{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T11:05:24Z","timestamp":1784027124829,"version":"3.55.0"},"reference-count":26,"publisher":"MDPI AG","issue":"14","license":[{"start":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T00:00:00Z","timestamp":1783987200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostics"],"abstract":"<jats:p>Background\/Objectives: Our aim is to describe the clinical, imaging, and histopathological features of odontogenic keratocyst in a Mexican cohort. Methods: This is a retrospective, descriptive, and cross-sectional study. Clinical records and histopathology reports (2015\u20132025) from multiple laboratories were reviewed. Slides stained with hematoxylin and eosin were evaluated by pathologists using standardized criteria. Descriptive statistics were performed. Results: A total of 106 cases were included. Ages ranged from 10 to 86 years (mean 33.4 \u00b1 17.7). There was a predominance of males (61\/106; 57.5%). The most frequent location was the posterior mandible (49\/106; 46.2%), followed by anterior mandible (30\/106; 28.3%), posterior maxilla (19\/106; 17.9%), and anterior maxilla (8\/106; 7.5%). Most cases were asymptomatic (73\/106; 68.9%). Association with an impacted tooth was documented in 37\/106 (34.9%) and root resorption in 26\/106 (24.5%). Satellite epithelial islands were observed in 8\/106 (7.5%), satellite cysts in 17\/106 (16.0%), and both findings in 4\/106 (3.8%). Chronic inflammation was present in 62\/106 (58.5%). Conclusions: In this Mexican series, odontogenic keratocyst predominated in males and, in the posterior mandible, was frequently asymptomatic, and showed satellite foci and chronic inflammation in a relevant proportion, reinforcing the need for clinical-imaging and histopathological correlation, as well as follow-up.<\/jats:p>","DOI":"10.3390\/diagnostics16142194","type":"journal-article","created":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T10:12:53Z","timestamp":1784023973000},"page":"2194","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Clinicopathological Characteristics of Odontogenic Keratocysts in the Mexican Population"],"prefix":"10.3390","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-4451-3006","authenticated-orcid":false,"given":"Karla J.","family":"Rios-Orta","sequence":"first","affiliation":[{"name":"School of Dentistry, Autonomous University of the State of Mexico, Toluca de Lerdo 50130, State of Mexico, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brenda J.","family":"Valdez-Vargas","sequence":"additional","affiliation":[{"name":"Orocentro Oral Medicine and Pathology Clinic, School of Dentistry, Autonomous University of the State of Mexico, Toluca de Lerdo 50130, State of Mexico, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8628-1680","authenticated-orcid":false,"given":"Paola L.","family":"Acevedo-Quezada","sequence":"additional","affiliation":[{"name":"School of Dentistry, Autonomous University of Baja California, Mexicali 21040, Baja California, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6714-7790","authenticated-orcid":false,"given":"Edith","family":"Lara-Carrillo","sequence":"additional","affiliation":[{"name":"Orocentro Oral Medicine and Pathology Clinic, School of Dentistry, Autonomous University of the State of Mexico, Toluca de Lerdo 50130, State of Mexico, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Evelyn V.","family":"Flores-Solano","sequence":"additional","affiliation":[{"name":"Orocentro Oral Medicine and Pathology Clinic, School of Dentistry, Autonomous University of the State of Mexico, Toluca de Lerdo 50130, State of Mexico, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3635-4850","authenticated-orcid":false,"given":"Norma G.","family":"Ib\u00e1\u00f1ez-Mancera","sequence":"additional","affiliation":[{"name":"Interdisciplinary Health Sciences Center (CICS), Santo Tom\u00e1s Unit (UST), Instituto Polit\u00e9cnico Nacional, Mexico City 11340, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-1784-0427","authenticated-orcid":false,"given":"Montserrat","family":"Escuadra-Landeros","sequence":"additional","affiliation":[{"name":"Division of Health Sciences, School of Dentistry, Universidad Intercontinental, Mexico City 14420, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonatan E.","family":"Flores-Riveroll","sequence":"additional","affiliation":[{"name":"School of Dentistry, National Autonomous University of Mexico, Mexico City 04510, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pen\u00e9lope I.","family":"Manzano-Galindo","sequence":"additional","affiliation":[{"name":"Puebla Maxillofacial Center, Puebla 72197, Puebla, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guillermo","family":"Molina-Vidal","sequence":"additional","affiliation":[{"name":"Puebla Maxillofacial Center, Puebla 72197, Puebla, Mexico"},{"name":"Cholula General Hospital, San Andr\u00e9s Cholula 72825, Puebla, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcos","family":"Hern\u00e1ndez-Nava","sequence":"additional","affiliation":[{"name":"Maxillofacial Surgery Service, \u201cLicenciado Adolfo L\u00f3pez Mateos\u201d Medical Center, Toluca de Lerdo 50226, Estado de M\u00e9xico, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 E.","family":"Gardu\u00f1o-Mej\u00eda","sequence":"additional","affiliation":[{"name":"Maxillofacial Surgery Service, \u201cLicenciado Adolfo L\u00f3pez Mateos\u201d Medical Center, Toluca de Lerdo 50226, Estado de M\u00e9xico, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0379-9626","authenticated-orcid":false,"given":"Saray","family":"Aranda-Romo","sequence":"additional","affiliation":[{"name":"School of Stomatology, Autonomous University of San Luis Potosi, San Luis Potosi 78290, S.L.P., Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francisco J.","family":"Tejeda-Nava","sequence":"additional","affiliation":[{"name":"School of Stomatology, Autonomous University of San Luis Potosi, San Luis Potosi 78290, S.L.P., Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana M.","family":"Santill\u00e1n-Reyes","sequence":"additional","affiliation":[{"name":"Orocentro Oral Medicine and Pathology Clinic, School of Dentistry, Autonomous University of the State of Mexico, Toluca de Lerdo 50130, State of Mexico, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sergio S.","family":"Utrera-L\u00f3pez","sequence":"additional","affiliation":[{"name":"Orocentro Oral Medicine and Pathology Clinic, School of Dentistry, Autonomous University of the State of Mexico, Toluca de Lerdo 50130, State of Mexico, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Norma Samanta","family":"Romero-Castro","sequence":"additional","affiliation":[{"name":"Academic Unit of Dentistry, Autonomous University of Guerrero, Acapulco 39070, Guerrero, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Salvador","family":"Reyes-Fern\u00e1ndez","sequence":"additional","affiliation":[{"name":"Academic Unit of Dentistry, Autonomous University of Guerrero, Acapulco 39070, Guerrero, Mexico"},{"name":"General Hospital of Acapulco, Guerrero State Health Secretariat, Acapulco 39901, Guerrero, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda F.","family":"Lara-Fonseca","sequence":"additional","affiliation":[{"name":"Pediatric Dentistry, School of Dentistry, Autonomous University of the State of Mexico, Toluca de Lerdo 50130, State of Mexico, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8796-7809","authenticated-orcid":false,"given":"Ulises","family":"Vel\u00e1zquez-Enriquez","sequence":"additional","affiliation":[{"name":"Orocentro Oral Medicine and Pathology Clinic, School of Dentistry, Autonomous University of the State of Mexico, Toluca de Lerdo 50130, State of Mexico, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6732-6388","authenticated-orcid":false,"given":"El\u00edas N.","family":"Salmer\u00f3n-Vald\u00e9s","sequence":"additional","affiliation":[{"name":"Orocentro Oral Medicine and Pathology Clinic, School of Dentistry, Autonomous University of the State of Mexico, Toluca de Lerdo 50130, State of Mexico, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rebeca S.","family":"Garc\u00eda-Toral","sequence":"additional","affiliation":[{"name":"Department of Health Sciences, Autonomous University of the State of Mexico, Toluca de Lerdo 50130, State of Mexico, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adri\u00e1n Juan","family":"Hern\u00e1ndez-Cruz","sequence":"additional","affiliation":[{"name":"La Perla General Hospital, Nezahualc\u00f3yotl 57820, State of Mexico, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adriana A.","family":"Morales-Valenzuela","sequence":"additional","affiliation":[{"name":"Orocentro Oral Medicine and Pathology Clinic, School of Dentistry, Autonomous University of the State of Mexico, Toluca de Lerdo 50130, State of Mexico, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oscar","family":"Ramos-Carrillo","sequence":"additional","affiliation":[{"name":"Oral Surgery and Comprehensive Diagnosis and Oral Patology, Private Practice, 307 Venustiano Carranza Nte., Col. Santa Teresita, Tepic 63020, Nayarit, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2376-915X","authenticated-orcid":false,"given":"F\u00e1tima","family":"Del Muro-Casas","sequence":"additional","affiliation":[{"name":"Academic Unit of Dentistry, Autonomous University of Zacatecas, Zacatecas 98160, Zacatecas, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0839-0771","authenticated-orcid":false,"given":"Victor H.","family":"Toral-Rizo","sequence":"additional","affiliation":[{"name":"Orocentro Oral Medicine and Pathology Clinic, School of Dentistry, Autonomous University of the State of Mexico, Toluca de Lerdo 50130, State of Mexico, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4457-704X","authenticated-orcid":false,"given":"Rogelio","family":"Gonzalez-Gonzalez","sequence":"additional","affiliation":[{"name":"Research Department, School of Dentistry, Ju\u00e1rez University of the State of Durango, Durango 34000, Durango, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,7,14]]},"reference":[{"key":"ref_1","first-page":"963","article-title":"Om keratocyster (kolesteatomer) i kaeberne","volume":"60","author":"Philipsen","year":"1956","journal-title":"Tandlaegebladet"},{"key":"ref_2","unstructured":"Barnes, L., Eveson, J.W., Reichart, P., and Sidransky, D. 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Assoc."}],"container-title":["Diagnostics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2075-4418\/16\/14\/2194\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T10:26:51Z","timestamp":1784024811000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2075-4418\/16\/14\/2194"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7,14]]},"references-count":26,"journal-issue":{"issue":"14","published-online":{"date-parts":[[2026,7]]}},"alternative-id":["diagnostics16142194"],"URL":"https:\/\/doi.org\/10.3390\/diagnostics16142194","relation":{},"ISSN":["2075-4418"],"issn-type":[{"value":"2075-4418","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7,14]]}}}