{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T05:03:16Z","timestamp":1780462996485,"version":"3.54.1"},"reference-count":10,"publisher":"MDPI AG","issue":"11","license":[{"start":{"date-parts":[[2026,5,26]],"date-time":"2026-05-26T00:00:00Z","timestamp":1779753600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostics"],"abstract":"<jats:p>A 46-year-old woman presented with persistent right knee pain and swelling six months after a fall. MRI initially showed a lateral meniscus tear, leading to meniscus repair and later meniscectomy, but symptoms persisted. Retrospective review of the MRI revealed edema in the tibial plateau and distal femoral condyle. Arthroscopic debridement demonstrated severe synovitis, marked cartilage loss of the lateral femoral condyle with a loose body, and tibial plateau cartilage damage. Bone SPECT\/CT showed bony destruction, cleft formation, and focal tracer uptake in the distal femur and proximal tibia. Femoral osteochondritis dissecans and a tibial osteochondral defect were diagnosed based on arthroscopic and imaging findings.<\/jats:p>","DOI":"10.3390\/diagnostics16111630","type":"journal-article","created":{"date-parts":[[2026,5,26]],"date-time":"2026-05-26T16:17:58Z","timestamp":1779812278000},"page":"1630","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Femoral Osteochondritis Dissecans and Tibial Osteochondral Defect in an Adult Revealed by Bone SPECT\/CT"],"prefix":"10.3390","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6325-046X","authenticated-orcid":false,"given":"Tzyy-Ling","family":"Chuang","sequence":"first","affiliation":[{"name":"Department of Nuclear Medicine, Dalin Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Chiayi 622401, Taiwan"},{"name":"School of Medicine, Tzu Chi University, Hualien 970374, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keng-Chang","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Orthopedics, Dalin Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Chiayi 622401, Taiwan"},{"name":"Endoscopic and Minimally Invasive Spine Center, Dalin Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Chiayi 622401, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chih-Wen","family":"Lin","sequence":"additional","affiliation":[{"name":"School of Medicine, Tzu Chi University, Hualien 970374, Taiwan"},{"name":"Department of Medical Imaging, Dalin Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Chiayi 622401, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chun-Hsi","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Orthopedics, Dalin Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Chiayi 622401, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuh-Feng","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Nuclear Medicine, Taipei Veterans General Hospital, Taipei 112201, Taiwan"},{"name":"Department of Biomedical Imaging and Radiological Sciences, National Yang Ming Chiao Tung University, Taipei 112304, Taiwan"},{"name":"Department of Medical Imaging and Radiological Technology, Yuanpei University of Medical Technology, Hsinchu 300102, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,5,26]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Nischal, N., Iyengar, K.P., Herlekar, D., and Botchu, R. (2023). Imaging of Cartilage and Chondral Defects: An Overview. Life, 13.","DOI":"10.3390\/life13020363"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"1478","DOI":"10.1148\/rg.2018180044","article-title":"Osteochondral Lesions of the Knee: Differentiating the Most Common Entities at MRI","volume":"38","author":"Gorbachova","year":"2018","journal-title":"Radiographics"},{"key":"ref_3","unstructured":"Nochehdehi, A.R., Nemavhola, F., Thomas, S., and Maria, H.J. (2024). Radiographic techniques for imaging knee joint. Cartilage Tissue and Knee Joint Biomechanics, Academic Press."},{"key":"ref_4","doi-asserted-by":"crossref","unstructured":"Jarecki, J., Wa\u015bko, M.K., Widuchowski, W., Tomczyk-Warunek, A., W\u00f3jciak, M., Sowa, I., and Blicharski, T. (2023). Knee Cartilage Lesion Management-Current Trends in Clinical Practice. J. Clin. Med., 12.","DOI":"10.3390\/jcm12206434"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1177\/03635465980260012901","article-title":"The prognostic value of quantitative bone scan in knee osteochondritis dissecans","volume":"26","author":"Paletta","year":"1998","journal-title":"Am. J. Sports Med."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1177\/1947603518786557","article-title":"Osteochondritis Dissecans of the Knee: Etiology and Pathogenetic Mechanisms. A Systematic Review","volume":"11","author":"Andriolo","year":"2020","journal-title":"Cartilage"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1177\/036354658301100509","article-title":"99m-Technetium phosphate compound joint scintigraphy in the management of juvenile osteochondritis dissecans of the femoral condyles","volume":"11","author":"Cahill","year":"1983","journal-title":"Am. J. Sports Med."},{"key":"ref_8","first-page":"1055","article-title":"SPECT\/CT bone scan fusion imaging in osteochondral lesions of the talus","volume":"50","author":"Zeng","year":"2009","journal-title":"J. Nucl. Med."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1177\/1947603517715736","article-title":"Osteochondritis Dissecans: Etiology, Pathology, and Imaging with a Special Focus on the Knee Joint","volume":"9","author":"Bruns","year":"2018","journal-title":"Cartilage"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1097\/00003086-198207000-00010","article-title":"Arthroscopic treatment of osteochondritis dissecans","volume":"167","author":"Guhl","year":"1982","journal-title":"Clin. Orthop. Relat. Res."}],"container-title":["Diagnostics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2075-4418\/16\/11\/1630\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T04:16:39Z","timestamp":1780460199000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2075-4418\/16\/11\/1630"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,26]]},"references-count":10,"journal-issue":{"issue":"11","published-online":{"date-parts":[[2026,6]]}},"alternative-id":["diagnostics16111630"],"URL":"https:\/\/doi.org\/10.3390\/diagnostics16111630","relation":{},"ISSN":["2075-4418"],"issn-type":[{"value":"2075-4418","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5,26]]}}}