{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T14:09:43Z","timestamp":1789999783445,"version":"4.0.1"},"reference-count":15,"publisher":"MDPI AG","issue":"18","license":[{"start":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T00:00:00Z","timestamp":1789689600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostics"],"abstract":"<jats:p>Background\/Objectives: To compare the visual outcomes between two extended depth-of-focus intraocular lenses (EDOF IOLs) in an Asian population. Methods: This retrospective single-center study included patients with senile cataract undergoing cataract surgery with implantation of either TECNIS PureSee or AcrySof IQ Vivity IOL. Visual and refractive outcomes such as visual acuity (VA), manifest refraction, and mean refractive spherical equivalent were compared up to post-operative month 6. Contrast sensitivity and defocus curves were evaluated monocularly, as well as binocularly if both eyes had the same IOL implanted. Results: Forty-nine eyes were evaluated\u201424 implanted with PureSee and 25 implanted with AcrySof IQ Vivity. The follow-up period was 6.4 \u00b1 1.1 months in the PureSee group and 6.4 \u00b1 1.0 months in the Vivity group (p = 1.0). There was no significant difference in postoperative visual outcomes at postoperative month 1 or 6. At post-operative month 6, unaided distance VA was 0.06 \u00b1 0.10 and 0.08 \u00b1 0.14 in the PureSee and Vivity groups, respectively (p = 0.519); unaided intermediate VA was 0.21 \u00b1 0.05 and 0.18 \u00b1 0.09, respectively (p = 0.192); and unaided near VA was 0.38 \u00b1 0.12 and 0.38 \u00b1 0.12, respectively (p = 0.842). Defocus and contrast sensitivity performance were broadly similar, except for Vivity\u2019s defocus being marginally better at 66 cm intermediate distance. At post-operative month 1, 69.2% of Vivity patients (n = 13) and 75.0% of PureSee patients (n = 4) denied haloes or glare. Conclusions: Both EDOF IOLs demonstrated comparable visual performances.<\/jats:p>","DOI":"10.3390\/diagnostics16183024","type":"journal-article","created":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T12:50:03Z","timestamp":1789995003000},"page":"3024","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Comparing Visual Outcomes Between Two Extended Depth-of-Focus Intraocular Lenses in an Asian Population"],"prefix":"10.3390","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5568-4188","authenticated-orcid":false,"given":"Jessica Q. H.","family":"Choo","sequence":"first","affiliation":[{"name":"Singapore National Eye Centre, 11 Third Hospital Ave, Singapore 168751, Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peng Y.","family":"Tan","sequence":"additional","affiliation":[{"name":"Singapore National Eye Centre, 11 Third Hospital Ave, Singapore 168751, Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Younian","family":"Yang","sequence":"additional","affiliation":[{"name":"Singapore National Eye Centre, 11 Third Hospital Ave, Singapore 168751, Singapore"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"conceptualization","vocabulary":"credit"},{"role":"methodology","vocabulary":"credit"},{"role":"data-curation","vocabulary":"credit"},{"role":"formal-analysis","vocabulary":"credit"},{"role":"writing-review-editing","vocabulary":"credit"}]},{"given":"Melissa H. Y.","family":"Wong","sequence":"additional","affiliation":[{"name":"Singapore National Eye Centre, 11 Third Hospital Ave, Singapore 168751, Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,9,18]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"e164","DOI":"10.1016\/j.ophtha.2020.09.026","article-title":"Multifocal and extended depth-of-focus intraocular lenses in 2020","volume":"128","author":"Rampat","year":"2021","journal-title":"Ophthalmology"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1097\/j.jcrs.0000000000000747","article-title":"Visual outcomes and safety of an extended depth-of-focus intraocular lens: Results of a pivotal clinical trial","volume":"48","author":"Chang","year":"2022","journal-title":"J. Cataract Refract. Surg."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"426","DOI":"10.3928\/1081597X-20200603-01","article-title":"European, multicenter, prospective, non-comparative clinical evaluation of an extended depth of focus intraocular lens","volume":"36","author":"Auffarth","year":"2020","journal-title":"J. Refract. Surg."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"4801","DOI":"10.2147\/OPTH.S344379","article-title":"Preliminary clinical outcomes of a new enhanced depth of focus intraocular lens","volume":"15","author":"Campos","year":"2021","journal-title":"Clin. Ophthalmol."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"12","DOI":"10.3928\/1081597X-20191114-01","article-title":"Visual performance of a small-aperture intraocular lens: First comparison of results after contralateral and bilateral implantation","volume":"36","author":"Ang","year":"2020","journal-title":"J. Refract. Surg."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"1297","DOI":"10.1097\/j.jcrs.0000000000000978","article-title":"Clinical outcomes in a U.S. registration study of a new EDOF intraocular lens with a nondiffractive design","volume":"48","author":"McCabe","year":"2022","journal-title":"J. Cataract Refract. Surg."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1038\/s41433-024-03041-0","article-title":"Optical and clinical simulated performance of a new refractive extended depth of focus intraocular lens","volume":"38","author":"Alarcon","year":"2024","journal-title":"Eye"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"2449","DOI":"10.2147\/OPTH.S400083","article-title":"The Novel Optical Design and Clinical Classification of a Wavefront-Shaping Presbyopia-Correcting Intraocular Lens","volume":"17","author":"Kohnen","year":"2023","journal-title":"Clin. Ophthalmol."},{"key":"ref_9","unstructured":"Schwiegerling, J., Gu, X., Hong, X., Lemp-Hull, J., and Merchea, M. (2026, September 15). Optical Principles of Extended Depth of Focus IOLs. Available online: https:\/\/us.alconscience.com\/sites\/g\/files\/rbvwei1736\/files\/pdf\/Optical-Principles-of-EDOF-US-CAT-2000006.pdf."},{"key":"ref_10","unstructured":"Hong, X., Choi, M.-T., Karakelle, M., Zhang, X., Simpson, M.J., Zhang, Y., and Novartis, A.G. (2016). Extended Depth of Focus (EDOF) Lens to Increase Pseudo-Accommodation by Utilizing Pupil Dynamics. (US RE45,969 E), United States Reissued Patent."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"5537","DOI":"10.1167\/iovs.10-5341","article-title":"The development of an instrument to measure quality of vision: The Quality of Vision (QoV) questionnaire","volume":"51","author":"McAlinden","year":"2010","journal-title":"Investig. Ophthalmol. Vis. 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Surg."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1097\/j.jcrs.0000000000000712","article-title":"Multicountry clinical outcomes of a new nondiffractive presbyopia-correcting IOL","volume":"48","author":"Bala","year":"2022","journal-title":"J. Cataract Refract. Surg."}],"container-title":["Diagnostics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2075-4418\/16\/18\/3024\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T13:19:08Z","timestamp":1789996748000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2075-4418\/16\/18\/3024"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,18]]},"references-count":15,"journal-issue":{"issue":"18","published-online":{"date-parts":[[2026,9]]}},"alternative-id":["diagnostics16183024"],"URL":"https:\/\/doi.org\/10.3390\/diagnostics16183024","relation":{},"ISSN":["2075-4418"],"issn-type":[{"value":"2075-4418","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,18]]}}}