{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,11]],"date-time":"2026-05-11T21:09:25Z","timestamp":1778533765110,"version":"3.51.4"},"reference-count":20,"publisher":"MDPI AG","issue":"9","license":[{"start":{"date-parts":[[2026,4,24]],"date-time":"2026-04-24T00:00:00Z","timestamp":1776988800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostics"],"abstract":"<jats:p>Background and Clinical Significance: To describe two cases within the spectrum of non-myopic foveomacular retinoschisis, including stellate non-hereditary idiopathic foveomacular retinoschisis (SNIFR) and central anomalous retinoschisis with mid-peripheral traction (CARPET), and to highlight the role of multimodal imaging in identifying vitreoretinal traction in their pathogenesis and management. Case Presentation:First Case Report: A 57-year-old man presenting with bilateral visual decline. Multimodal imaging, including spectral-domain and en face optical coherence tomography (OCT), demonstrated characteristic features of SNIFR, with schisis at the Henle fibre layer and outer plexiform layer and persistent posterior hyaloid adhesion. Medical treatment was ineffective. Over two years, complete posterior vitreous detachment occurred, followed by spontaneous anatomical resolution of the schisis and full visual recovery. Second Case Report: A 63-year-old man with severe unilateral visual loss. Imaging revealed marked mid-peripheral vitreoretinal traction extending toward the posterior pole; associated with foveoschisis, central neurosensory detachment, and an outer lamellar macular hole, consistent with CARPET syndrome. The patient underwent pars plana vitrectomy with traction release. Postoperatively, complete anatomical resolution of both macular and peripheral schisis was achieved, with partial visual recovery. Conclusions: These cases support vitreoretinal traction as an important pathogenic mechanism in selected forms of non-myopic foveomacular retinoschisis. SNIFR may resolve spontaneously following posterior vitreous detachment, whereas CARPET represents a more severe tractional phenotype that may require surgical intervention. Careful multimodal imaging assessment of the vitreoretinal interface is essential for accurate diagnosis and management. These findings further characterise CARPET and expand the clinical spectrum of traction-related non-myopic foveomacular retinoschisis.<\/jats:p>","DOI":"10.3390\/diagnostics16091285","type":"journal-article","created":{"date-parts":[[2026,4,24]],"date-time":"2026-04-24T14:28:23Z","timestamp":1777040903000},"page":"1285","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Non-Myopic Foveomacular Retinoschisis: Stellate Non-Hereditary Idiopathic Foveomacular Retinoschisis (SNIFR) and Central Anomalous Retinoschisis with Mid-Peripheral Traction (CARPET)"],"prefix":"10.3390","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9636-0788","authenticated-orcid":false,"given":"Jos\u00e9 M\u00aa","family":"Ruiz-Moreno","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, Puerta de Hierro-Majadahonda University Hospital, 28222 Madrid, Spain"},{"name":"Ocular Microsurgery Institute (IMO), 28035 Madrid, Spain"},{"name":"Department of Ophthalmology, Castilla-La Mancha University, 02008 Albacete, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Margarita","family":"Zamorano","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Puerta de Hierro-Majadahonda University Hospital, 28222 Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5557-6822","authenticated-orcid":false,"given":"Mariluz","family":"Puertas","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Puerta de Hierro-Majadahonda University Hospital, 28222 Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1105-9265","authenticated-orcid":false,"given":"Jorge","family":"Ruiz-Medrano","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Puerta de Hierro-Majadahonda University Hospital, 28222 Madrid, Spain"},{"name":"Ocular Microsurgery Institute (IMO), 28035 Madrid, Spain"},{"name":"Medical School, Universidad Aut\u00f3noma de Madrid, 28049 Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2026,4,24]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1406","DOI":"10.1016\/j.ophtha.2014.02.002","article-title":"Stellate nonhereditary idiopathic foveomacular retinoschisis","volume":"121","author":"Ober","year":"2014","journal-title":"Ophthalmology"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1016\/j.oret.2025.01.019","article-title":"Stellate Nonhereditary Idiopathic Foveomacular Retinoschisis and Central Anomalous Retinoschisis with mid-PEripheral Traction","volume":"9","author":"Feo","year":"2025","journal-title":"Ophthalmol. Retina"},{"key":"ref_3","first-page":"763","article-title":"Diseases of the optic nerve that may simulate macular disease","volume":"83","author":"Gass","year":"1977","journal-title":"Trans. Sect. Ophthalmol. Am. Acad. Ophthalmol. Otolaryngol."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"266","DOI":"10.3109\/01658107.2015.1092561","article-title":"Final diagnosis in patients referred with a diagnosis of neuroretinitis","volume":"39","author":"Kahloun","year":"2015","journal-title":"Neuroophthalmology"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"535","DOI":"10.3109\/08820538.2015.1132331","article-title":"Unilateral macular star in a case of hypertension and retinitis pigmentosa","volume":"32","author":"Chawla","year":"2017","journal-title":"Semin. Ophthalmol."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1016\/j.survophthal.2023.01.008","article-title":"Typical and atypical clinical presentations of X-Linked retinoschisis: A case series and literature review","volume":"68","author":"Wakabayashi","year":"2023","journal-title":"Surv. Ophthalmol."},{"key":"ref_7","first-page":"247","article-title":"Optic disc pit maculopathy: A review","volume":"8","author":"Kalogeropoulos","year":"2019","journal-title":"Asia-Pac. J. Ophthalmol."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"1607","DOI":"10.1007\/s00417-020-04755-z","article-title":"Optical coherence tomography characteristics of taxane-induced macular edema and other multimodal imaging findings","volume":"258","author":"Perez","year":"2020","journal-title":"Graefes Arch. Clin. Exp. Ophthalmol."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"e9","DOI":"10.1016\/j.oret.2024.06.009","article-title":"Stellate nonhereditary idiopathic foveomacular retinoschisis with bilateral peripheral retinoschisis","volume":"9","author":"Bommakanti","year":"2025","journal-title":"Ophthalmol. Retina"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"774","DOI":"10.3928\/23258160-20160808-12","article-title":"Widefield OCT findings of a patient with stellate nonhereditary idiopathic foveomacular retinoschisis","volume":"47","author":"Mandell","year":"2016","journal-title":"Ophthalmic Surg. Lasers Imaging Retina"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"S92","DOI":"10.1097\/ICB.0000000000000672","article-title":"Atypical peripapillary inner retinoschisis in stellate nonhereditary idiopathic foveomacular retinoschisis","volume":"12","author":"Javaheri","year":"2018","journal-title":"Retin. Cases Brief Rep."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"2361","DOI":"10.1097\/IAE.0000000000003191","article-title":"An association between stellate nonhereditary idiopathic foveomacular retinoschisis, peripheral retinoschisis, and posterior hyaloid attachment","volume":"41","author":"Bloch","year":"2021","journal-title":"Retina"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1097\/ICB.0000000000000966","article-title":"Vitrectomy for stellate nonhereditary idiopathic foveomacular retinoschisis associated with outer retinal layer defect","volume":"16","author":"Moraes","year":"2022","journal-title":"Retin. Cases Brief Rep."},{"key":"ref_14","doi-asserted-by":"crossref","unstructured":"Liu, J., Wang, Y., and Wang, L. (2023). Stellate nonheritable idiopathic foveomacular retinoschisis in juveniles: Case report. BMC Ophthalmol., 23.","DOI":"10.1186\/s12886-023-03142-6"},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1097\/ICB.0000000000001132","article-title":"Stellate nonhereditary idiopathic foveomacular retinoschisis: Novel findings and optical coherence tomography angiography analysis","volume":"17","author":"Schildroth","year":"2023","journal-title":"Retin. Cases Brief Rep."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.preteyeres.2018.03.006","article-title":"The primate fovea: Structure, function and development","volume":"66","author":"Bringmann","year":"2018","journal-title":"Prog. Retin. Eye Res."},{"key":"ref_17","first-page":"147","article-title":"Physiology of vitreous surgery","volume":"247","year":"2008","journal-title":"Graefes Arch. Clin. Exp. Ophthalmol."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.ajo.2019.12.010","article-title":"Distinctive mechanisms and patterns of exudative versus tractional intraretinal cystoid spaces as seen with multimodal imaging","volume":"212","author":"Govetto","year":"2020","journal-title":"Am. J. Ophthalmol."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1097\/ICB.0000000000000599","article-title":"Retinosquisis foveomacular idiop\u00e1tica no hereditaria estrellada: Respuesta al tratamiento t\u00f3pico con dorzolamida","volume":"13","author":"Ajlan","year":"2019","journal-title":"Retin. Cases Brief Rep."},{"key":"ref_20","first-page":"4418","article-title":"Complete spontaneous resolution of bilateral stellate nonhereditary idiopathic foveomacular retinoschisis","volume":"65","author":"Yu","year":"2024","journal-title":"Investig. Ophthalmol. Vis. Sci."}],"container-title":["Diagnostics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2075-4418\/16\/9\/1285\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,11]],"date-time":"2026-05-11T20:26:10Z","timestamp":1778531170000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2075-4418\/16\/9\/1285"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4,24]]},"references-count":20,"journal-issue":{"issue":"9","published-online":{"date-parts":[[2026,5]]}},"alternative-id":["diagnostics16091285"],"URL":"https:\/\/doi.org\/10.3390\/diagnostics16091285","relation":{},"ISSN":["2075-4418"],"issn-type":[{"value":"2075-4418","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4,24]]}}}