title":"Semin. Arthritis Rheum."},{"key":"ref_104","doi-asserted-by":"crossref","first-page":"e313","DOI":"10.4317\/jced.51409","article-title":"Parry Romberg Syndrome with Localized Scleroderma: A Case Report","volume":"6","author":"Khan","year":"2014","journal-title":"J. Clin. Exp. Dent."},{"key":"ref_105","first-page":"5","article-title":"Parry Romberg & Morphea en Coup de Sabre","volume":"39","author":"Ekert","year":"2018","journal-title":"Rofo"},{"key":"ref_106","doi-asserted-by":"crossref","first-page":"738","DOI":"10.1111\/pde.12001","article-title":"A Significant Proportion of Children with Morphea En Coup de Sabre and Parry-Romberg Syndrome Have Neuroimaging Findings","volume":"29","author":"Chiu","year":"2012","journal-title":"Pediatr. Dermatol."},{"key":"ref_107","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1007\/s12663-010-0103-y","article-title":"Parry-Romberg Syndrome: A Rare Entity","volume":"9","author":"Patel","year":"2010","journal-title":"J. Maxillofac. Oral. Surg."},{"key":"ref_108","first-page":"103","article-title":"Unilateral Facial Asymmetry: Do Not Forget to Look at the Subcutaneous Tissue","volume":"3","author":"Yadav","year":"2025","journal-title":"Case Rep. Clin. Radiol."},{"key":"ref_109","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1111\/j.1469-8749.1997.tb07469.x","article-title":"Progressive Facial Hemiatrophy: MRI Appearances","volume":"39","author":"Taylor","year":"1997","journal-title":"Dev. Med. Child. Neurol."},{"key":"ref_110","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1016\/S0887-8994(01)00333-2","article-title":"Parry-Romberg Syndrome Associated with Adie\u2019s Pupil and Radiologic Findings","volume":"25","author":"Aynaci","year":"2001","journal-title":"Pediatr. Neurol."},{"key":"ref_111","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1016\/j.yebeh.2004.11.012","article-title":"Cortical Silent Period in a Patient with Focal Epilepsy and Parry-Romberg Syndrome","volume":"6","author":"Aktekin","year":"2005","journal-title":"Epilepsy Behav."},{"key":"ref_112","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1016\/j.jpeds.2004.10.026","article-title":"Parry-Romberg Syndrome with Fatal Brain Stem Involvement","volume":"146","author":"Sathornsumetee","year":"2005","journal-title":"J. Pediatr."},{"key":"ref_113","first-page":"941","article-title":"Parry Romberg syndrome associated with refractory epilepsy, atrophy of the dura mater and cystic leukoencephalopathy","volume":"37","year":"2003","journal-title":"Rev. Neurol."},{"key":"ref_114","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1111\/j.0736-8046.2004.21109.x","article-title":"Subdural Hygroma in a Patient with Parry-Romberg Syndrome","volume":"21","author":"Sandhu","year":"2004","journal-title":"Pediatr. Dermatol."},{"key":"ref_115","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1590\/S0004-282X1982000200011","article-title":"Progressive hemifacial atrophy (Parry-Romberg disease): Study of a case","volume":"40","author":"Duro","year":"1982","journal-title":"Arq. Neuropsiquiatr."},{"key":"ref_116","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1016\/S0887-8994(00)00168-5","article-title":"Progressive Facial Hemiatrophy after Epileptic Seizures","volume":"23","author":"Yano","year":"2000","journal-title":"Pediatr. Neurol."},{"key":"ref_117","doi-asserted-by":"crossref","first-page":"1146","DOI":"10.1111\/j.1468-2982.2006.01161.x","article-title":"Trigeminal Neuralgia, Migraine and Sympathetic Hyperactivity in a Patient with Parry-Romberg Syndrome","volume":"26","author":"Drummond","year":"2006","journal-title":"Cephalalgia"},{"key":"ref_118","first-page":"497","article-title":"Progressive Hemifacial Atrophy\u2014A Report of 2 Cases","volume":"31","author":"Ong","year":"1990","journal-title":"Singap. Med. J."},{"key":"ref_119","doi-asserted-by":"crossref","first-page":"6776","DOI":"10.4076\/1757-1626-2-6776","article-title":"Progressive Hemi Facial Atrophy\u2014Parry Romberg Syndrome Presenting as Severe Facial Pain in a Young Man: A Case Report","volume":"2","author":"Kumar","year":"2009","journal-title":"Cases J."},{"key":"ref_120","doi-asserted-by":"crossref","first-page":"938","DOI":"10.1001\/archneurol.2011.126","article-title":"Trigeminal Neuropathic Pain in a Patient with Progressive Facial Hemiatrophy (Parry-Romberg Syndrome)","volume":"68","author":"Viana","year":"2011","journal-title":"Arch. Neurol."},{"key":"ref_121","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1007\/s10194-012-0459-0","article-title":"Cutaneous Innervation and Trigeminal Pathway Function in a Patient with Facial Pain Associated with Parry-Romberg Syndrome","volume":"13","author":"Falla","year":"2012","journal-title":"J. Headache Pain"},{"key":"ref_122","doi-asserted-by":"crossref","first-page":"1320","DOI":"10.1016\/j.jocn.2012.08.020","article-title":"Parry Romberg Syndrome Associated with Chronic Facial Pain","volume":"20","author":"Colombo","year":"2013","journal-title":"J. Clin. Neurosci."},{"key":"ref_123","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/j.pjnns.2016.02.002","article-title":"Mild Cognitive Impairment as a Single Sign of Brain Hemiatrophy in Patient with Localized Scleroderma and Parry-Romberg Syndrome","volume":"50","author":"Klimiec","year":"2016","journal-title":"Neurol. Neurochir. Pol."},{"key":"ref_124","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1002\/acr2.11410","article-title":"Clinical Images: Parry-Romberg Syndrome","volume":"4","author":"Bukiej","year":"2022","journal-title":"ACR Open Rheumatol."},{"key":"ref_125","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1111\/j.1365-263X.2006.00730.x","article-title":"Parry-Romberg Syndrome: A Report of the Dental Findings in a Child Followed up for 9 Years","volume":"16","author":"Kinirons","year":"2006","journal-title":"Int. J. Paediatr. Dent."},{"key":"ref_126","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1016\/S0099-2399(06)80821-6","article-title":"Root Resorptions in a Patient with Hemifacial Atrophy","volume":"20","author":"Fayad","year":"1994","journal-title":"J. Endod."},{"key":"ref_127","first-page":"e47397","article-title":"Parry Romberg Syndrome: When the Diagnosis of a Rare Disease Is Made in the Primary Care Setting","volume":"15","author":"Pereira","year":"2023","journal-title":"Cureus"},{"key":"ref_128","doi-asserted-by":"crossref","unstructured":"Hashemi, H.M., Mohammadi, F., Kahnamouii, S.S., Hashemi, H.M., Mohammadi, F., and Kahnamouii, S.S. (2016). Advances in Craniofacial Surgery. A Textbook of Advanced Oral and Maxillofacial Surgery Volume 3, IntechOpen.","DOI":"10.5772\/63739"},{"key":"ref_129","doi-asserted-by":"crossref","first-page":"780","DOI":"10.1016\/j.jcms.2013.11.010","article-title":"Parry-Romberg Syndrome with Rare Maxillofacial Deformities: A Report on Two Cases","volume":"42","author":"Tang","year":"2014","journal-title":"J. Craniomaxillofac. Surg."},{"key":"ref_130","doi-asserted-by":"crossref","first-page":"909","DOI":"10.1016\/j.jcms.2019.03.032","article-title":"Craniofacial Bone Atrophy in Parry Romberg Syndrome Demonstrated Using a Bayesian Hierarchical Model","volume":"47","author":"Hennocq","year":"2019","journal-title":"J. Craniomaxillofac. Surg."},{"key":"ref_131","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/S0901-5027(88)80020-1","article-title":"Unilateral Osteolysis of the Mandibular Angle and Coronoid Process in Scleroderma","volume":"17","author":"Pogrel","year":"1988","journal-title":"Int. J. Oral Maxillofac. Surg."},{"key":"ref_132","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1259\/dmfr\/14556986","article-title":"Mandibular Resorption in Progressive Systemic Sclerosis: A Report of Three Cases","volume":"34","author":"Auluck","year":"2005","journal-title":"Dentomaxillofac. Radiol."},{"key":"ref_133","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1016\/0030-4220(87)90188-5","article-title":"Mandibular Condylosis and Apertognathia as Presenting Symptoms in Progressive Systemic Sclerosis (Scleroderma): Pattern of Mandibular Bony Lesions and Atrophy of Masticatory Muscles in PSS, Presumably Caused by Affected Muscular Arteries","volume":"63","author":"Ramon","year":"1987","journal-title":"Oral Surg. Oral Med. Oral Pathol."},{"key":"ref_134","first-page":"88","article-title":"Parry-Romberg syndrome and odontogenic cyst. A case report","volume":"101","author":"Beluffi","year":"2001","journal-title":"Radiol. Med."},{"key":"ref_135","first-page":"763","article-title":"Observations on a case of odontoma of the mandible associated with parry-romberg syndrome","volume":"24","author":"Fietta","year":"1963","journal-title":"Riv. Anat. Patol. Oncol."},{"key":"ref_136","doi-asserted-by":"crossref","first-page":"160","DOI":"10.25259\/IJPGD_50_2025","article-title":"Parry\u2013Romberg Syndrome Associated with Hypothyroidism","volume":"3","author":"Shivani","year":"2025","journal-title":"Indian J. Postgrad. Dermatol."},{"key":"ref_137","doi-asserted-by":"crossref","first-page":"857","DOI":"10.3341\/jkos.2017.58.7.857","article-title":"Parry-Romberg Syndrome Associated with Hypothyroidism","volume":"58","author":"Lee","year":"2017","journal-title":"J. Korean Ophthalmol. Soc."},{"key":"ref_138","doi-asserted-by":"crossref","first-page":"157","DOI":"10.14581\/jer.19020","article-title":"Parry-Romberg Syndrome and Temporal Lobe Refractory Epilepsy: Case Report","volume":"9","author":"Pradilla","year":"2019","journal-title":"J. Epilepsy Res."},{"key":"ref_139","doi-asserted-by":"crossref","first-page":"2050313X211034351","DOI":"10.1177\/2050313X211034351","article-title":"A Case of Parasympathetic Hyperactivity and Associated Parry-Romberg Syndrome","volume":"9","author":"Clapp","year":"2021","journal-title":"SAGE Open Med. Case Rep."},{"key":"ref_140","first-page":"E112","article-title":"Progressive Hemifacial Atrophy\u2014Case Report","volume":"11","author":"Pinheiro","year":"2006","journal-title":"Med. Oral Patol. Oral Cir. Bucal"},{"key":"ref_141","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1007\/s10072-011-0756-4","article-title":"Parry-Romberg Syndrome: Clinical, Electrophysiological and Neuroimaging Correlations","volume":"33","author":"Budrewicz","year":"2012","journal-title":"Neurol. Sci."},{"key":"ref_142","doi-asserted-by":"crossref","first-page":"1019","DOI":"10.1136\/annrheumdis-2018-214697","article-title":"Consensus-Based Recommendations for the Management of Juvenile Localised Scleroderma","volume":"78","author":"Zulian","year":"2019","journal-title":"Ann. Rheum. Dis."},{"key":"ref_143","doi-asserted-by":"crossref","first-page":"620","DOI":"10.1002\/ana.410170621","article-title":"Hemiplegic Migraine and Progressive Hemifacial Atrophy","volume":"17","author":"Sagild","year":"1985","journal-title":"Ann. Neurol."},{"key":"ref_144","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1007\/s00234-014-1448-6","article-title":"CNS Imaging Findings Associated with Parry-Romberg Syndrome and En Coup de Sabre: Correlation to Dermatologic and Neurologic Abnormalities","volume":"57","author":"Doolittle","year":"2015","journal-title":"Neuroradiology"},{"key":"ref_145","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1590\/0100-3984.2013.1699","article-title":"S\u00edndrome de Parry-Romberg: Achados nas sequ\u00eancias avan\u00e7adas de resson\u00e2ncia magn\u00e9tica\u2014Relato de caso","volume":"47","author":"Ribeiro","year":"2014","journal-title":"Radiol. Bras."},{"key":"ref_146","first-page":"1729","article-title":"Parry-Romberg Syndrome with a Clinically Silent White Matter Lesion","volume":"27","author":"Okumura","year":"2006","journal-title":"AJNR Am. J. Neuroradiol."},{"key":"ref_147","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1177\/1971400916689577","article-title":"Parry-Romberg Syndrome: Conventional and Advanced MRI Follow-up in a Boy","volume":"30","author":"Rigamonti","year":"2017","journal-title":"Neuroradiol. J."},{"key":"ref_148","doi-asserted-by":"crossref","first-page":"368","DOI":"10.17712\/nsj.2015.4.20150142","article-title":"Parry-Romberg Syndrome. Physical, Clinical, and Imaging Features","volume":"20","author":"Yologlu","year":"2015","journal-title":"Neurosciences"},{"key":"ref_149","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1007\/s001050050946","article-title":"Was bringt die Magnetresonanztomographie in der Beurteilung der Romberg-Erkrankung?","volume":"50","author":"Schlecht","year":"1999","journal-title":"Hautarzt"},{"key":"ref_150","doi-asserted-by":"crossref","first-page":"41","DOI":"10.17352\/2455-1414.000019","article-title":"Goldenhar Syndrome","volume":"2","author":"Costea","year":"2015","journal-title":"J. Clin. Res. Ophthalmol."},{"key":"ref_151","doi-asserted-by":"crossref","first-page":"940","DOI":"10.1097\/01.smj.0000177355.43001.ff","article-title":"Beneficial Effect of Immunosuppressive Drugs on Parry-Romberg Syndrome: A Case Report and Review of the Literature","volume":"98","author":"Korkmaz","year":"2005","journal-title":"South. Med. J."},{"key":"ref_152","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1111\/j.1600-0781.2006.00238.x","article-title":"Parry-Romberg Syndrome Associated with Borreliosis: Could Photochemotherapy Halt the Progression of the Disease?","volume":"22","author":"Baskan","year":"2006","journal-title":"Photodermatol. Photoimmunol. Photomed."},{"key":"ref_153","doi-asserted-by":"crossref","first-page":"534","DOI":"10.1007\/s00266-010-9480-3","article-title":"Superficial Temporal Fascial Flap plus Lipofilling for Facial Contour Reconstruction in Bilateral Progressive Facial Hemiatrophy","volume":"34","author":"Ye","year":"2010","journal-title":"Aesthetic Plast. Surg."},{"key":"ref_154","doi-asserted-by":"crossref","first-page":"e20","DOI":"10.1016\/j.tripleo.2009.09.017","article-title":"Use of Autologous Fat Graft for Correction of Facial Asymmetry Stemming from Parry-Romberg Syndrome","volume":"109","author":"Avelar","year":"2010","journal-title":"Oral Surg. Oral Med. Oral Pathol. Oral Radiol. Endod."},{"key":"ref_155","doi-asserted-by":"crossref","first-page":"1104","DOI":"10.1097\/SCS.0b013e318176ac6c","article-title":"Reconstruction with Galeal Frontalis Flap of Depressed Forehead Region in Progressive Hemifacial Atrophy","volume":"19","author":"Duymaz","year":"2008","journal-title":"J. Craniofac. Surg."},{"key":"ref_156","first-page":"49","article-title":"Free fat flap for the treatment of Parry-Romberg disease in children","volume":"18","author":"Berenguer","year":"2005","journal-title":"Cir. Pediatr."},{"key":"ref_157","doi-asserted-by":"crossref","first-page":"696","DOI":"10.1097\/00001665-200607000-00016","article-title":"Treatment of \u201cen Coup de Sabre\u201d Deformity with Porous Polyethylene Implant","volume":"17","author":"Ozturk","year":"2006","journal-title":"J. Craniofac. Surg."},{"key":"ref_158","doi-asserted-by":"crossref","first-page":"2174","DOI":"10.3899\/jrheum.100062","article-title":"En Coup de Sabre Scleroderma and Parry-Romberg Syndrome in Adolescents: Surgical Options and Patient-Related Outcomes","volume":"37","author":"Palmero","year":"2010","journal-title":"J. Rheumatol."},{"key":"ref_159","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1007\/s002669900134","article-title":"The Expanded Polytetrafluoroethylene (ePTFE) in the Surgical Treatment of Parry-Romberg Syndrome: Case Report","volume":"21","author":"Saccomanno","year":"1997","journal-title":"Aesthetic Plast. Surg."},{"key":"ref_160","doi-asserted-by":"crossref","first-page":"1368","DOI":"10.1111\/j.1524-4725.2009.01243.x","article-title":"Volumetric Correction Using Poly-L-Lactic Acid in Facial Asymmetry: Parry Romberg Syndrome and Scleroderma","volume":"35","author":"Onesti","year":"2009","journal-title":"Dermatol. Surg."},{"key":"ref_161","first-page":"1178","article-title":"Cell-Assisted Lipotransfer for Facial Lipoatrophy: Efficacy of Clinical Use of Adipose-Derived Stem Cells","volume":"34","author":"Yoshimura","year":"2008","journal-title":"Dermatol. Surg."},{"key":"ref_162","doi-asserted-by":"crossref","first-page":"e424","DOI":"10.1016\/j.bjps.2008.04.045","article-title":"Autologous Fat Transplantation for the Treatment of Parry-Romberg Syndrome","volume":"62","author":"Sterodimas","year":"2009","journal-title":"J. Plast. Reconstr. Aesthet. Surg."},{"key":"ref_163","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1016\/j.jcms.2010.02.005","article-title":"Parry-Romberg Syndrome: Volumetric Regeneration by Structural Fat Grafting Technique","volume":"38","author":"Clauser","year":"2010","journal-title":"J. Craniomaxillofac. Surg."},{"key":"ref_164","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1016\/j.bjoms.2009.06.021","article-title":"Facial Reconstruction with Vascularised Serratus Anterior Muscle Flap in Patients with Parry-Romberg Syndrome","volume":"48","author":"Cheng","year":"2010","journal-title":"Br. J. Oral. Maxillofac. Surg."},{"key":"ref_165","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1097\/SCS.0b013e31819b9e64","article-title":"Pedicled Superficial Temporal Fascia Sandwich Flap for Reconstruction of Severe Facial Depression","volume":"20","author":"Zhang","year":"2009","journal-title":"J. Craniofac. Surg."},{"key":"ref_166","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1055\/s-2007-992349","article-title":"Perforator-Based Anterolateral Thigh Adipofascial or Dermal Fat Flaps for Facial Contour Augmentation","volume":"23","author":"Wolff","year":"2007","journal-title":"J. Reconstr. Microsurg."},{"key":"ref_167","first-page":"40","article-title":"The thoracodorsal flap in facial reconstruction","volume":"74","author":"Malakhovskaia","year":"1995","journal-title":"Stomatologiia"},{"key":"ref_168","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1055\/s-2008-1080536","article-title":"Combined Treatments of Facial Contour Deformities Resulting from Parry-Romberg Syndrome","volume":"24","author":"Liu","year":"2008","journal-title":"J. Reconstr. Microsurg."},{"key":"ref_169","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1097\/01.prs.0000177449.12366.48","article-title":"Parascapular Free Flap and Fat Grafts: Combined Surgical Methods in Morphological Restoration of Hemifacial Progressive Atrophy","volume":"116","author":"Vaienti","year":"2005","journal-title":"Plast. Reconstr. Surg."},{"key":"ref_170","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1007\/s00266-008-9287-7","article-title":"Minimally Invasive Combined Treatment for Parry-Romberg Syndrome","volume":"33","author":"Onesti","year":"2009","journal-title":"Aesthetic Plast. Surg."},{"key":"ref_171","doi-asserted-by":"crossref","first-page":"1089","DOI":"10.1097\/SCS.0b013e318176354a","article-title":"Lipostructure Technique in Romberg Syndrome","volume":"19","author":"Grimaldi","year":"2008","journal-title":"J. Craniofac. Surg."},{"key":"ref_172","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1007\/s00266-008-9223-x","article-title":"Use of Cell Fat Mixed with Platelet Gel in Progressive Hemifacial Atrophy","volume":"33","author":"Cervelli","year":"2009","journal-title":"Aesthetic Plast. 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