{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T03:03:03Z","timestamp":1784516583856,"version":"3.55.0"},"reference-count":49,"publisher":"MDPI AG","issue":"14","license":[{"start":{"date-parts":[[2026,7,18]],"date-time":"2026-07-18T00:00:00Z","timestamp":1784332800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostics"],"abstract":"<jats:p>Introduction: Angiosarcomas are rare malignant vascular tumors. Primary angiosarcoma of the ileum is extremely uncommon, with few cases reported in the literature. Case Report: We report the case of a 54-year-old woman who presented with abdominal pain and constipation. Endoscopic evaluation did not reveal a mass in the distal ileum; however, MRI identified a distal ileal stenosis, raising suspicion for Crohn\u2019s disease. Surgical resection was performed, and histopathological analysis confirmed the diagnosis of primary ileal angiosarcoma. Postoperative chemotherapy was attempted but not tolerated, and the patient subsequently developed suspected peritoneal progression approximately six months after surgery. Discussion: Due to its rarity and nonspecific symptoms, ileal angiosarcoma is often diagnosed late. Imaging may suggest a vascular tumor, but definitive diagnosis requires histopathological and immunohistochemical analysis. Prognosis is generally poor, with high metastatic potential. Conclusions: This case highlights the diagnostic challenges of ileal angiosarcoma, a very rare type of tumor of the small bowel.<\/jats:p>","DOI":"10.3390\/diagnostics16142245","type":"journal-article","created":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T02:32:08Z","timestamp":1784514728000},"page":"2245","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Stenosing Ileal Angiosarcoma Presenting as Subocclusive Syndrome: A Rare Case Report and Literature Review"],"prefix":"10.3390","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5087-9282","authenticated-orcid":false,"given":"Mircea Vasile","family":"Milaciu","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, 4th Medical Discipline, \u201dIuliu Ha\u021bieganu\u201d University of Medicine and Pharmacy, Republicii Street, No. 18, 400015 Cluj-Napoca, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-4090-0164","authenticated-orcid":false,"given":"Cezara Andreea","family":"Gerdanovics","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, 4th Medical Discipline, \u201dIuliu Ha\u021bieganu\u201d University of Medicine and Pharmacy, Republicii Street, No. 18, 400015 Cluj-Napoca, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4435-142X","authenticated-orcid":false,"given":"Olga Hilda","family":"Or\u0103\u0219an","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, 4th Medical Discipline, \u201dIuliu Ha\u021bieganu\u201d University of Medicine and Pharmacy, Republicii Street, No. 18, 400015 Cluj-Napoca, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3989-2291","authenticated-orcid":false,"given":"Angela","family":"Cozma","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, 4th Medical Discipline, \u201dIuliu Ha\u021bieganu\u201d University of Medicine and Pharmacy, Republicii Street, No. 18, 400015 Cluj-Napoca, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2756-5784","authenticated-orcid":false,"given":"Teodora Gabriela","family":"Alexescu","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, 4th Medical Discipline, \u201dIuliu Ha\u021bieganu\u201d University of Medicine and Pharmacy, Republicii Street, No. 18, 400015 Cluj-Napoca, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C\u0103lin Vasile","family":"Vlad","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, 4th Medical Discipline, \u201dIuliu Ha\u021bieganu\u201d University of Medicine and Pharmacy, Republicii Street, No. 18, 400015 Cluj-Napoca, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-1926-6456","authenticated-orcid":false,"given":"Anamaria Vl\u0103du\u021ba","family":"Tomoiag\u0103","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, 4th Medical Discipline, \u201dIuliu Ha\u021bieganu\u201d University of Medicine and Pharmacy, Republicii Street, No. 18, 400015 Cluj-Napoca, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vlad Alexandru","family":"Zolog","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, 4th Medical Discipline, \u201dIuliu Ha\u021bieganu\u201d University of Medicine and Pharmacy, Republicii Street, No. 18, 400015 Cluj-Napoca, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0007-8962","authenticated-orcid":false,"given":"Vlad Dumitru","family":"Brata","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Regional Institute of Gastroenterology and Hepatology \u201cProf. Dr. Octavian Fodor\u201d, 400394 Cluj-Napoca, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lorena","family":"Cium\u0103rnean","sequence":"additional","affiliation":[{"name":"2nd Department, Faculty of Nursing and Health Sciences, \u201dIuliu Ha\u021bieganu\u201d University of Medicine and Pharmacy, Republicii Street, No. 18, 400015 Cluj-Napoca, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicoleta Valentina","family":"Leach","sequence":"additional","affiliation":[{"name":"2nd Department, Faculty of Nursing and Health Sciences, \u201dIuliu Ha\u021bieganu\u201d University of Medicine and Pharmacy, Republicii Street, No. 18, 400015 Cluj-Napoca, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Flaviu","family":"Mure\u0219an","sequence":"additional","affiliation":[{"name":"4th Surgical Department, \u201cIuliu Ha\u021bieganu\u201d University of Medicine and Pharmacy, Republicii Street, No. 18, 400015 Cluj-Napoca, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Codru\u021ba Claudia","family":"Gherman Lencu","sequence":"additional","affiliation":[{"name":"Department 1, Fundamental Discipline, Endocrinology, \u201cIuliu Ha\u021bieganu\u201d University of Medicine and Pharmacy, Victor Babe\u0219 Street nr. 8, 400347 Cluj-Napoca, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adriana","family":"Zolog","sequence":"additional","affiliation":[{"name":"Clinical Hospital CF Cluj-Napoca, Republicii Street, No. 18, 400015 Cluj-Napoca, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anca","family":"Mihailov","sequence":"additional","affiliation":[{"name":"Clinical Hospital CF Cluj-Napoca, Republicii Street, No. 18, 400015 Cluj-Napoca, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8327-2444","authenticated-orcid":false,"given":"Mirela Georgiana","family":"Perne","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, 4th Medical Discipline, \u201dIuliu Ha\u021bieganu\u201d University of Medicine and Pharmacy, Republicii Street, No. 18, 400015 Cluj-Napoca, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,7,18]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1053\/j.sempedsurg.2014.07.001","article-title":"Other vascular tumors","volume":"23","author":"Adams","year":"2014","journal-title":"Semin. 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